Joseph W Rossano MD

Pediatric Cardiac Critical Care, Pediatric Heart Failure and Heart Transplantation

Chief, Division of Cardiology Co-Executive Director, the Cardiac Center Jennifer Terker Endowed Chair in Pediatric Cardiology Professor of Pediatrics at the Children’s Hospital of Philadelphia Perelman School of Medicine at the University of Pennsylvania

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3401 Civic Center Blvd# ChildrenPhiladelphia, PA 19104
Phone+1 215-590-4040
Fax+1 267-426-9800

Education & Training

Baylor College of MedicineFellowship, Pediatric Cardiology, 2004 - 2008
University of WashingtonResidency, Pediatrics, 2002 - 2004
University of WashingtonInternship, Pediatrics, 2001 - 2002
University of Arizona College of MedicineClass of 2001, MD

Certifications & Licensure

PA State Medical License 2011 - 2026
TX State Medical License 2007 - 2024
WA State Medical License 2001 - 2004
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Cardiology

Clinical Trials

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM Start of enrollment: 2014 Mar 01
Completed
Phase 2
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart Failure Start of enrollment: 2016 Nov 03
Completed
Phase 2, Phase 3
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score Start of enrollment: 2018 Jan 29
Active, not recruiting
Phase 3
Open-label Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With HF Start of enrollment: 2019 May 02
COMPLETED
PHASE3
COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C Start of enrollment: 2020 Nov 19
Completed
Intramyocardial Injection of Autologous UCB-MNC During Fontan Surgery for SRV Dependent CHD Start of enrollment: 2021 Jun 01
Active, not recruiting
Phase 1
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopa...
Luke Wooster, Matthew J O'Connor, Xuemei Zhang, Constantine D Mavroudis, Katsuhide Maeda
Circulation. 2025-03-25
Hardly a Windfall: Prescribing Practices in Pediatric Heart Failure Around Food and Drug Administration Approval.
Avital B Ludomirsky, Jonathan B Edelson, Kimberly Y Lin, Justin H Berger, Matthew J O'Connor
JACC. Advances. 2025-03-19
Low Penetrance Sarcomere Variants Contribute to Additive Risk in Hypertrophic Cardiomyopathy.
Joshua K Meisner, Aaron Renberg, Eric D Smith, Yao-Chang Tsan, Brynn Elder
Circulation. 2025-03-18

Journal Articles

Measuring Quality in Pediatric Heart Transplantation—an Important but Challenging Goal
Kimberly Y Lin, Joseph W Rossano, JAMA Network Open

Lectures

Panelist: What I Would do and Why (Panel Discussion #1)
2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019

Authored Content

Rivaroxaban Versus Acetylsalicylic Acid in Children After Fontan: The UNIVERSE Study Randomized Clinical TrialApril 2022
Something Old, Something NewFebruary 2022

Press Mentions

Lifetime Achievement and Presidential Citation Awardees: Making a Difference in CardiologyMarch 29th, 2025
More Than $1.1M Raised at the 2025 Philly Spin-In to Benefit Cardiac Center at Children’s Hospital of PhiladelphiaMarch 14th, 2025
Children's Hospital of Philadelphia Receives Multi-Million Dollar Gift from Topolewski Family to Advance Pediatric Heart Valve Research and Establish Endowed Chair in CardiologyMay 18th, 2023
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