JosephGerardGleesonMD

Director of Neuroscience Research at Rady Children’s Institute for Genomic Medicine and Rady Professor of Neuroscience at UC San Diego School of Medicine

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Office
8010 Frost St
Ste 510
San Diego, CA 92123
Phone+1 858-966-5819

Fax+1 858-309-6301

Education & Training

Boston Children’s Hospital/Beth Israel Deaconess Medical Center/Harvard Medical SchoolResidency, Child Neurology, 1993 - 1996
Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 1991 - 1993
University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 1991

Certifications & Licensure

CA State Medical License 1999 - 2025
NY State Medical License 2014 - 2016
American Board of Psychiatry and Neurology Neurology with Special Qualification in Child Neurology

Awards, Honors, & Recognition

Investigator Howard Hughes Medical Institute

Publications & Presentations

PubMed

A comparative view of human and mouse telencephalon inhibitory neuron development.
Changuk Chung, Joseph Girgiss, Joseph G Gleeson
Development. 2025-01-01
Lipidomic profiling of mouse brain and human neuron cultures reveals a role forin mTOR-dependent neuronal migration.
Isaac Tang, Ashna Nisal, Alex Reed, Timothy B Ware, Anide Johansen
Science Translational Medicine. 2025-01-01
Biallelic variants in GTF3C3 result in an autosomal recessive disorder with intellectual disability.
Lachlan De Hayr, Laura E R Blok, Kerith-Rae Dias, Jingyi Long, Anaïs Begemann
Genetics in Medicine. 2025-01-01

Journal Articles

Biallelic Loss of Human CTNNA2, Encoding αN-Catenin, Leads to ARP2/3 Complex Overactivity and Disordered Cortical Neuronal Migration
Joseph G Gleeson, Ian Miller, Bruce A Barshop, William B Dobyns, Murat Gunel, Nature
Defining the Phenotypic Spectrum of SLC6A1 Mutations
Lance H Rodan, Heather C Mefford, Lynne M Bird, Sara Chadwick Reichert, Mark Nespeca, Orrin Devinsky, Sarah Hopkins, Laura Pisani, John J Millichap, Joseph G Gleeson, Epilepsia

Press Mentions

Researchers Discover Cause of Childhood Epilepsy: The Tribune IndiaJanuary 14th, 2023
Researchers Find Cause of Epilepsy in ChildrenJanuary 13th, 2023
Where Neurons Begin in the Brain Isn’t Necessarily Where They EndApril 22nd, 2022
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Grant Support

University Of California, SAN Diego Neuroscience Microscopy Imaging CoreNational Institute Of Neurological Disorders And Stroke2008–2012
Project 1National Institute Of Neurological Disorders And Stroke2008–2012
Project 3. Genetic Models Of Human Structural Brain Defects In ZebrafishEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Project 2. Mouse Models Of Human Structural Brain Disorders: Forward And ReversEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Project 1. Genetic Dissection Of Human Structural Brain Disorders From Inbred POEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Developmental Mechanisms Of Human Structural Brain DefectsEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Core C. Bioinformatics Genomics CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Core B. Highl-Throughput Sequencing Genomics CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Core A. Administrative CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Jouberin And Nephrocystin In Joubert SyndromeNational Institute Of Neurological Disorders And Stroke2007–2011
Molecular Characterization Of Joubert SyndromeNational Institute Of Neurological Disorders And Stroke2004–2011
Doublecortin In Neuronal MigrationNational Institute Of Neurological Disorders And Stroke2002–2011
Super-Resolution Imaging At The UCSD Microscopy CoreNational Center For Research Resources2010
Jouberin And Nephrocystin In Joubert SyndromeNational Center For Research Resources2008–2009
Doublecortin In Neuronal MigrationNational Center For Research Resources2008–2009
Role Of The Doublecortin/Spinophilin Interaction In Neurite OutgrowthNational Center For Research Resources2008
Patient-Oriented Research In Recessive Pediatric Brain DiseasesNational Institute Of Neurological Disorders And Stroke2007–2008
Spinophilin And Microtubule Bundling At The Axonal "Wrist"National Center For Research Resources2007
U Of Calif, SAN Diego Neuroscience Microscopy ImagingNational Institute Of Neurological Disorders And Stroke2003–2007
Volumetric Analysis Of Mice With MicrocephalyNational Center For Research Resources2004–2006
Molecular Mechanisms Of Neuronal MigrationNational Institute Of Neurological Disorders And Stroke2002–2006
UCSD Neuroscience Microscopy Imaging CoreNational Institute Of Neurological Disorders And Stroke2005
Advances In Midbrain/Hindbrain MalformationsNational Institute Of Neurological Disorders And Stroke2005