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Office
200 W Arbor Dr
San Diego, CA 92103Phone+1 858-822-6197
Summary
- I am a board certified otolaryngologist at UC San Diego Health. I am a a clinically active head and neck surgeon and currently direct a laboratory focused on the molecular biologic basis of head and neck cancer.
My interests include minimally invasive treatment of tumors of the oral cavity, larynx, pharynx, thyroid, and neck, with an interest in tumors of the skull base, salivary glands, and premalignant conditions of the upper aerodigestive tract. I also have an deep interest in HPV-related cancers of the throat, as well as premalignant conditions of the upper aerodigestive tract.
Education & Training
- Johns Hopkins Carey Business SchoolNon-degree, Business of Medicine, 2012 - 2013
- Johns Hopkins UniversityResidency, Otolaryngology - Head and Neck Surgery, 1994 - 1999
- Johns Hopkins University School of MedicineInternship, Transitional Year, 1993 - 1994
- Harvard Medical SchoolClass of 1993
- Amherst CollegeB.A., Chemistry, 1985
Certifications & Licensure
- CA State Medical License 2015 - 2027
- MD State Medical License 1995 - 2016
- NY State Medical License 1999 - 2001
- American Board of Otolaryngology - Head and Neck Surgery Otolaryngology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification eClinicalWorks EHR, eClinicalWorks LLC, 2012-2013
- Top Doctor Castle Connolly, 2012
- America's Top Doctors for Cancer Castle Connolly, 2011
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Clinical Trials
- Cetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract Start of enrollment: 2007 May 01
Publications & Presentations
PubMed
- Clinicopathologic Features of Oral Verrucous Carcinoma: A Systematic Review and Meta-Analysis.Steven Duncan, Andrey Finegersh, Ryan K Orosco, Nathaniel Wu, Kevin T Brumund
The Annals of Otology, Rhinology, and Laryngology. 2024-11-11 - Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability.Malay K Sannigrahi, Lovely Raghav, Dominick J Rich, Travis P Schrank, Joseph A Califano
Biorxiv. 2024-11-04 - Inhibition of novel human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer.Takuya Nakagawa, Jens Luebeck, Kaiyuan Zhu, Joshua T Lange, Roman Sasik
Research Square. 2024-09-05
Journal Articles
- Integrated Time Course Omics Analysis Distinguishes Immediate Therapeutic Response from Acquired ResistanceJoseph A Califano, Christine H Chung, BioMed Central
- The Epidermal Growth Factor Receptor Axis: Support for a New Target for Oral PremalignancyRosin MP, Califano JA, Cancer Prev Res, 6/22/2010
- Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivoZhao Y, Hao Y, Ji H, Fang Y, Guo Y, Sha W, Zhou Y, Pang X, Southerland WM, Califano JA, Gu X, Cancer Prev Res, 6/1/2010
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Books/Book Chapters
Lectures
- "Integrating high throughput analysis to define treatment strategies for HNSCC"New York, NY - 7/29/2014
- "A transcription factor signature of HNSCC implicates STAT and NFKB activation in HPV negative tumors."New York, NY - 7/29/2014
- Moderator, "Thyroid-Neck II"New York, NY - 7/27/2014
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Press Mentions
- Higher Cancer Risk with Heavy Cannabis Use – US StudyAugust 21st, 2024
- Daily Marijuana Use Linked to Increased Risk of Deadly Head and Neck Cancers, Study FindsAugust 10th, 2024
- Heavy Cannabis Use Tied to Increased Head and Neck Cancer RiskAugust 8th, 2024
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Grant Support
- A NOVEL POINT OF CARE TEST FOR ORAL AND OROPHARYNGEAL CANCER RISKNIH2017–2021
- OPTIMIZING AN ASSAY FOR HIGH RISK HPV DNA IN BODY FLUIDSNCI2017–2019
- Integrative Pathway Analysis Of Epigenomic/Transcriptional Alteration In HnsccNational Institute Of Dental &Craniofacial Research2010
- Validation Of Epigenetic Biomarkers Of Head And Neck Cancer Progression--OldNational Institute Of Dental &Craniofacial Research2009–2010
- Tadalafil Induced Modulation Of Immune Response In HnsccNational Cancer Institute2009–2010
- Integrative Pathway Analysis Of Eqigenomic/Transcriptional Alteration In HnsccNational Institute Of Dental &Craniofacial Research2009
- Cetuximab For Treatment Of High-Risk Pre-Malignant Upper Aerodigestive LesionsNational Cancer Institute2008–2009
- Hu/Jhu Head And Neck Cancer Translational Research And *National Cancer Institute2005–2008
- Molecular Anatomy Of Mitochondria In HnscNational Institute Of Dental &Craniofacial Research2004–2006
Professional Memberships
- Fellow
External Links
- Johns Hopkins Physicianshttp://www.hopkinsmedicine.org/joseph-califano
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