JoseCastillo-MancillaMD

Infectious Disease • Aurora, CO

HIV/AIDS Medicine

Associate Professor, Medicine, University of Colorado School of Medicine

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Office
12605 E 16th Ave
Aurora, CO 80045
Phone+1 720-848-0000

Education & Training

Cleveland Clinic FoundationFellowship, Infectious Disease, 2003 - 2005
Mount Sinai Medical Center of FloridaResidency, Internal Medicine, 2000 - 2003
Universidad La Salle School of MedicineClass of 1999

Certifications & Licensure

CO State Medical License 2008 - 2025
NM State Medical License 2005 - 2010
OH State Medical License 2003 - 2005
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Quantifying Drug Adherence and Drug Exposure to Antiretroviral Therapy Start of enrollment: 2013 Dec 01
Completed
Pre-Exposure Prophylaxis (PrEP) Adherence Monitoring Using Dried Blood Spots Start of enrollment: 2014 Apr 01
Completed
Phase 1, Phase 2
Impact of ART Adherence on HIV Persistence and Inflammation Start of enrollment: 2016 Jan 01
Completed
The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE Start of enrollment: 2019 Mar 28
Recruiting
Phase 3
Quantification of Tenofovir Alafenamide Adherence (QUANTI-TAF) Start of enrollment: 2019 Nov 21
Active, not recruiting
Adherence and Clinical Correlates in Persons With HIV on TAF Start of enrollment: 2022 Apr 25
Recruiting
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

9 citations
Pharmacokinetics of tenofovir monoester and association with intracellular tenofovir diphosphate following single-dose tenofovir disoproxil fumarate.
Kristina M Brooks, Mustafa E Ibrahim, Jose R Castillo-Mancilla, Samantha MaWhinney, Keisha Alexander
The Journal of Antimicrobial Chemotherapy. 2019-08-01
181 citations
Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots following Directly Observed Therapy.
Peter L. Anderson, Albert Y. Liu, Jose R Castillo-Mancilla, Edward M. Gardner, Sharon M Seifert
Antimicrobial Agents and Chemotherapy. 2017-12-21
102 citations
Application of an intracellular assay for determination of tenofovir-diphosphate and emtricitabine-triphosphate from erythrocytes using dried blood spots.
Jia-Hua Zheng, Caitlin Rower, Kevin McAllister, Jose R Castillo-Mancilla, Brandon Klein
Journal of Pharmaceutical and Biomedical Analysis. 2016-04-15

Press Mentions

Trial to Evaluate Long-Acting Injectables for People Struggling to Adhere to Daily Oral ARTMay 27th, 2019
Clinical Trial at CU Anschutz Will Test Injectable vs. Oral Medications to Treat HIVMay 9th, 2019
Emtricitabine in Dried Blood Spots Predicts HIV Viral SuppressionFebruary 13th, 2019
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Committees

Chair, ACTG-Underrepresented Populations Committee 2016 - Present

Professional Memberships

Infectious Disease Society of America - IDSA
Member

Other Languages

Spanish

External Links

Research Interestshttp://www.ucdenver.edu/academics/colleges/medicalschool/departments/medicine/InfectiousDiseases/Pages/Jose-Castillo-Mancilla-Research.aspx