Jonathan Sylvan Williams MD MMSc
Adrenal Disease, Diabetes, Obesity
Associate Professor of Medicine, Harvard Medical School
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221 Longwood Ave# BrighamBoston, MA 02115
Phone+1 617-732-5661
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Education & Training
Harvard Medical SchoolMMSc, ., ., 2002 - 2004
Mass General Brigham/Brigham and Women's HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2001 - 2004- Mass General Brigham/Brigham and Women's HospitalResidency, Internal Medicine, 1998 - 2001
Drexel University College of MedicineClass of 1998
Brigham Young UniversityBS, Microbiology, 1986 - 1992
Certifications & Licensure
FL State Medical License 2011 - 2025
MA State Medical License 2000 - 2025
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Early Career Mentoring Award Brigham and Women's Hospital, 2012
- Member Alpha Omega Alpha, 1996
Clinical Trials
- Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity Start of enrollment: 2010 Feb 01
- Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance Start of enrollment: 2010 Jun 01
- Caveolin-1 and Vascular Dysfunction Start of enrollment: 2010 Oct 01
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Publications & Presentations
PubMed
- Salt Sensitivity of Blood Pressure in Black Individuals with Striatin and Lysine Specific Demethylase-1 Risk Alleles.Andrea V Haas, Rayan Uddin, Huiling Ngu, Lindsey Porter, Mahyar Heydarpour
The Journal of Clinical Endocrinology and Metabolism. 2025-02-27 - Increased Salt Sensitive Blood Pressure in Women Versus men: Is Relative Hyperaldosteronism the Mechanism?Ezgi Caliskan Guzelce, Kelly Yin Han Wong, Mahyar Heydarpour, Luminita H Pojoga, Jose Romero
The Journal of Clinical Endocrinology and Metabolism. 2024-12-19 - Mineralocorticoid Receptor and Aldosterone: Interaction Between NR3C2 Genetic Variants, Sex, and Age in a Mixed Cohort.Mahyar Heydarpour, Wasita W Parksook, Luminita H Pojoga, Gordon H Williams, Jonathan S Williams
The Journal of Clinical Endocrinology and Metabolism. 2024-12-18
Grant Support
- Dietary BiomarkersNational Institutes of Health/Food and Drug Administration2022–2026
- Striatin and HypertensionNIH/NHLBI2019–2023
- Harvard CTSANIH2018–2023
- GNAI and Salt-sensitivityNIH/NHLBI2018–2022
- Effect of Statin Use on Aldosterone Secretion (R01)NIH/NHLBI2017–2021
- LSD1 and salt-sensitivity in human hypertensionNIH/NHLBI2016–2021
- Metabolic effects of sleep and circadian disruptionNIH/NIA2013–2019
- Striatin and aldosteroneNIH/NHLBI2013–2017
- Investigator Initiated Research ProgramNovartis Research Institute2010–2012
- K23National Heart Lung and Blood Institute2007–2012
Committees
- Chair, Mass General Brigham, IRB 2022 - Present
- Lead Medical Research Officer, Brigham and Women's Hospital 2020 - Present
- Board of Directors, Association for Patient-Oriented Research
- Associate Editor, Metabolism: Clinical and Experimental
Other Languages
- Spanish
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