JonathanSylvanWilliamsMDMMSc

Endocrinology • Boston, MA

Adrenal Disease, Diabetes, Obesity

Associate Professor of Medicine, Harvard Medical School

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Office
221 Longwood Ave
# Brigham
Boston, MA 02115
Phone+1 617-732-5661

Education & Training

Harvard Medical SchoolMMSc, ., ., 2002 - 2004
Brigham and Women's HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2001 - 2004
Brigham and Women's HospitalResidency, Internal Medicine, 1998 - 2001
Drexel University College of MedicineClass of 1998

Certifications & Licensure

MA State Medical License 2000 - 2025
FL State Medical License 2011 - 2022
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

Early Career Mentoring Award Brigham and Women's Hospital, 2012
Member Alpha Omega Alpha, 1996

Clinical Trials

Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity Start of enrollment: 2010 Feb 01
Completed
Not Applicable
Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance Start of enrollment: 2010 Jun 01
Terminated
Not Applicable
Caveolin-1 and Vascular Dysfunction Start of enrollment: 2010 Oct 01
Active, not recruiting
Phase 1
Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism Start of enrollment: 2014 Mar 31
Completed
Not Applicable
The Role of Minerelocorticoid Receptor on Modulating Aldosterone Production Start of enrollment: 2016 Jan 01
Completed
Phase 1
Effect of Statin Use on Aldosterone Secretion Start of enrollment: 2016 Apr 01
Completed
Phase 1
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans Start of enrollment: 2017 Jan 02
Active, not recruiting
Not Applicable
MR Antagonist and STRIATIN Start of enrollment: 2019 Jan 15
Completed
Phase 4
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Publications & Presentations

PubMed

67 citations
The Independent Association Between 25‐Hydroxyvitamin D and Adiponectin and Its Relation With BMI in Two Large Cohorts: The NHS and the HPFS
Anand Vaidya, Jonathan S. Williams, John P. Forman
Obesity. 2012-01-01
145 citations
Clinical risk factors for the development of hypertension in patients treated with inhibitors of the VEGF signaling pathway.
Ole-Petter R. Hamnvik, Toni K. Choueiri, Alexander Turchin, Rana R. McKay, Lipika Goyal
Cancer. 2015-01-15
42 citations
THE FOK1 VITAMIN D RECEPTOR GENE POLYMORPHISM IS ASSOCIATED WITH PLASMA RENIN ACTIVITY IN CAUCASIANS
Anand Vaidya, Bei Sun, John P. Forman, Paul N. Hopkins, Nancy J. Brown
Clinical Endocrinology. 2011-06-01

Grant Support

Dietary BiomarkersNational Institutes of Health/Food and Drug Administration2022–2026
Striatin and HypertensionNIH/NHLBI2019–2023
Harvard CTSANIH2018–2023
GNAI and Salt-sensitivityNIH/NHLBI2018–2022
Effect of Statin Use on Aldosterone Secretion (R01)NIH/NHLBI2017–2021
LSD1 and salt-sensitivity in human hypertensionNIH/NHLBI2016–2021
Metabolic effects of sleep and circadian disruptionNIH/NIA2013–2019
Striatin and aldosteroneNIH/NHLBI2013–2017
Investigator Initiated Research ProgramNovartis Research Institute2010–2012
K23National Heart Lung and Blood Institute2007–2012

Committees

Chair, Mass General Brigham, IRB 2022 - Present
Lead Medical Research Officer, Brigham and Women's Hospital 2020 - Present
Board of Directors, Association for Patient-Oriented Research
Associate Editor, Metabolism: Clinical and Experimental

Other Languages

Spanish