Jonathan Paul Piccini Sr. MD
Cardiac Electrophysiology
Professor of Medicine, Director of Cardiac Electrophysiology; Duke Heart Center & Duke Clinical Research Institute, Duke University
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40 Duke Medicine CirDurham, NC 27710
Phone+1 919-684-8111
Fax+1 919-668-7057
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Summary
- Jonathan P. Piccini, MD, MHS, FACC, FAHA, FHRS is a clinical cardiac electrophysiologist and Professor of Medicine and Population Health at Duke University and the Duke Clinical Research Institute. He is the Director of the Cardiac Electrophysiology section at the Duke Heart Center. His focus is on the care of patients with atrial fibrillation and complex arrhythmias, with particular emphasis on catheter ablation, pacing, and lead extraction. His research interests include the development and evaluation of innovative cardiovascular interventions for the treatment of heart rhythm disorders. He serves on the Board of Trustees of the Heart Rhythm Society, is an Associate Editor at JACC: Clinical Electrophysiology, and is an elected member of the American Society for Clinical Investigation. Dr. Piccini has more than 600 publications in the field of heart rhythm medicine.
Education & Training
Duke University HospitalFellowship, Clinical Cardiac Electrophysiology, 2009 - 2011- Duke University HospitalFellowship, Cardiovascular Disease, 2005 - 2009
Johns Hopkins UniversityResidency, Internal Medicine, 2002 - 2005
Northwestern University The Feinberg School of MedicineClass of 2002
Certifications & Licensure
NC State Medical License 2005 - 2025
American Board of Internal Medicine Cardiovascular Disease- American Board of Internal Medicine Clinical Cardiac Electrophysiology
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
- Fellow (FACC) American College of Cardiology
Clinical Trials
- Risk of Life-threatening Heart Rhythm Disturbances in Siblings Start of enrollment: 2007 Jul 01
- Ranolazine Implantable Cardioverter-Defibrillator Trial Start of enrollment: 2011 Sep 01
- Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure Start of enrollment: 2014 Apr 01
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Publications & Presentations
PubMed
- TAILORing AI-guided treatment for atrial fibrillation.Zak Loring, Jonathan P Piccini
Nature Medicine. 2025-04-02 - Factor XI inhibitors for the prevention and treatment of venous and arterial thromboembolism.Davide Capodanno, John H Alexander, M Cecilia Bahit, John W Eikelboom, C Michael Gibson
Nature Reviews. Cardiology. 2025-03-31 - Asundexian or Apixaban in Patients With Atrial Fibrillation According to Prior Oral Anticoagulant Use: A Subgroup Analysis of the OCEANIC-AF Randomized Clinical Trial.John H Alexander, Elizabeth J Lydon, Jonathan P Piccini, Thomas Viethen, Jonas Oldgren
JAMA Cardiology. 2025-03-26
Journal Articles
- Focus on Transcatheter Aortic Valve Replacement Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic...Jonathan P Piccini, Vinod H Thourani, Samir Kapadia, David Cohen, Eric Peterson, Matthew W Sherwood, Ajay Kirtane, Sreekanth Vemulapalli, Amit N Vora, Bhaskar Bhardwaj, ScienceDirect
- Mineralocorticoid Receptor Antagonism for the Treatment of AF and HFpEFJonathan P Piccini, Adam D DeVore, ScienceDirect
- Incremental Prognostic Value of Renal Function for Stroke Prediction in Atrial Fibrillation☆Gregg C Fonarow, Kenneth W Mahaffey, Sean D Pokorney, Eric D Peterson, Jonathan P Piccini, International Journal of Cardiology
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Press Mentions
Lessons from Medtronic’s Define AFib Study of Implantable Cardiac MonitorsMarch 25th, 2025- NOW PUBLISHED: Compared with PV Isolation Alone, AI-Guided Ablation Lowers AF at 12 MonthsFebruary 18th, 2025
- Study Shows Medtronic ICM Accurately Predicts Risk Thresholds for AFib Patients Using AIJanuary 29th, 2025
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Grant Support
- Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)DUKE UNIVERSITY2021–2026
Professional Memberships
- Member
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