Jon Edgar Grant MD

Psychiatry•Chicago, IL

Professor, Psychiatry, University of Minnesota Medical School

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5841 S Maryland AveChicago, IL 60637
Phone+1 888-824-0200
Fax+1 773-834-6761

Education & Training

University of MinnesotaResidency, Psychiatry, 1999 - 2003
The Warren Alpert Medical School of Brown UniversityClass of 1999

Certifications & Licensure

IL State Medical License 2012 - 2026
MN State Medical License 2001 - 2026
RI State Medical License 2003 - 2020
American Board of Psychiatry and Neurology Psychiatry

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2014
Chicago Magazine: Top Doctors Castle Connolly, 2014

Clinical Trials

An Open-Label Study Of Lamictal In Neurotic Excoriation Start of enrollment: 2006 Jan 01
Completed
Phase 2
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling Start of enrollment: 2006 Jan 01
Completed
Phase 1
Double-Blind Naltrexone in Kleptomania Start of enrollment: 2006 May 01
Completed
Phase 2
Cognitive Behavioral Therapy for Pathological Gambling Start of enrollment: 2006 Jun 01
Completed
Phase 2
N-Acetyl Cysteine in Trichotillomania Start of enrollment: 2006 Jul 01
Completed
Phase 2
Naltrexone in the Treatment of Pyromania Start of enrollment: 2007 Jun 01
Withdrawn
Phase 2
Memantine Treatment Study of Pathological Gambling Start of enrollment: 2007 Dec 01
Completed
Phase 2
Effectiveness of Deep Brain Stimulation for Treating People With Treatment Resistant Obsessive-Compulsive Disorder
ACTIVE_NOT_RECRUITING
PHASE4
Naltrexone in the Treatment of Trichotillomania Start of enrollment: 2008 Aug 01
Completed
Phase 2
Memantine Treatment of Compulsive Buying Start of enrollment: 2008 Dec 01
Completed
Phase 2
Memantine in the Treatment of Kleptomania Start of enrollment: 2009 Mar 01
Completed
Phase 2
Tolcapone Treatment of Pathological Gambling Start of enrollment: 2009 Jun 01
Completed
Phase 2
N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers Start of enrollment: 2009 Sep 01
Completed
Phase 2
N-Acetyl Cysteine in Pathologic Skin Picking Start of enrollment: 2012 Sep 01
Completed
Phase 2
Marinol in Trichotillomania or Obsessive Compulsive Disorder Start of enrollment: 2010 Apr 01
Completed
Phase 2
Clinical Study to Determine if Ecopipam Can Reduce Urges to Gamble Start of enrollment: 2010 Oct 01
Completed
Phase 2
Efficacy and Safety Study of Low-Dose Ondansetron For Adjunctive Therapy In Adult Patients With Obsessive-Compulsive Disorder Start of enrollment: 2011 Jan 01
Terminated
Phase 2
Susceptibility to Pathological Gambling
COMPLETED
NA
Double-Blind Treatment of Major Depressive Disorder With Vilazodone Start of enrollment: 2013 May 01
Completed
Phase 2
Inositol in Trichotillomania Start of enrollment: 2013 May 01
Completed
Phase 2
Milk Thistle in Trichotillomania in Children and Adults Start of enrollment: 2015 Mar 01
Completed
Phase 2
Milk Thistle in Body Dysmorphic Disorder Start of enrollment: 2016 Oct 01
Withdrawn
Phase 2
Tolcapone in Obsessive Compulsive Disorder Start of enrollment: 2018 Mar 20
Completed
Phase 2, Phase 3
Brexpiprazole in Borderline Personality Disorder Start of enrollment: 2018 Nov 26
Completed
Phase 2
Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors Start of enrollment: 2018 Oct 01
Completed
Phase 2, Phase 3
Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension Start of enrollment: 2019 Oct 04
Completed
Phase 2
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Publications & Presentations

PubMed

Comparing efficacy of serotonergic, opioidergic, and glutamatergic drugs in gambling disorder: A pooled analysis of response trajectories versus placebo.
Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Carmine Gelormini, Roberto Guidotti
Journal of Psychiatric Research. 2025-03-29
Transdiagnostic Compulsivity Traits in Problematic Use of the Internet Among UK Residents: Cross-Sectional Network Analysis Study.
Chang Liu, Samuel Chamberlain, Konstantinos Ioannidis, Jeggan Tiego, Jon Grant
Journal of Medical Internet Research. 2025-03-26
3 citations
Pharmacological management of gambling disorder: A systematic review and network meta-analysis.
Konstantinos Ioannidis, Cinzia Del Giovane, Charidimos Tzagarakis, Jeremy E Solly, Samuel J Westwood
Comprehensive Psychiatry. 2025-02-01

Journal Articles

The British Journal of Psychiatry
Jon Grant, MD, Cambridge Journals
The British Journal of Psychiatry
Jon Grant, MD, Cambridge Journals
The British Journal of Psychiatry
Jon Grant, MD, Cambridge Journals
The British Journal of Psychiatry
Jon Grant, MD, Cambridge Journals
The British Journal of Psychiatry
Jon Grant, MD, Cambridge Journals
Body-Focused Repetitive Behaviors and the Dermatology Patient
Jon Grant, MD, ScienceDirect
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Lectures

The British Journal of Psychiatry
161st Annual Meeting, Washington, DC, USA

Authored Content

Salivary Sex Hormones in Adolescent Females with Trichotillomania☆May 2018
Salivary Sex Hormones in Adolescent Females with Trichotillomania☆May 2018
The British Journal of PsychiatryFebruary 2018
Major Depressive Disorder and Depressive Symptoms in Intermittent Explosive DisorderFebruary 2018
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Press Mentions

Alzheimer’s Drug May Improve TrichotillomaniaMarch 9th, 2023
An Alzheimer's Drug Might Ease Hair-Pulling DisorderFebruary 28th, 2023
Illinois Grapples with a Rise in Sports Gambling Problems as Bets Hit $1B a MonthFebruary 12th, 2023
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Grant Support

N-Acetyl Cysteine PLUS Behavioral Therapy For Nicotine Dependent Pathological GamNational Institute On Drug Abuse2009–2010
Cognitive-Behavioral Therapy For Pathological GamblingNational Institute Of Mental Health2005–2008
Cognitive-Behavioral Therapy For Pathological GamblingNational Institute Of Mental Health2004