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75 Francis StDepartment of PathologyBoston, MA 02115
Phone+1 617-732-5500
Dr. Aster is on Doximity
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Education & Training
- Mass General Brigham/Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1987 - 1992
- University of Michigan Medical SchoolClass of 1987
Certifications & Licensure
- MA State Medical License 1991 - 2025
- American Board of Pathology Anatomic Pathology
Publications & Presentations
PubMed
- Integrative cytogenetic and molecular studies unmask "chromosomal mimicry" in hematologic malignancies.Melissa Zhao, Scott Ryall, Samuel J Brody, Amyah C Harris, Kristin Cabral
Blood Advances. 2025-03-11 - 3 citationsA neoantigen vaccine generates antitumour immunity in renal cell carcinoma.David A Braun, Giorgia Moranzoni, Vipheaviny Chea, Bradley A McGregor, Eryn Blass
Nature. 2025-03-01 - Notch induces transcription by stimulating release of paused RNA polymerase II.Julia M Rogers, Claudia A Mimoso, Benjamin J E Martin, Alexandre P Martin, Jon C Aster
Genes & Development. 2024-11-27
Abstracts/Posters
- Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALLJon C. Aster, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALLJon C. Aster, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Other
- Intravascular large cell lymphomaAster JC, Bí_er-Auer A, Freedman AS
http://www.uptodate.com/contents/intravascular-large-cell-lymphoma
UpToDate, Wolters Kluwer Health - 2012-04-05 - Clinical manifestations, pathologic features, and diagnosis of mantle cell lymphomaAster JC, Freedman AS
http://www.uptodate.com/contents/clinical-manifestations-pathologic-features-and-diagnosis-of-mantle
UpToDate, Wolters Kluwer Health - 2013-03-05 - Clinical manifestations, pathologic features, and diagnosis of precursor B cell acute lymphoblastic leukemia/lymphomaAster JC, Freedman AS
http://www.uptodate.com/contents/clinical-manifestations-pathologic-features-and-diagnosis-of-precur
UpToDate, Wolters Kluwer Health - 2013-01-10 - Join now to see all
Press Mentions
- Targeting Notch and EGFR Signaling in Human Mucoepidermoid CarcinomaJanuary 21st, 2021
- Spatial Tumor Analysis Tool Combines Structural Details with Molecular InsightsJune 24th, 2023
Grant Support
- Oncopathology Training ProgramBRIGHAM AND WOMEN'S HOSPITAL2020–2025
- Oncogenic Notch Signaling: Mechanisms Of ActionNational Cancer Institute2006–2010
- Oncogenic Notch SignalingNational Cancer Institute2006–2010
- HematopathologyNational Cancer Institute2006–2010
- Pathogenesis Of Notch LeukemiaNational Cancer Institute2003–2007
- Core--PathologyNational Institute Of Dental &Craniofacial Research2001–2005
- Core--Murine HematopathologyNational Institute Of Diabetes And Digestive And Kidney Diseases2002
- Core--HematopathologyNational Cancer Institute2001–2002
- Pathogenesis Of Notch 1 LeukemiaNational Cancer Institute1999–2002
- Core--Human HematopathologyNational Cancer Institute2000
- Induction Of Lymphoid Leukemia By Tan-1National Cancer Institute1995–1999
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