JohnW.WinkelmanMD

Sleep Medicine

Associate Professor in Psychiatry at Harvard Medical School and chief of the Sleep Disorders Clinical Research Program in the Department of Psychiatry at Massachusetts General Hospital

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Office
55 Fruit St
Boston, MA 02114
Phone+1 617-724-7426

Education & Training

Massachusetts General Hospital/McLean HospitalResidency, Psychiatry, 1988 - 1991
University of California (San Francisco)/Mount ZionInternship, Internal Medicine, 1987 - 1988
Harvard Medical SchoolClass of 1987

Certifications & Licensure

CA State Medical License 1993 - 2027
MA State Medical License 1991 - 2026
ME State Medical License 2021 - 2026
American Board of Psychiatry and Neurology Psychiatry
American Board of Psychiatry and Neurology Sleep Medicine

Clinical Trials

A Double Blind Crossover Trial of Levetiracetam (Keppra®) and Placebo in the Treatment of Restless Legs Syndrome (RLS) Start of enrollment: 2003 Nov 01
Completed
Phase 2
Sleep Loss and Mechanisms of Impaired Glucose Metabolism Start of enrollment: 2006 Mar 01
Completed
Not Applicable
Efficacy and Safety of Topiramate in the Treatment of Sleep-Related Eating Disorder Start of enrollment: 2008 Jan 01
Completed
Early Phase 1
Altered Brain GABA and Glutamate in Restless Legs Syndrome Start of enrollment: 2010 Apr 01
Completed
Switching From Oral Dopamine Agonists to Rotigotine Start of enrollment: 2014 Aug 01
Completed
Phase 4
Butrans for Treatment of Restless Legs Syndrome Start of enrollment: 2014 Apr 01
Withdrawn
Phase 4
Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes Start of enrollment: 2019 Mar 15
Completed
Phase 4
Efficacy of Suvorexant in Patients With Effectively Treated Restless Legs Syndrome and Persistent Chronic Insomnia Start of enrollment: 2021 Aug 12
Completed
Phase 4
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Publications & Presentations

PubMed

Rethinking clinical trials in restless legs syndrome: A roadmap.
Diego Garcia-Borreguero, Jed Black, Christopher J Earley, Stephany Fulda, Birgit Högl
Sleep Medicine Reviews. 2024-10-01
Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline.
John W Winkelman, J Andrew Berkowski, Lourdes M DelRosso, Brian B Koo, Matthew T Scharf
Journal of Clinical Sleep Medicine. 2024-09-26
Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.
John W Winkelman, J Andrew Berkowski, Lourdes M DelRosso, Brian B Koo, Matthew T Scharf
Journal of Clinical Sleep Medicine. 2024-09-26

Other

Nocturnal leg cramps
Winkelman JW
http://www.uptodate.com/contents/nocturnal-leg-cramps
UpToDate, Wolters Kluwer Health - 2013-01-22

Press Mentions

Updated Guidelines for the Treatment of Restless Leg Syndrome: New Research Prompts a Significant Shift in RecommendationsDecember 3rd, 2024
Guidelines Developed for Treatment of Restless Legs SyndromeDecember 3rd, 2024
An RLS Prescription Revolution May Have BegunNovember 20th, 2024
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Grant Support

Eszopiclone To Counteract Adverse Metabolic Consequences Of Primary InsomniaNational Center For Research Resources2007–2008