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Office
7435 21st Ave S
Nashville, TN 37232Phone+1 615-936-6113
Summary
- John M. Stafford, MD., PhD is a physician-scientist at Vanderbilt University medical center whose research focuses on the mechanisms by which obesity and diabetes contribute to risk of non alcoholic fatty liver disease (NAFLD) and cardiovascular disease. Dr. Stafford is an Associate Professor of Medicine, in the Division of Diabetes, Endocrinology and Metabolism, and Molecular Physiology and Biophysics. He is also an investigator and clinician at the Veterans Administration Tennessee Valley Healthcare System. Dr. Stafford completed his MD, PhD training at Vanderbilt University Medical Center, where his graduate studies defined how metabolic signals are coordinated at the level of gene transcription. His medical residency, and fellowship in Endocrinology were also performed at Vanderbilt. Since his appointment to the Vanderbilt faculty in 2008, Dr. Stafford directs an active research program in obesity and lipid metabolism funded by the American Diabetes Association, American Heart Association, The National Institutes of Health, Department of Veterans Affairs, and the John A. Hartford Foundation. This work has revealed important hepatic pathways that lessen the impact of obesity on glucose metabolism and HDL function.
Education & Training
- Vanderbilt University Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 2005 - 2008
- Vanderbilt University Medical CenterResidency, Internal Medicine, 2003 - 2005
- Vanderbilt University School of MedicineClass of 2003
Certifications & Licensure
- TN State Medical License 2005 - 2026
- American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Publications & Presentations
PubMed
- 4 citationsDeficiency of the lipid flippase ATP10A causes diet-induced dyslipidemia in female mice.Adriana C Norris, Eugenia M Yazlovitskaya, Lin Zhu, Bailey S Rose, Jody C May
Biorxiv. 2023-08-14 - 3 citationsATP10A deficiency results in male-specific infertility in mice.Adriana C Norris, Eugenia M Yazlovitskaya, Tzushan Sharon Yang, Alex Mansueto, John M Stafford
Frontiers in Cell and Developmental Biology. 2024-01-01 - 55 citationsThe Molecular Physiology of Hepatic Nuclear Factor 3 in the Regulation of GluconeogenesisJen-Chywan Wang, John M. Stafford, Donald K. Scott, Calum Sutherland, Daryl K. Granner
The Journal of Biological Chemistry. 2000-05-12
Journal Articles
- CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat DietLin Zhu, Thao Luu, Christopher H. Emfinger, Bryan A Parks, Jeanne Shi, Elijah Trefts, Fenghua Zeng, Zsuzsanna Kuklenyik, Raymond C. Harris, David H. Wasserman, Sergio ..., Diabetes, 9/2018
Grant Support
- CETP and Sex-Differences in Metabolic and Cardiovascular DiseaseNIH-NHLBI2019–2024
- Estrogen and coordinated metabolism of carbohydrate and lipids with obesityNIH/NIDDKPresent
Professional Memberships
- Member
- Member
- Member
External Links
- Google Scholarhttps://scholar.google.com/citations?user=rhrZSjEAAAAJ&hl=en
- Lab Websitehttps://medsites.mc.vanderbilt.edu/staffordlab/stafford-lab
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