JohnSarantopoulosMD

Clinical Trials

• Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function Start of enrollment: 2005 Dec 01

  Completed

  Phase 1

• Vorinostat in Treating Patients With Kidney Cancer Start of enrollment: 2005 Oct 01

  Completed

  Phase 2

• Study of Vinorelbine Liposomes Injection for Advanced Solid Tumors, Non-Hodgkin's Lymphoma or Hodgkin's Disease Start of enrollment: 2006 Jul 01

  Completed

  Phase 1

• Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery Start of enrollment: 2008 Oct 01

  Completed

  Phase 1

• BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma Start of enrollment: 2010 Jan 01

  Completed

  Phase 1, Phase 2

• S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery Start of enrollment: 2011 Apr 01

  Active, not recruiting

  Phase 3

• A Phase 1 Trial of ABI-011 in Patients With Advanced Solid Tumors or Lymphomas Start of enrollment: 2011 Mar 01

  Terminated

  Phase 1

• An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function Start of enrollment: 2011 Oct 01

  Completed

  Phase 1

• Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function Start of enrollment: 2011 Nov 01

  Completed

  Phase 1

• Radiation and Cetuximab Plus Intratumoral EGFR Antisense DNA in Locally Advanced Head and Neck Squamous Cell Carcinoma Start of enrollment: 2013 Apr 01

  Completed

  Phase 1, Phase 2

• Phase I Study to Evaluate the Effect of LDE225 on the Pharmacokinetics of Bupropion and Warfarin in Patients Start of enrollment: 2013 Apr 01

  Completed

  Phase 1

• Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma Start of enrollment: 2013 Sep 16

  Active, not recruiting

  Phase 3

• Phase 1b Trial of BGJ398/BYL719 in Solid Tumors Start of enrollment: 2013 Oct 01

  Completed

  Phase 1

• XL999 Administered Intravenously to a Subject With Advanced Malignancies Start of enrollment: 2010 Apr 01

  No longer available

• LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma Start of enrollment: 2014 Jul 23

  Completed

  Phase 2

• Safety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies. Start of enrollment: 2015 Jun 17

  Completed

  Phase 1, Phase 2

• A DDI Study to Assess the Effect of INC280 on the PK of Midazolam and Caffeine in Patients With cMET-dysregulated Advanced Solid Tumors Start of enrollment: 2015 Dec 10

  Completed

  Phase 1

• Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies Start of enrollment: 2015 Nov 23

  Terminated

  Phase 1, Phase 2

• Expanded Access to Everolimus, for an Individual Patient With GIST (Gastrointestinal Stromal Tumors)(CTMS#18-0019)

  Temporarily not available

• Expanded Access to Everolimus, for an Individual Patient With Uterine Sarcoma (CTMS#18-0020)

  Available

• Oral AMXT 1501 Dicaprate in Combination With DFMO Start of enrollment: 2018 Jun 12

  Completed

  Phase 1

• An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors Start of enrollment: 2020 Jun 26

  Recruiting

  Phase 1

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