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Office
UCSD ACTRI, 9452 Medical Center Drive, Ste 2W-108
La Jolla, CA 92037Phone+1 206-909-5475Fax+1 858-657-8557
Education & Training
- Clinical Center at the National Institutes of HealthResidency, Neurology, 1984 - 1986
- Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1983 - 1984
- University of California (San Diego) Medical CenterInternship, Transitional Year, 1979 - 1980
- Mayo Clinic College of MedicineClass of 1979
Certifications & Licensure
- CA State Medical License 2011 - 2025
- WA State Medical License 1985 - 2013
- American Board of Psychiatry and Neurology Neurology
- American Board of Psychiatry and Neurology Clinical Neurophysiology
- American Board of Psychiatry and Neurology Neuromuscular Medicine
Awards, Honors, & Recognition
- Super Doctor SuperDoctors.com
- Top MD Consumers Checkbook
Clinical Trials
- Mexiletine for the Treatment of Muscle Cramps in ALS Start of enrollment: 2013 May 01
- A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS) Start of enrollment: 2021 Sep 02
Roles: Principal Investigator
Publications & Presentations
PubMed
- 305 citationsPremature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.Ze’ev Melamed, Jone López-Erauskin, Michael Baughn, Ouyang Zhang, Kevin Drenner
Nature Neuroscience. 2019-01-14 - 381 citationsControversies and priorities in amyotrophic lateral sclerosisMartin R Turner, Orla Hardiman, Michael Benatar, Benjamin Rix Brooks, Adriano Chiò
The Lancet. Neurology. 2013-03-01 - 738 citationsPathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutationsIan R. A. Mackenzie, Eileen H. Bigio, Paul G. Ince, Felix Geser, Manuela Neumann
Annals of Neurology. 2007-05-01
Journal Articles
- Transcriptome–Pathology Correlation Identifies Interplay Between TDP-43 and the Expression of Its Kinase CK1E in Sporadic ALSJohn Ravits, MD, Acta Neuropathologica
Press Mentions
- ALS-Causative Mutations in FUS/TLS Confer Gain- and Loss-of-Function by Altered Association with SMN and U1-snRNPJanuary 27th, 2020
- Researchers Describe New ALS Biomarkers, Potential New Drug TargetsJuly 16th, 2019
- Restoring Levels of Membralin Protein May Extend Survival in ALS, Mouse Study SuggestsJune 12th, 2019
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Grant Support
- Microgenomic Studies Of ALSNational Institute Of Neurological Disorders And Stroke2006–2007
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