
John Pacella MD
Interventional Cardiology
Associate Professor of Medicine, University of Pittsburgh School of Medicine
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UPMC Heart and Vascular Institute200 Lothrop St Wing 5BPittsburgh, PA 15213
Phone+1 412-647-3087
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Education & Training
- UPMC Medical EducationFellowship, Interventional Cardiology, 2005 - 2006
- UPMC Medical Education/Presbyterian Shadyside HospitalFellowship, Cardiology Clinical Investigator, 2000 - 2005
- UPMC Medical EducationResidency, Internal Medicine, 1998 - 2000
- University of Pittsburgh School of MedicineClass of 1998, MD
- University of PittsburghPremedical, Medicine, 1992 - 1993
- Lehigh UniversityMS, Mechanical Engineering, 1990 - 1992
- Lehigh UniversityM.S., Mechanical Engineering, 1990 - 1992
- Carnegie Mellon UniversityBS, Mechanical Engineering (biomedical emphasis), 1986 - 1990
- Carnegie Mellon UniversityB.S., Mechanical Engineering with Biomedical Emphasis, 1986 - 1990
Certifications & Licensure
- PA State Medical License 1999 - 2026
- American Board of Internal Medicine Cardiovascular Disease
- American Board of Internal Medicine Interventional Cardiology
- American Heart AssociationACLS/BLS
Awards, Honors, & Recognition
- First Prize University of Pittsburgh School of Medicine, 12th Annual Department of Medicine Research Day, 2014
- First Prize (Martin Blomley Best Clinical Poster) 17th European Symposium on Ultrasound Contrast Imaging, 2012
- Award for dedication and talent in the areas of teaching, research, and public service University of Pittsburgh 34th Annual Honors Convocation, 2010
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Clinical Trials
- The PACE-MI Registry Study - Outcomes of Beta-blocker Therapy After Myocardial Infarction (OBTAIN) Start of enrollment: 2009 May 01
- The Dual Antiplatelet Therapy Study (DAPT Study) Start of enrollment: 2009 Oct 01
- Treatment With Adenosine Diphosphate (ADP) Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome Start of enrollment: 2010 Mar 01
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Publications & Presentations
PubMed
- Ischemia/Reperfusion Injury Enhances Accumulation of Perfluoropropane Droplets.Cheng Chen, Shouqiang Li, Terry O Matsunaga, John J Pacella, E Carr Everbach
Ultrasound in Medicine & Biology. 2025-02-01 - Percutaneous coronary intervention for stable late ST-elevation myocardial infarction with symptoms onset between 12 and 72 h - A systematic review.Shumail Fatima, Matthew E Harinstein, Mubashir Hussain, John J Pacella
Cardiovascular Revascularization Medicine. 2024-12-29 - 1 citationsEffect of Ambient Conditions on Acoustic Activation of the Perfluoropropane Droplets Within the Infarct Zone.Shouqiang Li, Cheng Chen, John Lof, Elizabeth A Stolze, Jiri Sklenar
Ultrasound in Medicine & Biology. 2024-08-01
Journal Articles
- Bedside Ultrasound Assessment of Jugular Venous Compliance as a Potential Point-of-Care Method to Predict Acute Decompensated Heart Failure 30-Day ReadmissionSimon MA, Schnatz RG, Romeo JD, Pacella JJ, J Am Heart Assoc, 1/1/2018
- Inertial cavitation ultrasound with microbubbles improves reperfusion efficacy when combined with low dose tissue plasminogen activator in an in-vitro model of microva...Goyal A, Yu FTH, Tenwalde MG, Chen X, Villanueva FS, and Pacella JJ, Ultrasound Med Biol, 1/1/2017
- The role of nitric oxide during sonoreperfusion of microvascular obstructionYu FTH, Chen X, Straub A, Pacella JJ, Theranostics, 1/1/2017
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Books/Book Chapters
Abstracts/Posters
- Sonoreperfusion of Microvascular Obstruction: a step towards clinical translation.Istvanic F, YTH, Chen X, Villanueva FS, Pacella JJ, Multiple Presentations, Multiple Locations, 2017, 2018, 1/1/2018
- The Role of Nitric Oxide During Sonoreperfusion of Microvascular Obstruction.Yu F.T.H., Avula V, Chen X, Straub A., Lavery L, Villanueva F.S. and Pacella JJ, 33nd Annual Advances in Contrast Ultrasound �International Bubble Conference; 22nd European Symposium on Ultrasound Contrast Imaging, Rotterdam, The Netherlands, 2017; Chicago, IL, 2018, 1/1/2018
- Tissue Plasminogen Activator Loaded Microbubbles for the Treatment of Coronary Microvascular Obstruction.D'Auria SJ, Istvanic F, Yu F; Chen X, Pacella JJ, American Heart Association Scientific Sessions, Chicago, IL, 1/1/2018
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Lectures
- The Role of Nitric Oxide during Sonoreperfusion of Microvascular ObstructionUniversity of Pittsburgh, School of Medicine, 2017; Chicago, IL, 2018 - 1/1/2018
- Progress in the treatment of microvascular obstruction using ultrasound and microbubble therapyUniversity of Pittsburgh - 1/1/2015
- Cardiac Catheterization and Coronary StentsCarnegie Mellon University - 1/1/2014
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Press Mentions
- Microvascular Therapeutics Has Received Funds from the National Heart, Lung and Blood Institute (NHLBI)July 19th, 2021
- Microvascular Therapeutics Receives NIH SBIR Phase I Funds for Its Program to Treat Heart AttackJuly 31st, 2020
Committees
- Member, Fellows Research Day Task Force, American Heart Association PA Affiliate 2011 - Present
- Member, Industrial and Professional Advisory Council (IPAC), PennState University 2011 - 2011
- Judge, Fellows Research Day Committee, American Heart Association PA Affiliate 2010 - 2014
Professional Memberships
- Fellow
- Fellow
- Fellow
- Member
- Institute of Electrical and Electronics EngineersMember
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