JohnC.MarshallMD

Endocrinology • Charlottesville, VA

Adrenal Disease, Gonad Disorders & Reproductive, Parathyroid, Pituitary Disorders & Neuroendocrinology

Professor of Medicine, University VA School of Medicine

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Office
415 Ray C Hunt Dr
Ste 2100
Charlottesville, VA 22903
Phone+1 434-924-1825

Fax+1 434-244-9456

Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1973 - 1974
Victoria Univ Manchester- Fac MedClass of 1965

Certifications & Licensure

VA State Medical License 1990 - 2026
MI State Medical License 1977 - 2022
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Endocrinology, Diabetes and Metabolism

Awards, Honors, & Recognition

Outstanding leadership Award Endocrine Society, 2020
Clinical Investigator Award Endocrine Society, 2008
Transatlantic Medal of the Society for Endocrinology Society for Endocrinology, 1997
Clinical Endocrinology Trust Medal Society fo Endocrinology, 1991
Elected Member Association American Physicians, 1987
America's Top Doctors Castle Connolly, 2002-2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
CMS Meaningful Use Stage 1 Certification EpicCare Inpatient - Core EMR, Epic Systems Corporation, 2012
Elected Member The American Society for Clinical Investigation, 1981
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Clinical Trials

Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection Start of enrollment: 2003 Feb 01
Completed
Phase 2
Collaborative H1N1 Adjuvant Treatment Pilot Trial Start of enrollment: 2010 Jan 01
Terminated
Phase 2
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and Stimulation Start of enrollment: 2006 Oct 10
Active, not recruiting
Not Applicable
Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess Start of enrollment: 2018 Jun 01
Withdrawn
Early Phase 1
Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess Start of enrollment: 2018 Jan 19
Withdrawn
Early Phase 1
Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen Overproduction Start of enrollment: 2018 Jun 01
Withdrawn
Early Phase 1
Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess Start of enrollment: 2017 Mar 20
Recruiting
Early Phase 1
Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess Start of enrollment: 2016 Dec 09
Recruiting
Not Applicable
Assessment of the Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition Start of enrollment: 2000 Apr 01
Active, not recruiting
Not Applicable
Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone Start of enrollment: 2009 Feb 18
Completed
Not Applicable
Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by Progesterone Start of enrollment: 2011 Mar 11
Recruiting
Phase 1
Assessment of Sensitivity of the Hypothalamic GnRH Pulse Generator to Estradiol and Progesterone Inhibition Start of enrollment: 2011 Apr 22
Terminated
Not Applicable
Assessment of Day-night Secretion of Progesterone and LH Across Puberty Start of enrollment: 2008 Jul 10
Recruiting
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Publications & Presentations

PubMed

192 citations
Polycystic Ovary Syndrome: Evidence for Reduced Sensitivity of the Gonadotropin-Releasing Hormone Pulse Generator to Inhibition by Estradiol and Progesterone
Carmen L. Pastor, Marie L. Griffin-Korf, Joseph A. Aloi, William S. Evans, John C. Marshall
The Journal of Clinical Endocrinology and Metabolism. 1998-02-01
204 citations
Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome.
John A. Jane, Robert M. Starke, Mohamed A. Elzoghby, Davis L. Reames, Spencer C. Payne
The Journal of Clinical Endocrinology and Metabolism. 2011-06-29
24 citations
Regulation of gonadotropin subunit messenger ribonucleic acid expression by gonadotropin-releasing hormone pulse amplitude in vitro.
Daniel J. Haisenleder, G. A. Ortolano, M Yasin, Alan C. Dalkin, John C. Marshall
Endocrinology. 1993-03-01

Journal Articles

Insulin Resistance, Hyperinsulinemia, and LH: Relative Roles in Peripubertal Obesity-Associated Hyperandrogenemia
Christopher R McCartney, Eleanor G Hutchens, Karen L Knudsen, Jessicah S Collins, John C Marshall, The Journal of Clinical Endocrinology and Metabolism

Grant Support

Project 1 - Testosterone - GNRH Pulse Frequency And The Evolution Of PCOS In AdolEunice Kennedy Shriver National Institute Of Child Health &Human Development2009–2012
Core A - Administrative CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2009–2012
Clinical And Basic Studies In Polycystic Ovarian SyndromeEunice Kennedy Shriver National Institute Of Child Health &Human Development2009–2012
Progesterone And LH Across Puberty In Girls With/Without HyperandrogenemiaNational Center For Research Resources2009–2010
Metformin And Sensitivity Of GNRH Pulse Generator Suppression In HyperandrogemiaNational Center For Research Resources2009–2010
Androgen Blockade And Sensitivity Of The GNRH Pulse GeneratorNational Center For Research Resources2009–2010
Adrenal Androgen Production In Normal And Obese GirlsNational Center For Research Resources2008–2010
Progesterone Inhibition Of GNRH Pulsatility In Adolescent GirlsNational Center For Research Resources2004–2010
Intragonadotrope Pathways Regulating Gene TranscriptionEunice Kennedy Shriver National Institute Of Child Health &Human Development2000–2010
Androgen Receptor CAG Repeat Polymorphism &Hypothalamic Sex Steroid SensitivityNational Center For Research Resources2006–2009
Cellular And Physiological Mechanisms In ReproductionEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–2009
Androgen Receptor CAG Repeat Polymorphism And Serum Androgen In Adolescent GirlsNational Center For Research Resources2007–2008
Nocturnal Secretion Of Ovarian Steroids, LH, And FSH In Adolescent GirlsNational Center For Research Resources2005–2008
Endometrial Function In Polycystic Ovary SyndromeNational Center For Research Resources2004–2008
Clinical &Basic Studies In Polycystic Ovarian SyndromeEunice Kennedy Shriver National Institute Of Child Health &Human Development1998–2008
Admin CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2007
Repeated Courses Of E2 And P In Producing Ovulation In Women With PCOSNational Center For Research Resources2006–2007
Neuroendocrine Regulation Of Ovulation--Studies In PCOSEunice Kennedy Shriver National Institute Of Child Health &Human Development1998–2007
Hypothalamic Opioid TONE In Polycystic Ovary SyndromeNational Center For Research Resources2004–2005
Role Of Progesterone In GNRH Frequency RegulationNational Center For Research Resources2004
Rapidity Of Progesterone Suppression Of LH Pulse FrequencyNational Center For Research Resources2004
Nocturnal Secretion Of Ovarian Steroids, LH, FSH In GirlNational Center For Research Resources2004
Anovulation In Pcos--Etiology Of Increased LH SecretionEunice Kennedy Shriver National Institute Of Child Health &Human Development2003
Hyperinsulinemia And Etiology Of Excess Gnrh/Lh In PCOSNational Center For Research Resources2000–2002
Mid Luteal Estrogen And Medroxyprogesterone Acetate In PCONational Center For Research Resources1998–2002
Flutamide And GNRH Secretion In PCOS And NormalsNational Center For Research Resources1998–2002
Physiological Regulation Of Gonadotropin Gene ExpressionEunice Kennedy Shriver National Institute Of Child Health &Human Development1993–2002
Neuroendocrine Regulation Of Cyclic Ovulation: PCOSEunice Kennedy Shriver National Institute Of Child Health &Human Development1997–2000
Metformin And GNRH Secretion In PCOS And NormalsNational Center For Research Resources1998–1999
Suppression Of LH Pulsatility In Progesterone Dose Response Curve In WomenNational Center For Research Resources1996–1999
Intracellular Regulation Of Gonadotrope Gene ExpressionEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–1999
Physiologic Estrogen &Medroxyprogesterone Acetate Producing OvulationNational Center For Research Resources1997
Center For Cellular &Molecular Studies In ReproductionEunice Kennedy Shriver National Institute Of Child Health &Human Development1997
Suppression Of LH Pulsatility--Progesterone Dose Response Curve Studies In WomenNational Center For Research Resources1994–1995
Suppression Of High Frequency GNRH Pulsatility In Polycystic Ovary DiseaseNational Center For Research Resources1993–1995
Ability Of Exogenous Estradiol And Progesterone To Suppress LH PulsatilityNational Center For Research Resources1993–1995
Role Of Estradiol In The Regulation Of Luteal Phase GNRH FrequencyNational Center For Research Resources1993
Intracellular Regulation Of LH Subunit MRNA ExpressionEunice Kennedy Shriver National Institute Of Child Health &Human Development1991–1992
Regulation Of Gonadotrope Function By Pulsatile GNRHEunice Kennedy Shriver National Institute Of Child Health &Human Development1990–1991
Intracellular Regulation Of LH Subunit MRNA ExpressionEunice Kennedy Shriver National Institute Of Child Health &Human Development1989–1990
Regulation Of Gonadotrope Function By Pulsatile GNRHEunice Kennedy Shriver National Institute Of Child Health &Human Development1987–1990
Training Program In Endocrinology And MetabolismNational Institute Of Diabetes And Digestive And Kidney Diseases1986–1990
Training Program In Endocrinology, Metabolism, And AgingNational Institute On Aging1987–1989
Intracellular Mechanisms Regulating LH SubunitEunice Kennedy Shriver National Institute Of Child Health &Human Development1988
Role Of GNRH In Gonadotropin SecretionEunice Kennedy Shriver National Institute Of Child Health &Human Development1985–1986