John Lucas MD MSCR

Radiation Oncology•Memphis, TN

Pediatric Radiation Oncology

Associate Member, Department of Radiation Oncology, St. Jude Children's Research Hospital

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St. Jude Children's Research Hospital 262 Danny Thomas PlaceRadiation Oncology MS 210, Room I3126Memphis, TN 38103
Phone+1 901-595-3226

Education & Training

Wake Forest University Baptist Medical CenterResidency, Radiation Oncology, 2011 - 2015
University of North Carolina HospitalsInternship, Internal Medicine, 2010 - 2011
Medical University of South CarolinaMS, Clinical and Translational Research, 2010
Medical University of South CarolinaClass of 2009
Erskine CollegeBachelor of Science, Biology & Chemistry, Magna Cum Laude, 2004

Certifications & Licensure

TN State Medical License 2015 - 2027
CA State Medical License 1982 - 2018
TX State Medical License 1996 - 2018
NM State Medical License 1992 - 2017
SC State Medical License 2014 - 2017
AL State Medical License 1975 - 2016
DC State Medical License 2004 - 2016
MD State Medical License 1999 - 2016
NY State Medical License 1979 - 2016
NC State Medical License 2010 - 2015
MA State Medical License 1983 - 2013
American Board of Radiology Radiation Oncology
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Awards, Honors, & Recognition

Student/Resident Research Day Annual Meeting, 2nd Place Poster Presentation South Carolina Medical Association, 2009
Medicine Research Day, 1st Place poster presentation, Medical Student section MUSC, 2009
Head and Neck Multidisciplinary Research Workshop, 1st Place, Pre-doctoral Section Medical University of South Carolina, 2008
Student Research Day, 2nd-place Poster Presentation, PhD II Section Medical University of South Carolina, 2007
Student Research Day, 1st-place Oral Presentation, Clinical Professional and Masters, Basic Science II Section Medical University of South Carolina, 2005-2006
Outstanding Research Undergraduate Student in Molecular Biology South Carolina Academy of Science Award, 2003
E.L. Reid Awards in Chemistry 2002
Dr. Calvin Reid Pre-Medical Scholarship in Biology 2002
Summer Undergraduate Research Program MUSC, 2002
Scholar-in-Training Award American Association for Cancer Research, 2007
Edith Peng Excellence in Cancer Research Endowment Award Hollings Cancer Center, 2007
Annie and Charles H. Fair Scholarship South Carolina Medical Association, 2005
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Clinical Trials

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) Start of enrollment: 2018 May 14
ACTIVE_NOT_RECRUITING
PHASE3
Evaluation of Proton Therapy in Pediatric Cancer Patients Start of enrollment: 2017 Aug 01
ACTIVE_NOT_RECRUITING
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations Start of enrollment: 2018 Nov 06
ACTIVE_NOT_RECRUITING
PHASE2
Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17 Start of enrollment: 2018 Dec 12
RECRUITING
PHASE2
A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors Start of enrollment: 2022 May 10
RECRUITING
PHASE3
Haploidentical HCT for Severe Aplastic Anemia Start of enrollment: 2021 Jan 21
RECRUITING
PHASE2
Erlotinib and Surgery in Treating Patients With Head and Neck Cancer That Can Be Removed by Surgery Start of enrollment: 2008 Mar 01
Completed
Early Phase 1
Intensity-Modulated Radiation Therapy, Pemetrexed, and Erlotinib in Treating Patients With Recurrent or Second Primary Head and Neck Cancer Start of enrollment: 2008 Mar 01
Terminated
Phase 1, Phase 2
A Study to Give Treatment Inside the Eye to Treat Retinoblastoma Start of enrollment: 2022 Nov 04
RECRUITING
PHASE2
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma Start of enrollment: 2024 Apr 19
RECRUITING
PHASE3
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Publications & Presentations

PubMed

Perception of infertility risk vs. objective fertility status in males exposed to alkylating agents but not radiation therapy: a report from the St. Jude Lifetime (SJL...
Megan E Ware, Raymond K We, William H Kutteh, Rachel T Webster, Angela Delaney
Journal of Cancer Survivorship. 2025-04-02
Phase 2 Trial of Veliparib, Local Irradiation and Temozolomide in Patients with Newly Diagnosed High-Grade Glioma: A Children's Oncology Group Study.
Matthias A Karajannis, Arzu Onar-Thomas, Tong Lin, Patricia A Baxter, Daniel R Boué
Neuro-Oncology. 2024-11-19
Development of the pediatric neuro-oncology services assessment aid: An assessment tool for pediatric neuro-oncology service delivery capacity.
Revathi Rajagopal, Rosdali Diaz Coronado, Syed Ahmer Hamid, Regina Navarro Martin Del Campo, Frederick Boop
Neuro-Oncology Advances. 2024-10-04

Abstracts/Posters

Impact of Competing Treatment Scenarios on Lifetime Disease Burden and Quality Adjusted Life Expectancy (QALE) Among Survivors of High-Risk Childhood Hodgkin Lymphoma ...
John T. Lucas Jr., 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019

Lectures

Speaking Hodgkin
University of Alabama, Birmingham, AL - 2020
Comprehensive molecular Characterization of Pediatric Treatment-Induced High-Grade Glioma: A Distinct Entity… Despite Disparate Etiologies”.
NBTP, St. Jude Children’s Research Hospital. - 2019
Proton Therapy at St. Jude Children’s Research Hospital: Updates on Outcomes and Toxicity
NBTP Research Retreat, St. Jude Children’s Research Hospital. - 2019
DICE-y Decision Making During Multi-Modality Care in Cancer Predisposition Syndromes: Pleuropulmonary Blastoma as an Exemplar in Pediatric Oncology
St. Jude Children’s Research Hospital. - 2019
Pediatric Oncology: Updates from Around the World
Asia Pacific Tumor Board - Cure4Kids. - 2019
Pediatric Malignancies: CNS & Cardiopulmonary Toxicities and Outcomes
ASTRO Annual Meeting as a Discussant in an Oral Scientific Session, Chicago, IL. - 2019
Selection of Local and Adjunctive Therapies at Relapse in Pleuropulmonary Blastoma - Balancing Risks and Benefits
ASPHO, DICER1 Symptosium, New Orleans, LA. - 2019
Patterns of Failure in Patients with Medulloblastoma Treated on SJMB03
Children’s Oncology Group Fall Meeting. Dallas, Texas. - 2018
The Evolving Role of Radiotherapy in Wilms Tumor
ASTRO Annual Meeting, San Antonio, TX. - 2018
Treatment failure patterns across medulloblastoma subgroups on SJMB03, a prospective trial of risk-adapted, volume-reduced radiation therapy and dose-intense chemothe...
Neurobiology and Brain Tumor Program - St. Jude Children’s Research Hospital - 2018
The Evolving Role of Radiotherapy in Wilms Tumor
ASTRO Annual Meeting, San Diego, CA - 2017
Management of Metastatic Disease in Rhabdomyosarcoma
CTRST - St. Jude Children’s Research Hospital, Memphis, TN - 2017
Radiotherapy in Pediatric Oncology- Radiobiology, Physics, Complications, and Second Cancers
Hematology and Oncology Fellows Conference - St. Jude Children’s Research Hospital, Memphis, TN - 2017
Visually Accessible Rembrandt Imaging (VASARI) Features Predict Survival and Identify Distinct Groups of Pediatric High Grade Glioma
Radiologic Society of North America, Chicago, IL. - 2017
Role of radiotherapy in metastatic disease in Neuroblastoma
Pediatric Radiation Oncology Society, Manhattan, NY. - 2017
Neuro-Endocrine Complications of Pediatric Brain Tumors: Anticipated benefits of a systematic approach to diagnosis and improvements in radiotherapy delivery
Clinical Translational Research in Solid Tumors - St. Jude Children’s Research Hospital, Memphis, TN - 2017
Role of Cranial Radiotherapy in Pediatric Lymphomas with CNS Involvement
LLHBMTCT - St. Jude Children’s Research Hospital, Memphis, TN. - 2016
Clinical challenges of low-risk rhabdomyosarcoma of the female genital tract
CTRSTC - St. Jude Children’s Research Hospital, Memphis, TN. - 2016
Biomarkers in Pediatric Oncology
University of Alabama, Birmingham, AL. - 2016
The Evolving Role of Radiotherapy in Wilms Tumor
ASTRO Annual Meeting, Boston, MA. - 2016
MET-PET Delineates Non-Contrast Enhancing Tumor (nCET) Regions at High Risk for Recurrence in Pediatric High Grade Glioma
ISPNO Liverpool, United Kingdom. - 2016
Proton Radiotherapy in Pediatric Malignancies
Wake Forest University, Winston Salem, NC. - 2016
Radiotherapy and ADT in High Risk Prostate Cancer”. Prostate Cancer – Challenges and Solutions: Second Annual Symposium.
Wake Forest University, Winston Salem, NC. - 2014
Brain Metastasis Research: The Cutting Edge of Radiosurgery at Wake Forest.
Brain Tumor Center of Excellence. September 20, 2013. Wake Forest Baptist Health, Winston Salem, NC. - 2013
A Competing Risk Analysis of Neurologic vs Non-Neurologic Death in Patients Undergoing Radiosurgical Salvage Following Whole Brain Radiotherapy Failure (WBRT): Who Act...
ASTRO Annual Meeting 2013. Atlanta, GA. September 22-25th - 2013
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Authored Content

Reviewer ProfileDecember 2021

Grant Support

Translational Research Fellow - T32NIH2008–2009
Paul Calabresi FellowThe Paul Calabresi Research Fellowship (PhRMA Foundation)2006–2007
Summer Health Professionals Research (SHRP) FellowMUSC2005

Committees

Member, Provider Advisory Council 2019 - Present
Member, Radiation Safety Committee 2015 - Present
Member, Diagnostic Biomarkers Shared Resource Oversight Committee 2015 - Present