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Office
UH Rainbow Babies and Children's Hospital
11100 Euclid Ave Department of Pediatrics-Hematology and Oncology
Cleveland, OH 44106Phone+1 216-844-7700Fax+1 216-844-5431
Education & Training
- Case Western Reserve Univ/Univ Hosps Cleveland Med Ctr/Rainbow Babies and Childrens HospitalResidency, Pediatrics, 1987 - 1990
- Ohio State University College of MedicineClass of 1987
Certifications & Licensure
- OH State Medical License 2007 - 2026
- MD State Medical License 1990 - 2008
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2014
Publications & Presentations
PubMed
- 76 citationsHereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.Carolyn A. Felix, Marion M. Nau, Takashi Takahashi, Tetsuya Mitsudomi, Itsuo Chiba
The Journal of Clinical Investigation. 1992-02-01 - 1467 citationsREGULATION OF IMMUNE RESPONSES BY TGF-β*John J. Letterio, Anita B. Roberts
Annual Review of Immunology. 1998-04-01 - 369 citationsAlex's Lemonade stand foundation infant and childhood primary brain and central nervous system tumors diagnosed in the United States in 2007-2011Quinn T. Ostrom, Peter de Blank, Carol Kruchko, Claire M. Petersen, Peter Liao
Neuro-Oncology. 2015-01-01
Abstracts/Posters
- Preclinical Studies and Phase I Trial of Vactosertib in Combination with Pomalidomide in Relapsed Multiple Myeloma: A Corticosteroid-Free Approach By Targeting TGF-_ S...John Letterio, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Lectures
- Vactosertib, a TGF-ß Receptor I Kinase/ALK5 Inhibitor, Diminishes Tumor Progression and Bone Disease in a Mouse Model of Multiple Myeloma and Overcomes Resistance to P...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Preclinical Studies and a Phase I Trial of the TGF-β Receptor Inhibitor, Vactosertib (TEW-7197), in Combination with Pomalidomide in Patients with Multiple Myeloma Ref...2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Press Mentions
- National Experts Map Out Adolescent and Young Adult (AYA) Cancer Research AgendaDecember 5th, 2017
- St. Baldrick's Head Shaving for Cancer Research at Rainbow Babies & Children's HospitalMarch 10th, 2017
- Colon Cancer in Millennials? Two Cleveland Area Women Warning Others About Rare DiagnosisDecember 27th, 2016
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Grant Support
- Discovery And Evaluation Of Novel Triterpenoid Chemopreventives In A New Colon CANational Cancer Institute2008–2009
- Tgf-Beta1 In Hematopoietic And Immune Cell DifferentiatiDivision Of Basic Sciences - Nci2002–2004
- Tgf-Beta1 In Hematopoietic &Immune Cell DifferentiationDivision Of Basic Sciences - Nci2003
- Tgf-Beta1: Hematopoietic And Immune Cell DifferentiationDivision Of Basic Sciences - Nci2001
- Tgf-Beta1 In Hematopoietic And Immune Cell Differentiation And FunctionDivision Of Basic Sciences - Nci1999–2000
- TGF Beta In Hematopoietic And Immune Cell Differentiation And FunctionDivision Of Basic Sciences - Nci1996–1998
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