John LHoMD

PubMed

• 114 citations
  Down-Modulation of Lung Immune Responses by Interleukin-10 and Transforming Growth Factor β (TGF-β) and Analysis of TGF-β Receptors I and II in Active Tuberculosis
  M. Glória Bonecini-Almeida, John L. Ho, Neio Boechat, Richard C. Huard, Sadhana Chitale
  Infection and Immunity. 2004-05-01
• 200 citations
  PCR-based method to differentiate the subspecies of the Mycobacterium tuberculosis complex on the basis of genomic deletions
  Richard C. Huard, Luiz Claudio Oliveira Lazzarini, W. Ray Butler, Dick van Soolingen, John L. Ho
  Journal of Clinical Microbiology. 2003-04-01
• 52 citations
  Granulocyte-Macrophage and Macrophage Colony-Stimulating Factors Activate Intramacrophage Killing of Leishmania mexicana amazonensis
  John L. Ho, S. G. Reed, E. A. Wick, M. Giordano
  The Journal of Infectious Diseases. 1990-07-01

Journal Articles

• What are TB program and vaccine approaches to control global TB? (editorial)  
  Ho JL, J Pulmon Resp Med, 1/1/2012
• Mycobacterium tuberculosis spoligotypes that may derive from mixed strain infections revealed by a novel computational approach  
  Lazzarini LCO, Rosenfeld J, Huard RC, Hill V, Lapa e Silva JR, DeSalle R, Rastogi N, Ho JL, Infection, Genetics and Evolution (MEEGID: J Mol Epi and Evol Genetics of Infect Dis), 8/2/2011
• Tuberculosis in New York City Caused by RDRio Mycobacterium tuberculosis Lineage Shows Distinct Epidemiological Features And Clinical Attributes  
  Weisenberg SA, Gibson AL, Kurepina N, Heejung Bang, Huard RC, Lazzarini LC, Li J, Clark CM, Agerton T, Driscoll J, Kreisworth B, Munsiff SS, and Ho JL, Infection, Genetics and Evolution (MEEGID: J Mol Epi and Evol Genetics of Infect Dis), 8/2/2011
• Oral Pentoxifylline Combined With Pentavalent Antimony: A Randomized Trial In Mucosal Leishmaniasis  
  Machado PRL, Lessa H, Lessa M, Guimaraes LH, Bang H, Ho JL, Carvalho EM, Clin Infect Dis, 3/1/2007
• Low expression of antigen-presenting and costimulatory molecules by lung cells from tuberculosis patients  
  Flores-Batista VC, Boechat N, Lago PM, Lazzarini LC, Pessanha LR, Almeida AS, Mafort TT, Kritski AL, Ho JL, Lapa-e-Silva JR, Brazilian J Med Biological Res, 1/1/2007
• High level expression of recombinant Mycobacterium tuberculosis culture filtrate protein CFP32 in Pichia pastoris  
  Benabdesselem C, Barbouche MR, Jarboui MA, Dellagi K, Ho JL, Fathallah DM, Molecular Biotechnology, 1/1/2007
• Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within specific members of the PE_PGRS gene subfamily  
  Karboul A, Gey van Pittius NC, Namouchi A, Vincent V, Sola C, Rastogi N, Suffys P, Fabre M, Cataldi A, Huard RC, Kurepina NE, Kreiswirth BN, Ho JL, Gutierrez CM and Ma..., BMC Evolutionary Biology, 12/1/2006
• Enhanced patient serum immunoreactivity to recombinant Mycobacterium tuberculosis CFP32 produced in the yeast Pichia pastoris: potential for the serodiagnosis of tuber...  
  Benabdessalem C, Fathallah DM, Huard RC, Zhu H-x, Jarboui MA, Koussay D, Ho JL, and Barbouche RM, J Clinical Microbiology, 1/1/2006
• HTLV-1 Modifies the clinical and immunological response of schistosomiasis  
  Porto AF, Santos SB, Alcantara L, Guerreiro JB, Passos J, Gonzalez T, Neva F, Gonzalez D, De Jesus AR, Ho JL, Carvalho EM, Clin Exp Immunol, 1/1/2004
• Down-modulation of lung immune response by IL-10 and TGF-Beta ligands and TGF-Beta receptors I and II in active tuberculosis  
  Bonecini Almeida MG, Ho JL, Boechat N, Huard RC, Chitale S, Doo H, Geng J, Lorena Rego L, Lazzarini LCOD, Kritski AL, Johnson, Jr, WD, Macaffrey T, Lapa e Silva JR, Infect & Immun, 1/1/2004
• Induction of in vitro human macrophage anti-Mycobacterium tuberculosis activity: requirement for IFN-gamma and primed lymphocytes  
  Bonecini-Almeida MG, Chitale S, Boutsikakis I, Geng J, Doo H, He S, Ho JL, J Immunol, 5/1/1998
• Differential effects of interleukin-12, interleukin-15, and interleukin-2 on human immunodeficiency virus type 1 replication in vitro  
  Bayard-McNeeley M, Doo H, He S, Hafner A, Johnson WD Jr, Ho JL, Clin Diagn Lab Immunol, 9/1/1996
• The influence of coinfections on HIV transmission and disease progression  
  Ho JL, The AIDS Reader, 7/1/1996
• Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis  
  Nicholson, S, Bonecini-Almeida G, Lapa e Silva JR, Nathan C, Xie Q-w, Mumford R, Weidner JR, Calaycay J, Geng J-y, Boechat N, Linhares C, Rom W, Ho JL, J Exp Med, 5/1/1996
• Neutrophils from human immunodeficiency virus (HIV)-uninfected donors induce HIV replication from mononuclear cells of HIV-infected patients: an in vitro model of HIV ...  
  Ho JL, He SH, Hu AH, Basile F, Saito AY, Laurence J, Johnson, Jr. WD, J Exp Med, 1/1/1995
• Cytokines in the treatment of leishmaniasis: from studies of immunopathology to patient therapy  
  Ho JL, Badaro R, Hatzigeogiou D, Reed SG, Johnson Jr W.D., Biotherapy, 1/1/1994
• rhGM-CSF reverses neutropenia and reduces secondary infection in visceral leishmaniasis  
  Badaro R, Nasimento C, Carvalho JS, Badaro F, Russo D, Ho JL, Reed SG, Johnson Jr., WD, Jones TJ, J Infect Dis, 1/1/1994
• A rapid and reliable assay to enumerate CD4 T-lymphocyte in whole blood  
  Ferreira OC, Suleiman G, Brites C, Novoa P, Piovesana M, Suleiman J, Kanayama RH, Russel TR, Zwerner R, Harrington Jr. W, Ho JL, J AIDS, 1/1/1994
• Rapid culture and quantitation of human immunodeficiency virus type-1 (HIV-1) from patient cells without the use of mitogen-stimulated donor cells  
  Kim PK, He SH, Ho JL, Clin & Diag Lab Immunol, 1/1/1994
• Granulocyte-macrophage colony-stimulating factor in combination with pentavalent antimony for the treatment of visceral Leishmaniasis  
  Badaro R, Nascimento C, Carvalho JS, Badaro F, Russo D, Ho JL, Reed SG, Johnson WD Jr, Jones TC, Eur J Clin Microbiol Infect Dis, 1/1/1994
• Interleukin-4 receptor signaling in human monocytes and U937 cells involves the activation of phosphatidylcholine specific phospholipase C A comparison with chemotacti...  
  Ho JL, Zhu BX, He SH, Du Bao, Rothman R, J Exp Med, 1/1/1994
• Genetic heterogeneity of the principal neutralizing determinant of the human immunodeficiency virus type-1 in Brazil  
  Potts KE, Kalish M, Lott T, Orloff G, Bernard MA, Alves CB, Badaro R, Lou CC, Suleiman J, Ferreira O, Schochetman G, Johnson WD, Ou CY, Ho JL, AIDS, 1/1/1993
• Interleukin-6 down modulates cytokine activation of macrophage antileishmanial activity and oxidative capacity  
  Hatzigeogiou D, He SH, Sobol J, Grabstein K, Ho JL, J Immunol, 1/1/1993
• A prospective study of HIV-seropositive asymptomatic women of childbearing age in a developing country  
  Deschamps MM, Pape JW, Desvareaux M, Williams-Russo P, Madhavan S, Ho JL, Johnson WD, Jr, J AIDS, 1/1/1993
• Effect of isoniazid prophylaxis on the incidence of active tuberculosis and progression of HIV infection  
  Pape JW, Jean S, Ho JL, Hafner A, Johnson WD, Jr, Lancet, 1/1/1993
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Books/Book Chapters

• Current Topics on the Profiles of Host Immunological Response to Mycobacterium tuberculosis 
  Chapter: Immunosuppressive state in the lung response to Mycobacterium tuberculosis. 
  Page 167 - 182Lapa e Silva JR, Almeida AS, Boechat N, Flores-Batista VL, Lago PM, Lazzarini LC, Kritski AL, Huard RC, Ho JLResearch Signpost, Kerala, India2009
• Textbook of Infectious Diseases 
  Chapter: Leishmaniasis. 
  Page 2308 - 2326Ho JL, and Johnson WDEditors: Gorbach S.Lippincott, Williams & Wilkins, New York, NYEdition 3rd,2004
• The Lung: Scientific Foundations 
  Chapter: Defenses of the Lung Against Tuberculosis. 
  Page 2381 - 2394Ho JL, and Riley LWEditors: R. Crystal, J. West, E. Weibel, and P. Barnes.Edition 2nd,1997
• Conn's Current Therapy 
  Chapter: Tularemia. 
  Page 128 - 129Laraque F, Ho JLSaunders Co., Philadelphia, PA1992
• Internal Medicine 
  Chapter: Gram-Positive aerobic bacillary infections: Corynebacterium and Listeria. 
  Page 1452 - 1454Johnson Jr W.D, Ho JLEditors: Stein J.H..Little, Brown and Co., BostonEdition 3rd,1990
• Phagocytes and Diseases 
  Chapter: Antimicrobial functions of macrophages. 
  Page 59 - 90Ho JLEditors: MS Klempner, B Styrt, JL Ho.MTP Press Limited, Lancaster, U.K. and Hingham, MA1989
• Phagocytes and Diseases 
  Chapter: Interaction between antimicrobial agents and phagocytes. 
  Page 119 - 144Styrt B, Ho JL, Klempner M.S.Editors: MS Klempner, B Styrt, JL Ho.MTP Press Limited, Lancaster, U.K. and Hingham, MA1989
• Conn's Current Therapy 
  Chapter: Food Poisoning. 
  Ho JLW.B. Saunders Co., Philadelphia1988
• Current Clinical Topics in Infectious Diseases 
  Chapter: Therapy of Intraabdominal sepsis due to colonic perforation. 
  Page 266 - 295Tally FP, Ho JLEditors: JS Remington, MN Swartz.McGraw-Hill, Inc., New York1987
• Infectious Diseases in the Female Patient 
  Chapter: Antimicrobial therapy and resistance to antimicrobial agents. 
  Page 72 - 105Ho JL, Barza MEditors: R.P. Galask.Springer-Verlag, New York1986
• Principles of Medical Therapy in Pregnancy 
  Chapter: An approach to infectious diseases. 
  Page 381 - 392Ho JL, Barza MEditors: R. Gleicher.Plenum Publishing Corporation, New York1985
• Principles of Medical Therapy in Pregnancy 
  Chapter: Chemotherapy of infection. 
  Page 406 - 419Ho JL, Barza MEditors: R. Gleicher.Plenum Publishing Corporation, New York1985
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Abstracts/Posters

• Computational Analysis of the Mycobacterium tuberculosis International Spoligotyping Database Suggests That Certain Spoligopatterns Maybe Derived From Mixed Infection.
  Lazzarini L.C., Huard R., Rosenfeld J., Gibson A., Virgilio M., Gomes H., Lapa e Silva J.R., Suffys P., DeSalle R., and Ho J.L., American Journal of Respiratory and Critical Care Med, 1/1/2008
• "Tuberculosis Caused by Mycobacterium tuberculosis RDRio Genotype Is Associated With A Higher Frequency Of Pulmonary Cavitation"
  Lazzarini L.C., Spindola S., Gibson A., Bang H., Weisenberg S., and Ho J.L., American Journal of Respiratory and Critical Care Medicine, ATS 2008 Meeting, 1/1/2008
• Tuberculosis Caused by Mycobacterium tuberculosis RDRio Genotype Is Associated With A Higher Frequency Of Pulmonary Cavitation.
  Lazzarini LC, Spindola S, Gibson A, Bang H, Weisenberg S, Ho JL, American Thoracic Society Annual Meeting, 1/1/2008
• 3Dimenisonal Molecular Modeling and Comparison of Human and Chimpanzee Toll-Like Receptor 2.
  Brinkworth JF and Ho JL, Evolution, Health, & Disease, 20th Annual International Symposium Center For Study Of Gene Structure & Function, Am Association for Physical Anthropologist, 2007 Annual Meeting, Hunter College, City University Of New York; Philadelphia, PA, 1/19/2007
• Increased levels of IL-10 at the End of Anti-TB (TB) Chemotherapy Is a Marker of Relapse.
  Lago PM, Boechat N, Lazzarini L, Flores-Batista VC, Mafort TT, Kritski A, Ho JL, Lapa e Silva JR, Am J Respir Crit Care Med, 1/1/2007
• Skin Test Conversion and Abnormal Chest X-Ray in Close Contacts of Patients Infected with Different M. tuberculosis Spoligotype Families.
  Noboa R, Barbosa C, Lazzarini L, Boechat N, Leung J, Gomes H, Mafort T, Oliveira M, Ho JL, Kritski A, Suffys P, Lapa e Silva JR, Am J Respir Crit Care Med, 1/1/2007
• Is the Severity of tuberculosis Different When Patients Are Infected by strains of M. tuberculosis Belonging to Diverse Spoligotyping Families?
  Barbosa C, Noboa R, Lazzarini L, Boechat N, Leung J, Elias A, Suffys P, Kritski A, Lapa e Silva JR, Ho JL, Am J Respir Crit Care Med, 1/1/2007
• Infection with Multiples Mycobacterium tuberculosis strains Could Lead to a False Interpretation of the Genotyping Methods.
  Lazzarini L, Huard RC, Boechat N, Virginio MJ, Suffys PN, Lapa e Silva JR, Ho JL, Am J Respir Crit Care Med, 1/1/2007
• Select HIV-1 Strains Activate Innate Immune Inflammatory Response Via CD14 and Toll-Like Receptor 2 by a Viral Gag Protein-Dependent Mechanism.
  Zhu H, Huard R, Huang J, Nociari M, He T, Zerria K, He Y, Chen Z, Jiang S, Golenbock D, and Ho JL, XVI International AIDS Conference, Toronto, Canada, 8/17/2006
• Analysis Of Immunomodulatory Molecules In Lung Cells Of Tuberculosis Patients Before And After Chemotherapy.
  Almeida AS, Boechat N., Lago PM, Flores-Batista VC, Almeida AS, Nociari M, Perez-Sweney B, Huard RC, Lapa E Silva JR, Ho JL, American Journal of Respiratory and Critical Care Med, American Thoracic Society International Conference, San Diego, 1/1/2006
• M. tuberculosis Strains Harboring a Novel Large Chromosomal Deletion (RDRio) Are Infectious, Transmissible and the Predominant Cause of Tuberculosis in Rio de Janeiro,...
  Lazzarini L., R. Huard, N. Boechat, J.R. Lapa e Silva, J. L. Ho, Proc. Am Thor. Soc, 1/1/2005
• Cytokine Profile Expression In The Lung Cells Of Active Tuberculosis Patients During Standard Anti-TB Chemotherapy.
  Almeida AS, Boechat N, Lago PM, Santos AR, Nociari M, Perez-Sweney B, Huard RC, Ho JL, Lapa E Silva, JR, XXIII Congresso Brasileiro De Microbiologia, Santos, 1/1/2005
• Cytokine Expression In The Lungs Of Tuberculous Patients Before And After Standard Chemotherapy.
  Almeida AS, Boechat N, Lago PM, Santos AR, Nociari M, Perez-Sweeney, B, Huard RC., Ho JL, Lapa E Silva, JR, Proc. Am Thor Soc, ATS 2005 San Diego-International Conference American Thoracic Society 100th Anniversary, San Diego, 1/1/2005
• Cytokine Expression In The Lung Of Tuberculous Patient Before And After Standard Chemotherapy.
  Almeida AS, Boechat N, Lago PM, Batista VCSF, Santos AR, Nociari M, Perez-Sweney, B, Huard RC., Ho,JL, Lapa E Silva JR, XXX Meeting Of The Brazilian Society Of Immunology, Sao Pedro, 1/1/2005
• Role of Regulatory Cytokines and Inducible Nitric Oxide Synthase in Active Tuberculosis.
  P. M. Lago, V.C. Flores, L.O. Rego, J. L. Ho, J. R. Lapa e Silva, Proc. Am Thor. Soc., 1/1/2005
• Identification of M. tuberculosis harboring a novel chromosomal deletion: implication to clinical assessment, epidemiology and pathogenesis.
  Lazzarini LC, Huard RC, Boechat N, Mello FQ, Suffys P, Lapa e Silva JR, Ho JL, 42nd Annual Meeting of Infectious Disease Society of America Program, 1/1/2005
• Cytokine Expression In The Lungs Of Tuberculous Patients Before And After Standard Chemotherapy.
  Almeida AS, Boechat N, Lago PM, Santos AR, Nociari M, Perez-Sweeney B, Huard RC, Ho JL, Lapa E Silva JR, Ii Sao Paulo Research Conference-Mechanism Of Infection And Vaccines, Sao Paulo, 1/1/2004
• PCR-based genotypic evaluation of M. tuberculosis isolates from Rio de Janeiro, Brazil.
  Lazzarini de Oliveira LC, Huard RC, Marisco AG, Lapa e Silva JR, Ho JL, Am J Resp Critical Care Med, 1/1/2004
• Transforming growth factor (TGF)-Beta ligand and receptors in pulmonary tuberculosis.
  Lapa e Silva JR, Chitale S, Geng J, Doo H, Rego L, Morgado I, Boechat N, Kritski A, McCaffrey T, Ho JL, Am. J. Respir. & Crit. Care Med., 1998 ALA/ATS International Conference, Chicago, IL, 4/24/1998
• Granuloma formation defect in lymph node of HIV 1 tuberculosis patients.
  Nicol AF, Serapiao MJ, Veloso VG, Cuzzi Maia T, Ho JL, Lapa e Silva JR, Am. J. Respir. & Crit. Care Med., 1998 ALA/ATS International Conference, Chicago, IL, 4/24/1998
• Phenotype of alveolar mononuclear phagocytes from HIV 1 infected patients with active tuberculosis.
  Rego L, Boechat N, Linhares C, Morgado I, Lago P, Kritski A, Ho JL, Lapa e Silva JR, Am. J. Respir. & Crit. Care Med., 1998 ALA/ATS International Conference, Chicago, IL, 4/24/1998
• Expression of HLA-DR by alveolar macrophages from affected areas of tuberculosis patients co-infected with HIV.
  Lapa e Silva JR, Rego L, Linhares C, Boechat N, Rego L, Kritski AL, Ho JL, Am. J. Respir. & Crit. Care Med., 1997 ALA/ATS International Conference, San Francisco, CA, 5/17/1997
• Boechat N, Linhares C, Rego L, Morgado I, Doo H, Gomez KC, Kritski A, Ho JL, Lapa e Silva JR, Am. J. Respir. & Crit. Care Med., 1997 ALA/ATS International Conference, San Francisco, CA, 5/17/1997
• Inducible nitric oxide synthase and cytokine expression in lung cells from patients with tuberculosis.
  Bonecini-Almeida MG, Lapa e Silva JR, Nicholson S, Geng J, Boechat N, Linhares L, Rego L, Kritski A, Ho JL, Am. J. Respir. Crit. Care Med., 1/1/1997
• Cytokine expression in lung cells from patients with tuberculosis and AIDS.
  Lapa e Silva JR, Bonecini Almeida MG, Geng J, Boechat N, Linhares L, Rego L, Lago P, Fonseca A, Costa FB, Kritski A, Ho JL, Am. J. Respir. Crit. Care Med., 1/1/1997
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Other

• The Recently Discovered RDRio Sublineage of the Latin American Mediterranean Spoligofamily: Global Distribution and Potential Host Adaptation. 
  Ho JL, Lazzarini LCO, Huard RC, Gibson AL, Weisenberg S, Kurepina N, Marsico AG, Kreiswirth BN, Kritski AL, Suffys PN, and Lapa e Silva JR, LusoAmerican Foundation
  1/1/2008