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Office
5 E 98th St
New York, NY 10029Phone+1 212-659-8060Fax+1 212-241-2064
Summary
- I am Chief of the Hepatology and Vice Chair of Faculty Affairs in the Jack and Lucy Clark Department of Pediatrics at the Icahn School of Medicine at Mount Sinai and the Kravis Children's Hospital at Mount Sinai. I also serve as the Director of Solid Organ Transplant Outreach for the Recananti- Miller Transplant Institute. My primary clinical focus is transplant Hepatology and I am board certified in pediatric gastroenterology with a certificate of added qualification in transplant hepatology. My goal is for children with liver disease to live full, meaningful lives. I have been fortunate to experience and be part of the tremendous innovations in care for children with complex and serious liver disease. When I started my career, children with serious liver disease had few options and many died before age 5 years. Now, we have medical and surgical treatments including liver transplantation that have revolutionized our approach. My research efforts have focused on the challenges along the path of the patient to sustained heath including but not limited to wait list management, mitigation of complications and ensuring long term allograft health without complications of immunosuppression. Along the way, I established collaborations and relations with clinical and research leaders both inside and outside the US. I have been equally fortunate with the opportunity to integrate these efforts with learnings from other industries. In 2002, I underwent training in improvement science which in turn combined with my traditional research training gave me the tools to meet my goal. Through learning from patient and family experience and collaborations with colleagues outside of medicine at MIT, Harvard Business School and with urban architects, I gained a better understanding of how diversity of knowledge, team effectiveness, communication and decision-making can make care better and guide researc.
Education & Training
- Cincinnati Children's Hospital Medical CenterResidency, Pediatrics, 1982 - 1986
- Massachusetts General HospitalResidency, Pediatrics, 1978 - 1982
- Harvard Medical SchoolClass of 1978
- Harvard CollegeA.B., Magna Cum Laude, 1970 - 1974
Certifications & Licensure
- NY State Medical License 2018 - 2025
- OH State Medical License 1982 - 2019
- American Board of Pediatrics Pediatrics
Awards, Honors, & Recognition
- Fellow American Society of Transplantation, 2019
- Top Doctor Castle Connolly
- Fellow American Association for the Study of Liver Disease, 2015
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Clinical Trials
- Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients Start of enrollment: 2012 Aug 14
- Improving Medication-taking After Liver Transplant Start of enrollment: 2014 Aug 01
Publications & Presentations
PubMed
- Progress and challenges in assessing allograft health in liver transplantation.Jaime Chu, John Bucuvalas
Liver Transplantation. 2024-10-29 - Cytomegalovirus (CMV) Prophylaxis in Pediatric Liver Transplantation (PLT): A Comparison of Strategies Across the SPLIT Consortium.Elizabeth D Knackstedt, Sarah G Anderson, Ravinder Anand, Jeff Mitchell, Ronen Arnon
American Journal of Transplantation. 2024-10-03 - 1 citationsCaregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multicenter SOCIAL-Tx study.Sharad I Wadhwani, Alejandra Alvarado, Holly P Shifman, Bethany Bautista, Jared Yalung
Liver Transplantation. 2024-07-01
Journal Articles
- Frailty in Children with Liver Disease: A Prospective Multicenter StudyLurz,E, Quammie C, Englesbe M, Alonso EM, Lin HC, Hsu EK, Furuya KN, Gupta NA, Venkat VL, Daniel JF, Leonis MA, Miloh T, Telega GW, Yap J, Menendez J, Book LS, Himes R..., J Pediatr, 1/1/2018
- The Medication Level Variability Index (MLVI) Predicts Poor Liver Transplant Outcomes: A Prospective Multi-Site StudyShemesh, E., Bucuvalas, J. C., Anand, R., Mazariegos, G. V., Alonso, E. M., Venick, R. S., ...Shneider, B. L., American Journal of Transplantation, 1/1/2017
- Self-Management Measurement And Prediction Of Clinical Outcomes In Pediatric TransplantAnnunziato, R. A., Bucuvalas, J. C., Yin, W., Anand, R., Alonso, E. M., Mazariegos, G. V., . . Shemesh, E., J Pediatr, 1/1/2017
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Books/Book Chapters
Lectures
- Development of NIH-sponsored consortium for pediatric liver disease1/1/2017
- Metabolic Liver Disease- What, Why and When1/1/2015
- Multi-organ Dysfunction Associated with Pediatric Liver Failure and Solid Organ Transplantation1/1/2015
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Press Mentions
- Low-Resource Neighborhoods Linked to Higher Risk for Pediatric NAFLDNovember 5th, 2022
- Dynamics of Systemic Inflammation as a Function of Developmental Stage in Pediatric Acute Liver FailureJanuary 15th, 2021
- Hepatotoxicity Following Administration of Onasemnogene Abeparvovec (AVXS-101) for the Treatment of Spinal Muscular AtrophyNovember 10th, 2020
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Grant Support
- Immunosuppression Withdrawal for Stable Pediatric Liver Transplant RecipientsNIAID2012–2014
- Medical Adherence in Children Who Had a Liver TransplantNIDDK2009–2014
- Calcineurin Inhibitor Minimization And FOXP3+ Tregs Post-TransplantNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2010
- Biliary Atresia Study (BASIC)National Center For Research Resources2007–2008
- Biliary Atresia Research Consortium DatabaseNational Center For Research Resources2005–2008
- Effect Of IGF-1 On Malnourished Children With Cystic FibrosisNational Center For Research Resources1996–2001
Committees
- Liver and Intestine Committee, UNOS 2013 - 2015
- Associate Editor, Clinical Liver Disease 2012 - 2017
- Editorial Board, Heptology 2012 - 2017
- Pediatric Committee, UNOS 2012 - 2015
- Member, Transplant Hepatology Committee, American Board of Pediatrics 2004 - 2011
- Member, Pediatric Gastroenterology Subboard, American Board of Pediatrics 2001 - 2007
Professional Memberships
- Member
- American Association for the Study of Liver DiseaseFellow
- American Society of TransplantationMember
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