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Office
725 Albany St
# Shapiro
Boston, MA 02118Phone+1 617-638-7480Fax+1 617-638-7486
Education & Training
- Boston University Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 1987 - 1991
- University of California (San Diego) Medical CenterResidency, Internal Medicine, 1985 - 1985
- Case Western Reserve University/University Hospitals Cleveland Medical CenterInternship, Internal Medicine, 1983 - 1984
- Case Western Reserve University School of MedicineClass of 1983
Certifications & Licensure
- MA State Medical License 1987 - 2025
- OH State Medical License 1986 - 1990
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- America's Top Doctors Castle Connolly, 2010-2014
- Boston Magazine Castle Connolly, 2009-2013
- Super Doctor SuperDoctors.com
Clinical Trials
- The Effect of Diflunisal on Familial Amyloidosis Start of enrollment: 2006 Feb 01
- Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis Start of enrollment: 2010 Nov 01
- Safety and Effect of Doxycycline in Patients With Amyloidosis Start of enrollment: 2012 Jul 01
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Publications & Presentations
PubMed
- 6 citationsCharacterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.Felix J Tsai, Luke T Nelson, Gabriel M Kline, Marcus Jäger, John L Berk
Amyloid. 2023-06-01 - 1 citationsAn additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis.Tatiana Prokaeva, Elena S Klimtchuk, Polina Feschenko, Brian Spencer, Haili Cui
Amyloid. 2023-06-01 - 8 citationsImpact of baseline polyneuropathy severity on patisiran treatment outcomes in the APOLLO trial.Dianna Quan, Laura Obici, John L Berk, Yukio Ando, Emre Aldinc
Amyloid. 2023-03-01
Journal Articles
- Unusual Duplication Mutation in a Surface Loop of Human Transthyretin Leads to an Aggressive Drug-Resistant Amyloid DiseaseJohn L Berk, Paul J Kurtin, Proceedings of the National Academy of Sciences
- Inotersen Treatment for Patients with Hereditary Transthyretin AmyloidosisWilliam J Litchy, Peter D Gorevic, Morie A Gertz, Amil M Shah, John L Berk, Peter J Dyck, The New England Journal of Medicine
- Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin AmyloidosisPeter J Dyck, John L Berk, The New England Journal of Medicine
Press Mentions
- Faculty Promotions Announced, May 2021August 17th, 2021
- Intellia, with First Results, Delivers a 'Landmark' for CRISPR Gene EditingJune 26th, 2021
- Hear from the Experts on Hereditary AmyloidosisJune 3rd, 2019
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Grant Support
- Effect Of Diflunisal (IND68092) On Familial AmyloidosisNational Institute Of Neurological Disorders And Stroke2005–2009
- The Effect Of Diflunisal On Hereditary AmyloidosisNational Center For Research Resources2007
- Effect Of Diflunisal On Familial AmyloidosisFood And Drug Administration2006–2007
- Adrenal Insufficiency In Primary Systemic AmyloidosisNational Center For Research Resources1999–2001
- Retinoids And Collagen Transcription In Lung FibroblastsNational Heart, Lung, And Blood Institute1996–1999
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