JohnRBartholomewMD

Internal Medicine • Cleveland, OH

Vascular Medicine, Hematology/Oncology

Professor, Medicine, Case Western Reserve University School of Medicine

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Office
9500 Euclid Ave
Cleveland, OH 44195
Phone+1 800-223-2273

Summary

My primary practice is vascular medicine. My major interests include thrombophilia, the new oral anticoagulants and anticoagulation medications in general. My other interests include the acute treamtent of venous and arterial thrombosis as well as long term management of patients with chronic venous insufficiency. Other interests include the management of patients with a swollen limb including lymphedema and lipedema. I also have a strong interest in peripheral arterial disease. I run the thrombosis center at Cleveland Clinic and have an IVC filter retrieval clinic.

Education & Training

Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 1984 - 1986
University of Maryland Medical Center Midtown CampusResidency, Internal Medicine, 1980 - 1984
Universidad Autonoma de GuadalajaraClass of 1978
Central Michigan UniversityNo Degree, 1972 - 1974
Central Michigan UniversityBS, 1966 - 1970

Certifications & Licensure

OH State Medical License 1988 - 2025
MI State Medical License 1984 - 2021
NY State Medical License 2004 - 2015
MD State Medical License 1981 - 1990
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Award: In Recognition of National Leadership in Vascular Medicine Cleveland Clinic, 2015
Regional Top Doctor Castle Connolly, 2014
CEO Award VTE Prevention Team, 2014
Miller Award (Master Clinician) Cleveland Clinic, 2012
Awarded Master Clinician Society for Vascular Medicine, 2012
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011, 2013
Voted one of Cleveland’s Best Doctors Cleveland Magazine, 2002, 2004, 2006
Teacher of the Year Department of Vascular Medicine, Cleveland Clinic Hospital, 2001
Instructor of the Year - Family Practice Residency St. Joseph Hospital, Michigan State University, 1987
The William Bell, M.D. Award for Patient Care Johns Hopkins Hospital, 1984
Master Clinician Cleveland Clinic
Voted one of Clevelands Best Doctors Cleveland Magazine
Fellow (FACC) American College of Cardiology
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Clinical Trials

Arixtra PE Study- Outpatient Management of Stable Acute Pulmonary Embolism: Once Daily Subcutaneous Fondaparinux Start of enrollment: 2006 Aug 01
Withdrawn
Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis Start of enrollment: 2009 Nov 01
Completed
Phase 3

Publications & Presentations

PubMed

65 citations
A Direct Comparison of Early and Late Outcomes With Three Approaches to Carotid Revascularization and Open Heart Surgery
Mehdi H. Shishehbor, Sridhar Venkatachalam, Zhiyuan Sun, Jeevanantham Rajeswaran, Samir R. Kapadia
Journal of the American College of Cardiology. 2013-11-19
43 citations
Who Should Get Extended Thromboprophylaxis After Bariatric Surgery?: A Risk Assessment Tool to Guide Indications for Post-discharge Pharmacoprophylaxis.
Ali Aminian, Amin Andalib, Zhamak Khorgami, Derrick Cetin, Bartolome Burguera
Annals of Surgery. 2017-01-01
20 citations
Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19.
Aditya Sahai, Rohan Bhandari, Matthew Godwin, Thomas M. McIntyre, Mina K. Chung
Vascular Medicine. 2021-05-19

Journal Articles

Retrograde pulmonary embolectomy for acute pulmonary embolism: A simplified technique
Hussain ST, Bartholomew JR, Leacche M, Zhen-Yu Tong M., Ann Thorac Surg, 1/1/2017
Who should get extended thromboprophylaxis after bariatric surgery? A risk assessment tool to guide indications for post-discharge pharmacoprophylaxis
Aminian A, Brethauer S, Schauer P, Burguera B, Cetin D, Bartholomew JR, Ann Surg, 1/1/2017
Presidential address: 27th Annual Scientific Sessions of the Society for Vascular Medicine: Long Beach, California, June 17, 2016
Bartholomew JR., Vasc Med, 1/1/2016
Centralizing care of cancer-associated thromboembolism: The Cleveland Clinic experience
Rabinovich E, Bartholomew JR, Wilks ML, Tripp BM, McCrae KR, Khorana AA, Thromb Research, 1/1/2016
Managing extended oral anticoagulation after unprovoked venous thromboembolism
Lee Joseph, Bartholomew JR, J Cardiovasc Pharmacol Therapeutics, 1/1/2016
The association of post-exercise ankle:brachial index with cardiovascular outcomes, lower extremity revascularization, and all-cause mortality
Hammad TA, Strefling JA, Zellers PR, Reed GW, Venkatachalam S, Gornik HL, Bartholomew JR, Blackstone EH, Shishehbor MH, JACC, 1/1/2015
Inferior vena cava occlusion causing syncope during upper extremity exertion treated with iliocaval venous revascularization
Hardy DM, Bartholomew JR, Park WM, J Vasc Surg Cases, 1/1/2015
Bivalirudin for the treatment of patients with confirmed or suspected heparin-induced thrombocytopenia
Joseph L, Casanegra AI, Dhariwal N, Smith MA, Raju M, Militello M, Gomes MP, Gornik HL, Bartholomew JR, J Thromb Haemost., 1/1/2014
A Direct Comparison of Early and Late Outcomes with Three Approaches to Carotid Revascularization and Open Heart Surgery
Shishehbor MH, Venkatachalam S, Sun Z, Rajeswaran J, Kapadia SR, Bajzer C, Gornik HL, Gray BH, Bartholomew JR, Clair DG, Sabik JF, Blackstone EH, J Am Coll Cardiol, 1/1/2013
Retrievability and device related complications of the G2 filter: A retrospective study of 139 filter retrievals
Zhu X, Tam MD, Bartholomew J, Newman JS, Sands MJ, Wang W., JVIR, 1/1/2011
A randomized open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-...
Boyce SW, Bandyk DF, Bartholomew JR, Frame JN and Rice L., Am J Therapeutics, 1/1/2011
Carotid artery pseudoaneurysm
Ayoub, K, Nacion, K, Bartholomew, JR, J Vascular Ultrasound, 1/1/2010
A comparison of desirudin and argatroban for suspected heparin-induced thrombocytopenia with or without thrombosis: rationale and design of the PREVENT-HIT study
Frame JN, Rice L, Bartholomew JR, Whelton A, Clinical Therapeutics, 1/1/2010
Case Study: Venous Thoracic Outlet Syndrome Diagnosed Using Duplex Ultrasound
Pacheco H, Yesenko S, Gornik HL, Sakarwala A, Bartholomew JR, J Vasc Ultrasound, 1/1/2009
Heparin induced thrombocytopenia with thrombosis after endovascular aortic aneurysm repair
Kolluri R, Rocha-Singh K, Sarac T, and Bartholomew JR, Vascular and Endovascular Surgery, 1/1/2009
Findings of brain death with the use of carotid duplex ultrasonography
Yesenko SL, Gornik HL, Henion D, Bartholomew JR, Journal of Vascular Ultrasound, 1/1/2008
Rectal sheath hematoma
Osinbowale O, Bartholomew JR, Vascular Medicine, 1/1/2008
Venous thromboembolism prophylaxis in hospitalized heart failure patients
Jois-Bilowich P, Glauser J, Michota F, Bartholomew JR, Diercks D, Weber J, Fonarow GC, Emerman CL, Peacock WF IV, Journal of Cardiac Failure, 1/1/2008
Cigarette smoking and cardiovascular disease
Fish J and Bartholomew JR, Current Cardiovascular Risk Reports, 1/1/2007
Argatroban Anticoagulation for heparin-induced thrombocytopenia in elderly patients
Bartholomew JR, Pietrangeli CE, Hursting MJ, Drugs & Aging, 1/1/2007
Pathophysiology of peripheral arterial disease and risk factors for its development
Bartholomew JR, Olin, JW, Cleveland Clinic Journal of Medicine, 1/1/2006
Today’s Approach to the Treatment of Heparin-Induced Thrombocytopenia
Joseph D, Bartholomew JR, The Journal of Respiratory Diseases, 1/1/2006
Varicose Veins
Bartholomew JR, King T Vidimos AT., Phlebology Digest, 1/1/2006
Varicose Veins
Bartholomew JR, King T, Sahgal A, Vidimos AT., The Cleveland Clinic Journal of Medicine., 1/1/2005
Atheromatous Embolization
Liew YP, Bartholomew JR., Vascular Medicine, 1/1/2005
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Books/Book Chapters

Goldman’s-Cecil Medicine
Chapter: Welcome and manuscript guidelines
Jaff MR, Bartholomew JRElsevier, Philadelphia, PAEdition 26th,2017
Goldman’s-Cecil Medicine
Chapter: Other peripheral arterial diseases
Page 504.0 - 511.0Jaff MR, Bartholomew JRPhiladelphia, PA2016
Consultative Thrombosis and Hemostasis.
Editors: Licthin, Bartholomew JR.Springer Publishing Company, New York, NY2013
An atlas of clinical vascular medicine
Chapter: An atlas of clinical vascular medicine
Bartholomew JREditors: Mintz J, Mintz BL, Jaff MR.Wiley Blackwell, Hoboken, NJ2013
Dean and Satiani/Color Atlas and Synopsis of Vascular Medicine
Chapter: Heparin, low-molecular weight heparin and warfarin skin necrosis
Sharma, A, Bartholomew, JRMcGraw-Hill2013
Rutherford’s Vascular Surgery
Chapter: Atheromatous embolization
Olin JW, Bartholomew JREditors: Jack L. Cronenwett MD and Wayne Johnston.Saunders Elsevier, Philadelphia, PAEdition 8th,2013
Consultative Thrombosis and Hemostasis
Chapter: Heparin-induced thrombocytopenia
Bartholomew JREditors: Lichtin A and Bartholomew JR.Springer Publishing Company, New York, NY2013
Perioperative Management of the Patient with Rheumatic Disease
Chapter: Perioperative Management of Anticoagulation in the Patient with the Antiphospholipid Syndrome in Cardiac Surgery and Cardiac Interventions
Bartholomew, JREditors: Mandell, BF.Springer, New York, NY2012
Vascular Disease: Diagnostic and Therapeutic Approaches
Chapter: Vasospastic diseases
Page 371.0 - 387.0Kolluri R, Bartholomew JREditors: Jaff MR, White C.Cardiotext Publishing, Minneapolis, MN2011
Vascular Disease: Diagnostic and Therapeutic Approaches
Chapter: Environmental and hereditary vascular disorders.
Page 547.0 - 559.0Lokhandwala J, Bartholomew JREditors: Jaff MR, White C.Cardiotext Publishing, Minneapolis, MN2011
Current Clinical Medicine
Chapter: Peripheral arterial disease
Page 196.0 - 204.0AlSolaiman F, AlMahameed A, Bartholomew JRSaunders Elsevier, Philadelphia, PA2010
Current Clinical Medicine
Chapter: Venous thromboembolism.
Page 205.0 - 2011.Kim SH, Bartholomew JREditors: Carey WD.Saunders Elsevier, Philadelphia, PA2010
Antithrombotic Drug Therapy in Cardiovascular Disease (Contemporary Cardiology)
Chapter: Venous thromboembolism.
Kim E and Bartholomew JREditors: Lincoff M and Askari A.Humana Press2009
Manual of Cardiovascular Medicine
Chapter: Venous thromboembolism and hypercoagulable states.
Kim E, Nambi V, Bartholomew JREditors: Griffin P Griffin, Eric J Topol.Lippincott, Williams and WilkinsEdition 3rd,2009
Adult Clinical Cardiology Self Assessment Program-7
Chapter: Uncommon Vascular Disorders
Gornik HL, Kolluri R, Bartholomew JR.American College of Cardiology, Bethesda, MD2009
Antithrombotic Drug Therapy in Cardiovascular Disease (Contemporary Cardiology).
Chapter: Heparin-induced thrombocytopenia
Bartholomew JR.Editors: Lincoff M and Askari A.Humana Press2009
Adult Clinical Cardiology Self Assessment Program-8
Chapter: Uncommon Vascular Disorders
Gornik H, Kolluri R, Bartholomew JR.American College of Cardiology, Bethesda, MD2008
Immunogenicity of Biopharmaceuticals
Chapter: Heparin-Induced Thrombocytopenia.
Celestin C and Bartholomew JREditors: van de Weert, M and Moller EH.Springer, New York2008
Current Treatment Options in Cardiovascular Medicine
Chapter: Heparin-induced thrombocytopenia. An update. 2007.
Bartholomew JREditors: Creager, MA.2008
Heparin-Induced Thrombocytopenia
Chapter: Bivalirudin for the treatment of heparin-induced thrombocytopenia.
Bartholomew JREditors: Warkentin TE, Greinacher A.Marcel Dekker, Inc.Edition 4th,2007
Vascular Medicine and Endovascular Interventions.
Chapter: Unusual Vascular Disorders.
Page 124.0 - 140.0Bartholomew, JREditors: Rooke TW, Sullivan TM, Jaff MR.Blackwell Futura2007
Comprehensive Hospital Medicine
Chapter: Peripheral Arterial Disease.
Page 255.0 - 262.0Kalsi H, Bartholomew JR, Williams M, Hayward R., Flanders S., et al.Editors: Mark V. Williams, M.D., F.A.C.P,.Saunders Elsevier2007
Textbook of Cardiovascular Medicine
Chapter: Disease of Peripheral Vessels
Page 1531. - 1548.AlMahameed A, Bartholomew JREditors: Eric J. Topol, M.D..Lippincott, Williams & Wilkins, PhiladelphiaEdition 3rd,2006
Pharmacological Therapies for Peripheral Vascular Diseases
Chapter: Deep Venous Thrombosis / Pulmonary Embolism Pharmaco Therapy.
Page 139.0 - 162.0Joseph D, Bartholomew JREditors: Debabrata Mukherjee.Taylor & Francis, London2005
Adult Clinic Cardiology Self Assessment Program-6
Chapter: Uncommon Vascular Disorders
Kolluri R, Bartholomew, JR.American College of Cardiology2005
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Abstracts/Posters

Highlights of the SVM 25th Anniversary and Scientific Sessions.
Bartholomew JR, Vasc Med, Society for Vascular Medicine, LaJolla, CA, 1/1/2014
Bivalirudin for the treatment of heparin-induced thrombocytopenia: A 9 year, 461 patient experience.
Joseph L, Gornik HG, Bartholomew JR, ACC, Washington, D.C., 1/1/2014
The impact of combined IR/Vascular Medicine IVC filter clinic on filter retrieval and prevention of chronic venous insufficiency.
Brancatelli S, Bartholomew JR, Geisinger M, Sands MJ, McLennan G, SIR 38th Annual Scientific Meeting, New Orleans, LA, 1/1/2013
New take on an old story: Revisiting the heparin nomogram.
Hamilton A, Patrick R, Militello M, Bartholomew JR, Phillips S, Society of Hospital Medicine, Atlanta, GA, 1/1/2013
Prevalence and risk factors for present on admission deep venous thrombosis among patients with cardiovascular disease transferred to a tertiary care center.
Strong AT, Rajeswaran J, Bartholomew JR, Blackstone E, Anabila M, Clair DG, Khot UN, Goepfarth P, Lytle BW, Nissen SE, Connor Phillips, S, Poria N, Sabik JF, Svensson ..., Society for Vascular Medicine, Cleveland, OH, 1/1/2013
Misclassification of DVT (deep vein thrombosis) and PE (pulmonary embolism) and the effect on perceived length of stay (LOS)
Perez A, Bartholomew, JR, Society for Vascular Medicine, Minneapolis, MN, 1/1/2012
High prevalence of present on admission DVT among patients transferred to a tertiary cardiovascular center may lead to over reporting of adverse quality indicators.
Sharma AM, Rajeswaran J, Sanghani R, Bartholomew JR, Blackstone E, Doehring C, Goepfarth P, Grattan A, Khot U, Phillips S, Zhong J, Gornik HL, Society for Vascular Medicine, Minneapolis, MN, 1/1/2012
Revisiting the heparin nomogram: leveraging technology to improve quality
Hamilton AC, Bartholomew JR, Militello M, Patrick R, Phillips S, American Society of Hematology, Atlanta, GA, 1/1/2012
External carotid artery plaque independently predicts mortality in patients without internal carotid artery atherosclerosis
Marycz D, Archinal D, Gornik HL, Bartholomew JR, Shishehbor MH, Kim SH, ACC, Chicago, IL, 1/1/2011
Association between peripheral arterial disease (PAD), functional capacity and all-cause mortality
Yousefzai R, Gornik HL, Batizy LH, Soo Kim E, Cerqueira MD, Jaber WA, Houghtaling PL, Venkatachalam S, Gray BH, Bartholomew JR, Blackstone EH, Shishehbor MH, ACC, Chicago, IL, 1/1/2011
Severe thrombocytopenia caused by protamine-dependent platelet antibodies
Sullivan MJ, Singla A, Kapadia S, Bartholomew JR, Aster RH, Curtis BR., AABB Annual Meeting & CTTXPO, San Diego, CA, 1/1/2011
Carotid artery pseudoaneurysm.
Ayoub, K, Nacion, K, Bartholomew, JR, 33rd Annual Meeting of the Society for Vascular Ultrasound, Boston, MA, 1/1/2010
Venous Thoracic Outlet Syndrome Diagnosed Using Duplex Ultrasonography.
Pacheco, H, Yesenko, S, Gornik, H, Abizer, S, Bartholomew, JR, 31st Annual Meeting of the Society for Vascular Ultrasound, San Diego, CA, 1/1/2008
Ultrasound-guided thrombin injection for the treatment of iatrogenic upper extremity pseudoaneurysm.
Moghbelli M, Begelman SM, Bartholomew JR, AlMahameed A, Carman T, Joseph D, Garcia B, Whitelaw S, Gornik HL, American College of Physicians, New Orleans, 1/1/2007
Identifying Lower Extremity Venous Aneurysms with Duplex Ultrasonography.
Henion, D, Black, S, Gornik, H, Yesenko, S, Bartholomew, JR., 30th Annual Meeting of the Society for Vascular Ultrasound, 1/1/2007
Novel risk factors for deep vein thrombosis in hospitalized patients.
Jaffer AK, Mady E, Mallick S, Tadros R, Sekhon A, Bartholomew J, Brotman DJ, International Society of Thrombosis and Haemostasis, Geneva, Switzerland, 1/1/2007
Association of PF4 and thromboembolism in patient with heparin induced thrombocytopenia
Rashid, A, AlSolaiman F, Joseph D, Carman T, Gornik HL, Bartholomew, JR, Society for Vascular Medicine and Biology, Baltimore, MD, 1/1/2007
Characteristics of an outpatient vascular medicine practice at an academic medical center.
AlSolaiman, F, Alsayegh L, Bartholomew JR, Gornik HL, Society for Vascular Medicine and Biology, Baltimore, MD, 1/1/2007
The Safety of Triple Oral Antithrombotic Therapy with Aspirin, Clopidogrel, and Warfarin after Coronary Stent Placement.
Lee JS, AlMahameed A, Hong MS, Bartholomew JR, Ellis SG, Bhatt DL., 1/1/2006
Medical and Endovascular Therapy for Stoke Complicating Cerebral Venous Thrombosis: The Cleveland Clinic Experience.
Russman AN, Frost N, AlMahameed A, Bartholomew J R, Sila CA., International Stroke Conference., 1/1/2006
Green Plasma, Arterial Thrombosis and Thrombophilia.
Alsayegh LG, Carman TL, Bartholomew JR, Kashyap VS, Koo AP., American Society for Apheresis, Las Vegas, 1/1/2006
Combined effect of eGFR and ABI on mortality.
Liew YP, Bartholomew JR, Schreiber MJ., Society for Vascular Medicine and Biology, Philadelphia, PA, 1/1/2006
Argatroban anticoagulation for heparin-induced thrombocytopenia in elderly patients.
Bartholomew JR, Pietrangeli CE, Hursting MJ., American Society of Hematology, 1/1/2006
Bivalirudin in Patients with HIT or Clinically Suspected HIT.
Ramirez LM, Carman T L, Begelman S M, AlMahameed A, Joseph D, Kashyap VS, White, D A, Andersen-Harris K, Bartholomew, J R., American Society of Hematology, 1/1/2005
Argatroban Dosage in Critically Ill Patients with HIT.
Baghdasarian, SB, Singh I, Militello M, Bartholomew JR, Begelman SB, The American Society of Hematology, San Diego, California, 1/1/2004
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Lectures

13th Annual Intensive Board Review of Cardiology Four-Day Symposium
Cleveland Clinic - Cleveland, Ohio / The Cleveland Clinic Foundation, Cleveland, Ohio - 8/19/2012

Other

Geriatric Times
Bartholomew JR, Messinger-Rapport B, Cleveland Clinic Medicine Institute
1/1/2013
Case Study: A 55-year-old male with recent lower extremity revascularization and leg blisters.
Widmer RJ, Gornik HL, Bartholomew JR., Society for Vascular Medicine
http://www.vascularmed.org/case_studies/case.cfm?id=220