Joern-HendrikWeitkampMDFAAP

PubMed

• Safety and Efficacy of a Composite Lipid Emulsion with Fish Oil in Hospitalized Neonates and Infants Requiring Prolonged Parenteral Nutrition - A Randomized, Double-Bl...
  Steven A Abrams, Kimberly D Ernst, Joern-Hendrik Weitkamp, Maria Mascarenhas, Ann Anderson-Berry
  The Journal of Nutrition. 2024-12-01
• Success and opportunities of the American Academy of Pediatrics Marshall Klaus research grant program in neonatal-perinatal medicine.
  Albertina Lee, Joern-Hendrik Weitkamp, Angie Tune, Jim Couto, Krithika Lingappan
  Journal of Perinatology. 2024-10-05
• Opportunistic dried blood spot sampling validates and optimizes a pediatric population pharmacokinetic model of metronidazole.
  Rachel L Randell, Stephen J Balevic, Rachel G Greenberg, Michael Cohen-Wolkowiez, Elizabeth J Thompson
  Antimicrobial Agents and Chemotherapy. 2024-04-03

Journal Articles

• Heart Rate Characteristic index monitoring for blood stream infection in an NICU: A 3-year experience  
  Coggins SA, Weitkamp JH, Grunwald L, Stark AR, Reese JJ, Walsh W, Wynn JL, Arch Dis Child Fetal Neonatal Ed, 1/1/2016
• Maternal influences on fetal microbial colonization and immune development  
  Romano-Keeler J, Weitkamp JH, Pediatr Res, 1/1/2015
• SIGNEC UK and the second international conference on necrotizing enterocolitis  
  Kashu M, Infant, 1/1/2015
• Oligodendroglial maldevelopment in the cerebellum after postnatal hyperoxia and its prevention by minocycline  
  Scheuer T, Brockmoller V, Blanco Knowlton M, Weitkamp JH, Ruhwedel T, Müller S, Endesfelder S, Bührer C, Schmitz T, Glia, 1/1/2015
• Infectious causes for necrotizing enterocolitis  
  Coggins S, Wynn, J, Weitkamp JH, Clin Perinatol, 1/1/2015
• More than a gut feeling: Predicting surgical necrotizing enterocolitis  
  Weitkamp JH, Gut, 1/1/2014
• Early life establishment of site-specific microbial communities in the gut  
  Romano-Keeler J, Moore DJ, Brucker R, Lovvorn H, Wang C, Tang YW, Bordenstein S, George AL, Weitkamp JH, Gut Microbes, 1/1/2014
• CD8aa+ innate-type lymphocytes in the intestinal epithelium mediate mucosal immunity  
  Van Kaer L, Algood HMS, Singh K, Parekh VV, Greer MJ, Piazuelo MB, Weitkamp JH, Matta P, Chaturvedi R, Wilson KT, Olivares-Villagomez D, Immunity, 1/1/2014
• Medical decision support using machine learning for early detection of late onset neonatal sepsis  
  Mani S, Ozdas A, Aliferis, C, Varol HA, Chen Q, Carnevale R, Chen Y, Romano-Keeler J, Weitkamp JH, J Am Med Inform Assoc, 1/1/2014
• Congenital radiocontrast agent in the neonatal gut  
  Huang TK, Reese J, Weitkamp JH, Stancombe BB, J Pediatr, 1/1/2014
• Incidence of catheter related bloodstream infections in neonates following removal of peripherally inserted central venous catheters  
  Casner, M, Hoesli, SJ, Slaughter JC, Hill ML, Weitkamp JH, Pediatr Crit Care Med, 1/1/2014
• Small intestinal intraepithelial TCRAlphaBeta lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis  
  Weitkamp JH, Rosen MJ, Zhiguo Z, Koyama T, Denning T, Rock MT, Moore DJ, Matta P, Denning PW, PLoS One, 1/1/2014
• Use of a computerized C-reactive protein (CRP)-based sepsis evaluation protocol in the NICU: a five year experience  
  Coggins S, Wynn JL, Hill ML, Slaughter JC, Ozdas A, Waitman LR, Carnevale RJ, Weitkamp JH, PLoS One, 1/1/2013
• Abnormal heart rate characteristics prior to clinical diagnosis of necrotizing enterocolitis  
  Stone M, Attridge J, Tatum P, Weitkamp JH, Mukherjee A, Lake D, Moorman R, McGahren ED, Rodgers B, Fairchild K, J Perinatol, 1/1/2013
• STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines  
  Rosen MJ, Chaturvedi R Washington MK, Kuhnheim LA, Moore PD, Coggeshall SS, McDonough EM, Weitkamp JH, Singh AB, Coburn LA, Williams CS, Van Kaer L, Peebles RS, Wilson KT, J Immunol, 1/1/2013
• SIGNEC UK and the first international conference on necrotizing enterocolitis  
  Kashu M, Infant, 1/1/2013
• Necrotizing enterocolitis is characterized by disrupted immune regulation and diminished mucosal regulatory (FOXP3+) / effector (CD4+, CD8+) T cell ratios  
  Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel JA, Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore DJ, Polk DB, Gut, 1/1/2013
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  Namachivayam K, Blanco CL, Mohankumar K, Jagadeeswaran R, Vasquez M, McGill-Vargas L, Garzon SA, Jain SK, Gill RK, Freitag NE, Weitkamp JH, Seidner SR, Maheshwari A, Am J Physiol Gastrointest Liver Physio, 1/1/2013
• Safety and efficacy of meropenem in infants with suspected or complicated intra-abdominal infections  
  Cohen-Wolkowiez M, Castro LM, Poindexter B, Bidegain M, Weitkamp JH, Schelonka R, Ward R, Wade KC, Valencia G, Burchfield D, Arrieta A, Bhatt-Mehta V, Walsh M, Kantak ..., Clin Infect Dis, 1/1/2012
• Transactivation of EGFR by LPS induces COX-2 expression in enterocytes  
  McElroy SJ, Hobbs S, Kallen M, Rosen MJ, Grishin A, Matta P, Upperman J, Ford H, Polk DB, Weitkamp JH, PLoS One, 1/1/2012
• Cytomegalovirus infection  
  Plosa E, Esbenshade J, Fuller P, Weitkamp JH, Pediatr Rev, 1/1/2012
• Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis  
  Ullrich T, Tang YW, Correa H, Garzon SA, Maheshwari A, Hill M, Matta P, Krishnan MK, Weitkamp JH, Pediatr Infect Dis J, 1/1/2012
• Mapping the new world of necrotizing enterocolitis: review and opinion  
  Gordon PV, Christensen R, Weitkamp JH, Maheshwari A, e-JNR, 1/1/2012
• Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in immature murine small intestine  
  Zhang C, Sherman MP, Prince LS, Bader D, Weitkamp JH, Slaughter JC, McElroy SJ, Dis Model Mech, 1/1/2012
• Regulatory properties of the intestinal microbiome effecting the development and treatment of diabetes  
  Romano-Keeler J, Weitkamp JH, Moore DJ, Curr Opin Endocrinol Diabetes Obes, 1/1/2012
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Books/Book Chapters

• Manual of Neonatal Care 
  Chapter: Chapter 27. Necrotizing enterocolitis. 
  Weitkamp JH, Premkumar MH, Martin CREditors: Hansen AR, Eichenwald EC, Stark AR, Martin CR.Lipincott-Raven Inc., Philadelphia, PAEdition 8th,2016
• New Challenges Foetal and Neonatal Infections 
  Chapter: Gram-negative bacteria in neonatal infections. 
  Page 121 - 138Krause JC & Weitkamp JHEditors: Pereira-da-Silva L & Neto MT.Research Signpost, Kerala, India2011
• Neonatal Neurology 
  Chapter: Infectious Diseases. 
  Page 109 - 141Weitkamp JH & Nania JJEditors: Fenichel GM.Churchill Livingstone Elsevier, Philadelphia, PA2007
• Fetal and Neonatal Physiology 
  Chapter: Chapter 155: B-Cell Development, Section XX, Developmental Immunobiology. 
  Page 1518 - 1522Crowe, Jr. JE, Weitkamp JH & Williams JVEditors: Polin /Fox/Abman.Saunders Elsevier, Philadelphia, PAEdition 3rd,2004
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Abstracts/Posters

• Congenital cutaneous candidiasis (CCC): multicenter study of presentation, diagnosis, management, and outcomes over 10 years.
  Coggins S, Weitkamp JH, Zanelli S, Kaufman DA, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Baltimore, MD, 1/1/2016
• Reducing antibiotic use through a NICU-specific antibiotic stewardship program.
  Maalouf FI, Hatch LD, Lehmann CU, Wallace T, Weitkamp, JH, Grubb PH, Vermont Oxford Network Annual Quality Congress, Chicago, IL, 1/1/2016
• Maternal inflammation induces injury and alters postnatal development of the small intestine of newborn mice.
  Elgin TG, Fricke EM, Weitkamp JH, Reese J, Gong H, McElroy SJ, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, San Diego, CA, 1/1/2015
• Fetal Inheritance of the Maternal Microbiota Prior to Birth.
  Romano-Keeler J, Zackular J, Moore DJ, Hooper C, Meng S, Brown N, Reese, JJ, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, San Diego, CA, 1/1/2015
• Liposomal Amphotericin B (AmBisome) in infants <1500g: Effectiveness and nephrotoxicity [talk in German].
  Weitkamp JH, Poets CF, Sievers R, Musswessels E, Groneck P, Thomas P, Bartmann P, 1/1/2014
• IUGR alters mouse intestinal architecture during development.
  White JR, McElroy S, Brown AS, Gong H, Weitkamp JH, Fung CM, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2014
• Neonatal peritonitis alters murine small intestinal architecture during development.
  Ekhaguere OA, Wynn J, Pope B, Martin K, Weitkamp JH, McElroy SJ, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2014
• Smad7 Drives Intestinal Immune Dysregulation after Chorioamnionitis.
  Coggins S, Moore DJ, Olivares-Villagomez D, Wynn J, Romano-Keeler J, Matta P, Brown, N, Marshall, A, Maheshwari A, Reese J, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2014
• Intestinal tissue versus fecal microbiome as a risk factor for necrotizing enterocolitis.
  Romano-Keeler J, Moore DJ, Brucker R, Lovvorn H, Wang C, Tang YW, Bordenstein S, George AL, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Washington, DC, 1/1/2013
• Effect of neutropenia on serial C-reactive protein levels in bacteremic neonates.
  Coggins S, Wynn J, Hill ML, Slaughter C, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Washington, DC, 1/1/2013
• The incidence of catheter related bloodstream infections in neonates following removal of peripherally inserted central venous catheter.
  Casner M, Hoesli S, Slaughter C, Hill M, Weitkamp JH, Annual Meeting of the Academic Pediatric Association – Pediatric Hospital Medicine, Covington, KY, 1/1/2012
• Novel microfluidic technology can identify changes in leukocyte physiology following severe trauma.
  Brady JS, Seale KT, Weitkamp JH, Wikswo JP, May AK, Norris PR, 7th International Federation of Shock Societies and the 35th Annual Conference on Shock, Miami, FL, 1/1/2012
• Hyperoxia causes and minocycline prevents damage to oligodendroglia of the immature cerebellum.
  Blanco M, Brockmoller V, Endesfelder S, Weichelt U, Bührer C, Weitkamp JH, Schmitz T, American Academy of Pediatrics (AAPAAP) National Conference and Exhibition, New Orleans, LA, 1/1/2012
• The microbiome of intestinal tissue and stool as a risk factor for necrotizing enterocolitis.
  Romano-Keeler J, Moore D, Brucker R, Fonnesbeck C, Correa H, Lovvorn H, Wang C, Bordenstein A, Tang YW, George A, Jr, Weitkamp JH, American Academy of Pediatrics National Conference & Exhibition, New Orleans, LA, 1/1/2012
• Heart rate characteristics index (HeRO score) increases in NICU patients prior to the diagnosis of necrotizing enterocolitis.
  Stone M, Attridge J, Tatum P, Weitkamp JH, Mukherjee A, Rodgers B, Lake D, Moorman R, Fairchild K, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Boston, MA, 1/1/2012
• The application of machine learning for early detection of late onset neonatal sepsis.
  Romano-Keeler J, Subramani M, Ozdas, A, Aliferis C, Varol HA, Carnevale R, Chen Y, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Boston, MA, 1/1/2012
• The incidence of catheter related bloodstream infections in neonates following removal of peripherally inserted central venous catheter.
  Casner M, Hoesli S, Slaughter C, Hill M, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Boston, MA, 1/1/2012
• Novel microfluidic technology can identify changes in leukocyte physiology following severe trauma.
  Brady S, Seale KT, Weitkamp JH, Wikswo JP, May AK, Norris PR, Shock, 1/1/2012
• Optimization of vancomycin dosing in the neonatal intensive care unit.
  Fuller P, Potts A, Gentry M, Walsh W, Weitkamp JH, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Denver, CO, 1/1/2011
• Inflammatory injury to the neonatal intestine is marked by a macrophage-rich mucosal infiltrate in contrast to pleomorphic leukocyte infiltrates in the adult.
  Krishnan MK, Kurundkar AR, Kaza N, Weitkamp JH, Maheshwari A, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Denver, CO, 1/1/2011
• Optimization of vancomycin dosing in the neonatal intensive care unit.
  Fuller P, Potts A, Gentry M, Walsh W, Weitkamp JH, 20th Annual Meeting of the Pediatric Pharmacy Advocacy Group (PPAG), Memphis, TN, 1/1/2011
• Necrotizing enterocolitis is associated with an imbalance between intestinal TCRalphaBeta CD8+ and TCRAlphaBeta CD8+ intraepithelial lymphocytes.
  Weitkamp JH, Rock M, Koyama T, Correa H, Goettel J, Matta P, Polk DB, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2010
• Pharmacokinetics and safety of meropenem in young infants with intra-abdominal infections.
  Smith PB, Capparelli EV, Castro LM, Poindexter B, Valencia G, Bidegain M, Schelonka R, Weitkamp JH, van den Anker J, Ward R, Walsh M, Burchfield D, Arrieta A, Bhatt-Me..., Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2010
• Increased apical sodium-dependent bile acid transporter in human necrotizing enterocolitis.
  Mount-Patrick S, Dobrenen H, Dvorak B, Weitkamp JH, Correa H, Halpern MD, Annual Meeting of the American Pediatric Society and Society for Pediatric Research, Vancouver, Canada, 1/1/2010
• Weitkamp JH, 17th South Central Conference on Perinatal Research, Austin, TX, 1/1/2010
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Lectures

• Resident Education in the NICU 
  1/1/2016
• Challenges of chorioamnionitis-Neonatal Infection 
  1/1/2016
• Congenital Infections 
  1/1/2016
• C-reactive Protein 
  1/1/2016
• NEC 
  1/1/2016
• Neonatal Dermatology 
  1/1/2016
• When do children inherit a microbiome? 
  Boston, MA - 1/1/2016
• Outfoxed by inflammation: maternal immune activation and necrotizing enterocolitis (NEC). 
  Children’s Hospital at Montefiore, Bronx, NY - 1/1/2015
• TORCH Update 
  Clarksville, TN - 1/1/2015
• TORCH 
  1/1/2015
• Outfoxed by inflammation: maternal influences on the neonatal gut. 
  University of Arizona, Tucson, AZ - 1/1/2015
• Effects of maternal immune activation: a role in NEC? 
  University of Wisconsin, Madison, WI - 1/1/2015
• Outfoxed by inflammation: chorioamnionitis and NEC. 
  Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA - 1/1/2014
• Outfoxed by inflammation: the effects of chorioamnionitis on the developing immune system. 
  Charite – Universitatsmedizin Berlin, Berlin, Germany - 1/1/2014
• Presentation of the Marshall Klaus Awardees. 
  San Diego, CA - 1/1/2014
• Necrotizing enterocolitis: the untold story. 
  Morristown, NJ - 1/1/2014
• Changes in mucosal immune development following chorioamnionitis. 
  Ghent University, Ghent, Belgium - 1/1/2014
• Bacterial Infections 
  Vanderbilt School of Nursing - 1/1/2014
• Microfluidics to investigate neonatal immunology. 
  Vancouver, Canada - 1/1/2014
• The role of the mucosal microbiome in NEC. 
  London, United Kingdom - 1/1/2014
• The Life Inside: How Does the Gut Microbiome Affect Neonatal Health? 
  Nashville, TN - 1/1/2013
• Development of intestinal immune regulation and necrotizing enterocolitis. 
  London, United Kingdom - 1/1/2013
• Development and regulation of the mucosal immune system in the neonate. 
  Vienna, Austria - 1/1/2013
• Chorioamnionitis and the fetal response to inflammation: effects for the developing infant. 
  Washington, DC - 1/1/2013
• TORCH Infections 
  1/1/2013
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Other

• Drug could help babies born prematurely 
  Weitkamp JH, K5 Western Washington
  Seattle, WA - 1/4/2013
• Immune system implicated in prematurity complication 
  Weitkamp JH
  www.baby-shower.kinder-host.com
  1/1/2012
• 13 ounces at birth, Becca is Tennessee's tiniest baby to survive 
  Weitkamp JH, The Tennessean
  1/13/2009
• Medical Breakthrough - Preemies Fight Infection 
  Weitkamp JH, NewsChannel 8 WQAD
  Moline, IL - 1/29/2008
• Medical Minute 10-17: Preemies Fight Infection 
  Weitkamp JH, WCTV TV
  Talahassee, Thomasville & Valdosta, FL - 1/17/2008
• Medical Breakthroughs: Infections among Premature Babies 
  Weitkamp JH, KGET TV 17
  Bakersfield, CA - 1/7/2008
• Preemies Fight Infection 
  Weitkamp JH, FOX23News
  Albany, NY - 1/1/2008
• Medical Breakthroughs: Preemies Fight Infection 
  Weitkamp JH, Ivanhoe Broadcast News
  Winter Park, FL - 1/1/2008
• While West Nile captures headlines, other viruses also deadly. 
  Weitkamp JH, WKRN-TV/DT NewsChannel 2
  Nashville, TN - 1/1/2004
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