JoelM.PalefskyMD

Infectious Disease • San Francisco, CA

Professor, Medicine, UCSF School of Medicine

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Office
1600 Divisadero St
San Francisco, CA 94143
Phone+1 415-353-7100

Fax+1 415-353-7150

Education & Training

McGill University Faculty of MedicineClass of 1980

Certifications & Licensure

CA State Medical License 1985 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Infectious Disease

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2009-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Elected Member The American Society for Clinical Investigation, 2003
Super Doctor SuperDoctors.com
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Clinical Trials

SGN-00101 in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia Start of enrollment: 2002 Dec 01
Completed
Phase 1, Phase 2
Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection Start of enrollment: 2007 Nov 01
Completed
Phase 2
Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus Start of enrollment: 2007 Sep 01
Completed
Phase 2
Vaccine Therapy in Preventing HPV in HIV-Positive Women in India Start of enrollment: 2009 Aug 01
Completed
Phase 1
Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men Start of enrollment: 2009 Jul 01
Completed
Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia Start of enrollment: 2011 Apr 01
Completed
Phase 3
Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males Start of enrollment: 2011 Jun 28
Completed
Phase 2
Gardasil Immunogenicity With Needle-Free Injection Start of enrollment: 2014 Jan 01
Completed
Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions Start of enrollment: 2015 Dec 28
Active, not recruiting
Phase 3
Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions Start of enrollment: 2014 Sep 24
Active, not recruiting
Phase 3
Incidence of HIV Infection in Screening Indian Men Who Have Sex With Men Start of enrollment: 2025 Apr 30
Not yet recruiting
Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men Start of enrollment: 2025 Apr 30
Not yet recruiting
Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico Start of enrollment: 2021 Nov 30
Recruiting
Not Applicable
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

1910 citations
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
Janice S. Chen, Enbo Ma, Lucas B. Harrington, Maria Da Costa, Xinran Tian
Science. 2018-04-27
83 citations
Variability of human papillomavirus DNA testing in a longitudinal cohort of young women.
Anna-Barbara Moscicki, Joel M. Palefsky, Gregory D. Smith, Stephen Siboshski, Gary K. Schoolnik
Obstetrics and Gynecology. 1993-10-01
87 citations
HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus.
Sharof M. Tugizov, Rossana Herrera, Peter Chin-Hong, Piri Veluppillai, Deborah Greenspan
Virology. 2013-11-01

Journal Articles

Initial Development and Content Validation of a Health-Related Symptom Index for Persons Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions
Timothy J Wilkin, Joel M Palefsky, Value in Health

Lectures

Cancer Prevention Through Human Papillomavirus Vaccination
ASCO Annual Meeting 2019 - Chicago, IL - 6/1/2019
High Resolution Anoscopy (HRA)
American Society for Colposcopy and Cervical Pathology, Providence, Rhode Island - 4/27/2012

Other

Virology of human papillomavirus infections and the link to cancer
Palefsky JM, Cranston RD
http://www.uptodate.com/contents/virology-of-human-papillomavirus-infections-and-the-link-to-cancer
UpToDate, Wolters Kluwer Health - 2012-09-28
Clinical trials of human papillomavirus vaccines
Palefsky JM, Cox JT, Castle PE
http://www.uptodate.com/contents/clinical-trials-of-human-papillomavirus-vaccines
UpToDate, Wolters Kluwer Health - 2012-12-12
Recommendations for the use of human papillomavirus vaccines
Palefsky JM, Cox JT, Castle PE
http://www.uptodate.com/contents/recommendations-for-the-use-of-human-papillomavirus-vaccines
UpToDate, Wolters Kluwer Health - 2013-02-12
Anal intraepithelial neoplasia: Diagnosis, screening, prevention, and treatment
Palefsky JM, Cranston RD
http://www.uptodate.com/contents/anal-intraepithelial-neoplasia-diagnosis-screening-prevention-and-t
UpToDate, Wolters Kluwer Health - 2013-03-18
Epidemiology of human papillomavirus infections
Palefsky JM
http://www.uptodate.com/contents/epidemiology-of-human-papillomavirus-infections
UpToDate, Wolters Kluwer Health - 2013-02-12
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Authored Content

Initial Development and Content Validation of a Health-Related Symptom Index for Persons Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial LesionsAugust 2018

Press Mentions

Winship Contributes to Anal Cancer/HSIL Outcomes Research (ANCHOR) StudyJuly 13th, 2022
Risk of Anal Cancer Significantly Lower with Treatment for Anal High-Grade Squamous Intraepithelial LesionsJune 22nd, 2022
Screening and Early Treatment Reduces Anal Cancer in People with HIVJune 17th, 2022
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Grant Support

Incidence Of HIV Among Indian Men WHO Have Sex With MenNational Cancer Institute2011
Hpv-Related Neoplasia Among Hiv-Seropositive Indian Men WHO Have Sex With MenNational Cancer Institute2011
E6 Oncoprotein Based Rapid Test For Anal NeoplasiaNational Cancer Institute2010–2011
Determinants Of Participation In An Anal Cancer Prevention TrialNational Cancer Institute2009–2010
Oral S100A9 (CALPROTECTIN) In HIV InfectionNational Institute Of Dental &Craniofacial Research2007
UCSF Predoctoral Clinical Research Training Program (RMI)National Center For Research Resources2006
Anal HPV Infection And Asil In HIV+ And HIV- WomenNational Cancer Institute2001–2006
Oral S100A8 And S100A9 (CALPROTECTIN) In HIV InfectionNational Institute Of Dental &Craniofacial Research2005
Clinical And Laboratory CoreNational Institute Of Dental &Craniofacial Research2005
UCSF Predoctoral Clinical Research Training Program(Rmi)National Center For Research Resources2005
Prevalance And Risk Factors For Anal HPV Infection And Anal Squamous IntraepiNational Center For Research Resources2005
Anal HPV Infection And Asil In HIV+ And HIV- MenNational Center For Research Resources2005
SGN-00101 In High-Grade Anal Intraepithelial Neoplasia (AIN) In HIV+ IndividualsNational Center For Research Resources2004–2005
Infrared Coagulator For Squamous Intraepithelial Neoplasia Of Anus In HIV+National Center For Research Resources2004–2005
Anal HPV &Asil In HIV+ &Hiv- WomenNational Center For Research Resources2004–2005
HPV And Mrps In Oral Cancer PathogenesisNational Institute Of Dental &Craniofacial Research2001–2005
Natural HX Of Papilloma-Associated Mucosal Lesions, Normal And ImmunosuppressedNational Center For Research Resources2004
EBV And Responding Host Genes In HIV InfectionNational Institute Of Dental &Craniofacial Research2000–2004
Phase I/II Stage OPEN Label Noncomparative Study Of DFMO In HIV Infected MenNational Center For Research Resources1998–2002
Natural History Of Anal Neoplasia--Actg 216National Center For Research Resources1996–2002
Natural History Of Anal Neoplasia In HIV Infected MenNational Cancer Institute1994–2002
Epithelial/Stromal Interactions In Oral CancerNational Institute Of Dental &Craniofacial Research1996–2001
Molecular Pathogenesis 0f Hairy LeukoplakiaNational Institute Of Dental &Craniofacial Research1997–1999
Oral HPV Infection In Hiv-Positive Men And WomenNational Institute Of Dental &Craniofacial Research1994–1998
Anal Neoplasia In HIV Positive And HIV Negative WomenNational Cancer Institute1995–1997
Molecular Pathogenesis Of EBV Infection In Hairy LeukoplakiaNational Institute Of Dental &Craniofacial Research1995–1996
Oral HPV Infection In HIV Positive Men And WomenNational Institute Of Dental &Craniofacial Research1995
Natural History Of Anal Neoplasia In Hiv-Infected MenNational Cancer Institute1991–1995
Natural History Of Anal Neoplasia In HIV InfectionsNational Cancer Institute1994
Anal Neoplasia Chemoprevention In HIV Positive PersonsNational Cancer Institute1993–1994