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1651 Page Mill RoadPalo Alto, CA 94306
Dr. Helms is on Doximity
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Summary
- My research program in the field of regeneration medicine is inspired by collaborations with experts in bioengineering, materials science, physics, and with colleagues in the life sciences. We focus on developing strategies to improve tissue healing through the re-activation of autologous stem cells. Adult stem cells are critical regenerative precursors that, when activated, control tissue regeneration. We are developing clinically relevant methods to drive the self-renewal and proliferation of adult stem cells in the context of wound repair.
We are especially interested in age-related changes in tissue healing; as we get older our ability to heal injuries slows down and many of these changes can be traced back to sluggish stem cells. We believe that the ability to re-activate a patient’s own stem cells presents a unique opportunity for therapeutic intervention in a broad range of conditions affecting bone, cartilage, skin, and hair.
I have a successful track record for assembling and managing multi-investigator projects and I have obtained funding from both federal and non-federal sources including the NIH and the California Institute for Regenerative Medicine (CIRM). Work on our laboratory has led to a number of patent filings, which emphasizes the translational nature of our work.
Conducting clinically relevant research is my main objective, but this goes hand-in-hand with another goal: I believe that education is one of the most important tools to improving human health. I aim to use every avenue available to transform the way people think about science and medicine, and emphasize its contribution to their daily lives. I’ve participated in TV programming (BBC, Discovery Channel, Animal Planet), taught a variety of undergraduate courses, continuing studies courses, and now a MOOC, all in an attempt in show people how science positively impacts our lives. In the end, I believe it falls to scientists to provide tangible examples- to students of all a
Education & Training
- OtherClass of 1986
Publications & Presentations
PubMed
- Corrigendum to "Hormone sensitive lipase ablation promotes bone regeneration" [Biochim. Biophys. Acta Mol. Basis Dis. Volume 1868, Issue 9, 1 September 2022, 166449].Wen-Jun Shen, Chris Still 2nd, Lina Han, Pinglin Yang, Jia Chen
Biochimica Et Biophysica Acta. Molecular Basis of Disease. 2022-11-01 - 1 citationsHormone sensitive lipase ablation promotes bone regeneration.Wen-Jun Shen, Chris Still Ii, Lina Han, Pinglin Yang, Jia Chen
Biochimica Et Biophysica Acta. Molecular Basis of Disease. 2022-09-01 - 8 citationsDrill Hole Models to Investigate Bone Repair.Zhijun Li, Jill A. Helms
Methods in Molecular Biology. 2021-01-01
Press Mentions
- ADVENTURES ON “BRIDGES”: Humboldt State Stem Cell ResearchJanuary 19th, 2019
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