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Office
2946 E Banner Gateway Dr
Gilbert, AZ 85234Phone+1 480-256-6444Fax+1 623-207-3358
Summary
- I graduated from China Medical University. After that, I pursued Ph.D. in molecular pharmacology at University of Illinois in Chicago, Illinois. I completed internal medicine internship and residency training at Cook County hospital in Chicago, Illinois and subsequently received fellowship training in hematology and oncology at Baylor College of Medicine in Houston, Texas.
I am triple board-certified in internal medicine, hematology and medical oncology. I joined Banner MD Anderson Cancer Center in 2016 and has been focusing on clinical practice and research in lung, head & neck cancers.
I have over 20 years of experience in both basic and clinical research. My passion has been early drug development. I am the principal investigator or co-principal investigator of many ongoing clinical trials at BMDACC. Most recently, I participated in Regeneron study as a site-PI, which was published in New England Journal of Medicine in 2018. The study drug, now known as Cemiplimab, was approved by FDA to treat advanced cutaneous squamous cell carcinoma.
Selected ongoing Clinical trials (25 total)
1. An Phase 1/2 Study of RP1 as a Single Agent and in Combination with PD1 Blockade in Patients with Solid Tumors
2. A Phase 1 Study of RGX-104 With or Without Nivolumab in Patients with Advanced Solid Malignancies
3. A Phase 1b Dose-Escalation Study of Cabozantinib Administered Alone or in Combination with Atezolizumab to Subjects with Locally Advanced or Metastatic Solid Tumors
4. A Phase I/II study of HB-201 as monotherapy or in combination with nivolumab in patients with human Papillomavirus 16 positive (HPV 16+) confirmed cancers
5. A Phase 1 Study Evaluating the Safety and Efficacy of HPV16 E7 T Cell Receptor Engineered T Cells (KITE-439) in HLA-A*02:01+ Subjects with
Relapsed/Refractory HPV16+ Cancers
6. A Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T
Education & Training
- Baylor College of MedicineFellowship, Hematology and Medical Oncology, 2007 - 2010
- Cook County Health and Hospitals SystemResidency, Internal Medicine, 2004 - 2007
- China Medical University ShenyangClass of 1995
Certifications & Licensure
- AZ State Medical License 2011 - 2026
- IL State Medical License 2004 - 2011
- TX State Medical License 2009 - 2011
Awards, Honors, & Recognition
- Top Doctors:Arizona State Castle Connolly, 2013
Clinical Trials
- Capecitabine With Digoxin for Metastatic Breast Cancer Start of enrollment: 2013 Apr 01
- (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and Peritoneal Carcinoma Start of enrollment: 2013 Sep 01
- Hepatic Artery Infusion With FOLFOX in Liver Metastasis From Breast Cancer Start of enrollment: 2012 Dec 01
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Publications & Presentations
PubMed
- 168 citationsMechanisms of resistance to BRAF and MEK inhibitors and clinical update of US Food and Drug Administration-approved targeted therapy in advanced melanoma.Sunilkumar Kakadia, Naveen Yarlagadda, Ramez Awad, Madappa N. Kundranda, Jiaxin Niu
Oncotargets and Therapy. 2018-10-17 - 141 citationsAlbumin-bound paclitaxel in solid tumors: clinical development and future directions.Madappa N. Kundranda, Jiaxin Niu
Drug Design, Development and Therapy. 2015-07-24 - 54 citationsSafety and efficacy of quavonlimab, a novel anti-CTLA-4 antibody (MK-1308), in combination with pembrolizumab in first-line advanced non-small-cell lung cancer.Ruth Perets, Jair Bar, Drew W. Rasco, Myung-Ju Ahn, Kiyotaka Yoh
Annals of Oncology. 2021-03-01
Authored Content
- - Safety and Efficacy of RP1 + Nivolumab in Patients with Non-Melanoma Skin Cancer of the Head and Neck: Results from IGNYTE Phase 1/2 Multi-Cohort Clinical TrialFebruary 2022
Press Mentions
- Overcoming Immune Blockade in Non-Small Cell Lung CancerApril 19th, 2018
- Biodesix Blood-Based Diagnostic Testing Approach to PD-L1 Detection Shows Concordance with ImmunohistochemistryNovember 1st, 2017
Professional Memberships
- Member
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