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Jessica Feldman, MD, Internal Medicine, Cambridge, MA

JessicaMorganFeldmanMDScM

Internal Medicine Cambridge, MA

Health and Culture

Resident Physician, Postdoctoral Fellow

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  • Office

    330 Mount Auburn Street
    Cambridge, MA 02138

Summary

  • Dr. Jessica Feldman is a resident physician in Cambridge, MA and is affiliated with multiple hospitals in the area, including Mount Auburn Hospital. She received her medical degree from Brown University and has been in practice 1 year. She also speaks multiple languages, including Spanish. As an MD/PhD, Dr. Feldman works at the forefront of novel technology development to both study the brain to increase our knowledge of basic neurophysiology in primary motor cortex neurons and ensembles and to identify neural correlates of cognition in M1 neurons and ensembles. She has worked on BrainGate, a pilot human clinical trial enabled by the engineering of a tiny introcortical 96+ electrode array inserted in M1 of its participants, ability to record high and low level signal data (neuronal and LFPs, and beyond). Participants who are individuals with locked-in syndrome from with a range of underlying pathology including brainstem stroke and ALS, among others. We record LFPs, higher bandwidth signal from a local neural network, and filtered collected signal to extract single spikes of multiple single neurons thru the implantable in M1 96-channel neural implant (intra-cortical arrays that can record activity of local single neurons. then extract single neurons and signals based on bandwidth filtering to reveal signal neurons and their activity. This has implications in both the applied realm and in the neurophysiological, unable to, prior to this, yield such granular information including even preferred directors of MI neurons. This work also occurs in the context of the BrainGate2 pilot human clinical trials, with multiple participants - locked in via a brain stem stroke, ALS, or upper SCI, among others.

Education & Training

  • Mount Auburn Hospital
    Mount Auburn HospitalResidency, 2023
  • Cambridge Health Alliance
    Cambridge Health AllianceInternship, Transitional Year, 2017 - 2018
  • The Warren Alpert Medical School of Brown University
    The Warren Alpert Medical School of Brown UniversityClass of 2015
  • Brown University
    Brown UniversityM.S., Neuroscience, 2015
  • The Warren Alpert Medical School of Brown University
    The Warren Alpert Medical School of Brown UniversityMD/PhD program in Neuroscience, 2010 - 2014
  • Stanford University
    Stanford UniversityBA, Human Biology, 2002 - 2006
  • Stanford University
    Stanford UniversityB.A., Human Biology, concentration in Biotechnology, Philosophy, and Ethics, with Honors, 2006

Certifications & Licensure

  • MA State Medical License
    MA State Medical License 2017 - 2018

Awards, Honors, & Recognition

  • Sigma Xi Honor Society
  • BCI Award, Finalist 2012
  • Brown Medical Research Fellow Alpert Medical School, Brown University, 2009-2010
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Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Watch, Imagine, Attempt: Motor Cortex Single-Unit Activity Reveals Context-Dependent Movement Encoding in Humans with Tetraplegia  
    Feldman J.M., Vargas-Irwin C.E., King B., Simeral JD, Sorice BL, Oakley EM, Cash SS, Eskandar EN, Friehs GM, Hochberg LR and Donoghue JP, Front Hum Neurosci, 1/1/2018

Abstracts/Posters

  • State space modeling of local field potential in motor cortex during observed, imagined and attempted arm movement in humans with tetraplegia.
    Menzer, D.L., Feldman J.M., Oakley, E., Hochberg L.R., & Donoghue J.P., Society for Neuroscience, Chicago, IL, 1/1/2014
  • Action representations with neural networks: an updated perspective on the simulation hypothesis of motor cognition.
    Feldman J.M., Truccolo W., Hochberg L.R., & Donoghue J.P., Society for Neuroscience, New Orleans, LA, 1/1/2012
  • Modulation of local field potentials in primary motor cortex during observed, imagined, and attempted arm movement in humans with tetraplegia.
    Menzer, D.L., Feldman J.M., Hochberg L.R., & Donoghue J.P., Society for Neuroscience, New Orleans, LA, 1/1/2012
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Lectures

  • Overview of the 2016 WHO Classification of CNS Tumors: a paradigm shift for neuropathology. 
    Rhode Island Hospital, Providence, RI - 1/10/2017
  • Neuroradiology two mystery cases. 
    Rhode Island Hospital, Providence, RI - 1/8/2017
  • Weight loss, cough, and leukocytosis. 
    Mount Auburn Hospital, Cambridge, MA - 1/1/2017
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Other

  • Perception, action and cognition in human motor cortex neurons: implications for neural interface system design. 
    Feldman, J.M., Master�s Thesis, Dept of Neuroscience
    Brown University, Providence, RI - 1/1/2014
  • Characterization and detection of two novel point mutations in the uroporphyriogen III synthase gene causing congenital erythropoietic porphyria. 
    Feldman, J.M., Honors Thesis, Program in Human Biology
    Stanford University - 1/1/2006

Press Mentions

  • The Gateway to Advanced Neuroprosthetics: Jessica Feldman Talks BrainGate and BCI
    The Gateway to Advanced Neuroprosthetics: Jessica Feldman Talks BrainGate and BCIMarch 4th, 2014

Research History

  • Graduate Researcher, Brown Medical Research Fellow2009 - 2014
  • Medical Student ResearcherDonoghue lab, Department of Neuroscience, Brown University2008 - 2009
  • Research AssistantStanford Center for Biomedical Ethics2005 - 2006
  • Undergraduate Researcher/American Genetics Foundation FellowDesnick lab, Department of Human Genetics, Mount Sinai School of Medicine (NY)2003 - 2006

Professional Memberships

Other Languages

  • Spanish