JerrySebagMDFACS, FRCOphth, FARVO

Ophthalmology • Huntington Beach, CA

Retinal Disease

Founding Director, VMR Institute for Vitreous Macula Retina

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Office
7677 Center Ave
Ste 400
Huntington Beach, CA 92647
Phone+1 714-901-7777

Fax+1 714-901-7770

Summary

For over 3 decades the VMR Institute for Vitreous Macula Retina in Huntington Beach has provided the highest level of expert care in a private setting while maintaining a high level of basic science and clinical research. This academic prowess has resulted in the recent (2014) publication of book entitled "Vitreous - in Health and Disease" that highlights our progress with surgery, laser therapy and pharmacotherapy of blinding diseases in the vitreous, macula, and retina. In 2019 Dr. Sebag delivered the Inaugural Robert Machemer Keynote Lecture to the European Society of Ophthalmology, outlining innovations in the diagnosis and therapy of vitreo-retinal diseases. In 2023, he delivered the Meyer-Schwickerath Lecture to the German Society of Ophthalmic Surgery (DOC), entitled "Vitreous & the Lens - a tale of two media". We are thus shaping tomorrow while expertly caring for you today.

Education & Training

Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolFellowship, Surgical Retina and Vitreous, 1984 - 1986
Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolResidency, Ophthalmology, 1980 - 1983
Cedars-Sinai Medical CenterInternship, Internal Medicine, 1979 - 1980
Columbia University Vagelos College of Physicians and SurgeonsClass of 1979
Columbia CollegeB.A., 1969 - 1973

Certifications & Licensure

CA State Medical License 1980 - 2026
FL State Medical License 1990 - 2026
NY State Medical License 1983 - 2026
MA State Medical License 1984 - 2025
American Board of Ophthalmology Ophthalmology
American College of SurgeonsFellow
American Ophthalmological SocietyMember
ARVOFellow
Royal College of Ophthalmologists, UKFellow

Awards, Honors, & Recognition

Physician of Excellence Orange County Medical Association, 2014, 2022
Southern California Super Doctor Los Angeles Magazine, 2010-2021
Keynote Lecture European Society of Ophthalmology, 2019
Senior Career Achievement Award American Academy of Ophthalmology, 2018
Fellow of ARVO Association for Research in Vision and Ophthalmology, 2010
Honorary Member La Societe Francaise d'Ophtalmologie, 2015
Fellow, ARVO Silver Award Association for Research in Vision and Ophthalmology, 2010
Career Award for Humanitarian Services to the Indigent and Uninsured LHA, O.C., 2008
Honorary Member Fondazione G. B. Bietti per lo Studio e la Ricerca in Oftalmologia, 2004
Honor Award Vitreous Society, 2002
Life Member National Registry of Who�s Who, 2000
Humanitarian of the Year Award Latino Health Access, Orange County, 1998
Honor Award American Academy of Ophthalmology, 1994
The Treacher Collins Prize Ophthalmological Society of the United Kin, 1986
Knapp Fellowship Heed Ophthalmic Foundation, 1985
B. Walsh, M.D. Award, World Meeting of Neuro-Ophthalmology 1984
1st Prix Biophysic Medical Laureat de la Societe Francaise d'Ophtalmologie, 1984
The Heed Ophthalmic Foundation Fellowship 1984
The John Simon Guggenheim Memorial Foundation Fellowship Award 1983
Bicentennial Prize Essay Contest Harvard Medical School, 1982
Edith & Denton McKane Award for Outstanding Research in Ophthalmology P & S, 1979
Titus Munson Coan Prize For Excellence In Research Columbia College of P & S, 1979
Doctor Alfred P. Steiner Research Award Columbia University, 1979
First Prize, National Essay Competition, "The Diagnosis of Health" 1979
1st Prize, National Competition on Preventive Medicine American Health Foundation, 1978
AMA-ERF/AMSA Meritorious Research Award American Federation Clinical Research, 1977
Thord-Gray Fellowship American-Scandinavian Foundation, 1973
Fellow (FACS) American College of Surgeons
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Clinical Trials

A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD Start of enrollment: 2021 Jul 01
Active, not recruiting
Phase 3
Roles: Contact

Publications & Presentations

PubMed

13 citations
Orbital Fistula: Causes and Treatment of 20 Cases
Wen Ji Wang, C. X. Li, Jerry Sebag, Chuo Ni
Archives of Ophthalmology. 1983-11-01
766 citations
The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole.
Jay S. Duker, Peter K. Kaiser, Susanne Binder, Marc D. de Smet, Alain Gaudric
Ophthalmology. 2013-12-01
310 citations
Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease
Jerry Sebag
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2004-08-10

Journal Articles

Long-term Safety & Efficacy of Limited Vitrectomy for Vision Degrading Myodesopsia
J. Sebag et al, Ophthalmology Retina, 5/15/2018
Structural and functional characteristics of lamellar macular holes
Nguyen JH, Yee KMP, Nguyen-Cuu J, Sebag J, Retina, 1/31/2018
Long-term safety and efficacy of vitrectomy for Vision Degrading Vitreopathy from vitreous floaters
Sebag J, Yee KMP, Nguyen JH, Nguyen-Cuu J, Ophthalmology Retina, 1/15/2018
The effects of aging vitreous on contrast sensitivity function
Garcia G, Khoshnevis M, Nguyen-Cuu J, Yee KMP, Nguyen JH, Sadun AA, Sebag J, Graefes Arch Clin Exp Ophthalmol, 1/1/2018
Vitreous in AMD
Sebag J, Binder S, Ophthalmology, 1/1/2018
Posterior vitreous detachment
Sebag J, Ophthalmology, 1/1/2018
Incidence of cataract surgery after vitrectomy for vitreous opacities
Yee KM, Tan HS, Lesnick-Oberstein SY, Filas B, Nguyen, J, Nguyen-Cuu J, Sebag J, Ophthalmology Retina, 1/1/2017
The effects of vitreous on proliferative diabetic retinopathy and the response to pan retinal photocoagulation
Sebag J, Nguyen-Cuu J, Graefes Arch Clin Exp Ophthalmol, 1/1/2017
Reply
Garcia GA, Khoshnevis M,�Sebag J, Am J Ophthalmol, 1/1/2017
Degradation of contrast sensitivity following posterior vitreous detachment
Garcia G, Khoshnevis M, Yee KM, Nguyen-Cuu J, Nguyen JH, Sebag J, Am J Ophthalmol, 1/1/2016
Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin
Khoshnevis M, Nguyen-Cuu J, Sebag J, AJO Case Reports, 1/1/2016
Vitreous floaters - etiology, diagnostics, and management
Milston R, Madigan M, Sebag J, Surv Ophthalmol, 1/1/2016
Vitreous: Not just through it (Guest Editorial)
Sebag J, Clin Exp Ophthalmol, 1/1/2016
Ultrasound-based quantification of vitreous floaters correlates with contrast sensitivity and quality of life
Mamou J, Wa CA, Yee KM, Silverman RH, Ketterling JA, Sadun AA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2015
Macular microcysts in mitochondrial optic neuropathies: prevalence and retinal layer thickness measurements
Carbonelli M, Savini G, Cascavilla M, Borreli E, Chican C, Salomao S, Parisi V, Sebag J, Bandello F, Sadun A, Carelli V, Barboni P, PLoS One, 1/1/2015
Proteomic analysis of the embryonic and young human vitreous
Yee KMP, Feener E, Madigan M, Jackson NJ, Gao BB, Ross Cisneros F, Provis J, Aiello LP, Sadun AA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2015
Die vitreoretinale Grenzflache und ihre Rolle in der Pathogenese vitreomakularer Erkrankungen
Sebag J, Der Ophthalmologe, 1/1/2015
Vitreous in AMD therapy � the medium is the message (Guest Editorial)
Sebag J, Retina, 1/1/2015
Vitrectomy for floaters � prospective efficacy analyses and retrospective safety profile
Sebag J, Yee, KMP, Huang L, Wa C, Sadun AA, Retina, 1/1/2014
Inner retinal optic neuropathy: vitreo-macular surgery-associated disruption of the inner retina
Pan BX, Yee MKP, Ross-Cisneros FN, Sadun AA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2014
Reassessing the surgical treatment of floaters (Feature Story)
Sebag J, Retina Today, 1/1/2014
The underlying anatomy of vitreous and its role in retinal disease
Sebag J, Retina Today, 1/1/2014
Controversies in Care - Vitrectomy for Floaters
Colucciello M, Sebag J, Koch F, Retinal Physician, 1/1/2014
Indications and considerations for chromodissection
Haritoglou C, Sebag J, Retinal Physician, 1/1/2014
Recalling the development of vitreo-retinal therapeutics from vitrectomy to pharmacologic vitreolysis
Parel JMP, Sebag J, Retina Times, 1/1/2014
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Books/Book Chapters

Ryan's Retina
Chapter: Vitreous & Vitreo-Retinal Interface
Sebag JEditors: S. Sadda.Elsevier2022
Cystoid Macular Edema
Chapter: Management of Macular Edema in Vitreo-Maculopathies
Page 91 - 120Khoshnevis M, Sebag JEditors: S. Schaal, H. Kaplan.Springer, New York, NY2016
Vitreous - in Health & Disease
Chapter: Vitreous aging and posterior vitreous detachment
Page 131 - 154Tozer K, Johnson MW, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Die vitreomakulare Traktion (VMT)
Chapter: Pathophysiologie der partiellen PVD und vitreomakularen Traktion
Page 19 - 32Sebag JEditors: M. Maier.Uni-Med, Bremen, Germany2014
Die vitreomakulare Traktion (VMT)
Chapter: Pharmakologische Vitreolyse
Page 33 - 46Sebag JEditors: M. Maier.Uni-Med, Bremen, Germany2014
Vitreous - in Health & Disease
Sebag JSpringer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreous cytokines and regression of the fetal hyaloid vasculature
Page 41 - 56Yee KMP, Feener E, Gao B, Aiello LP, Madigan MC, Provis J, Ross-Cisneros F, Sadun AA, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Diabetic vitreopathy
Page 57 - 80Gale J, Aiello LP, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreous biochemistry and artificial vitreous
Page 81 - 94Crafoord S, Ghosh F, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreo-retinal interface and inner limiting membrane
Page 165 - 192Halfter W, Sebag J, Cunningham ETEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: To see the invisible - the quest of imaging vitreous
Page 193 - 222Sebag J, Silverman RH, Coleman DJEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Anomalous PVD & Vitreoschisis
Page 241 - 265Sebag J, Niemeyer M, Koss MJEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreo-Papillary adhesion and traction
Page 299 - 310Wang MY, Sadun AA, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreous in the pathobiology of macular pucker
Page 311 - 328Tozer K, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Peripheral vitreo-retinal pathologies
Page 347 - 374Sebag J, Dunker S, Green WREditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Macular hole and macular pucker surgery with special emphasis on re-operations
Page 613 - 628Pan BX, Yee KMP, Ross-Cisneros F, Sadun AA, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Pneumatic retinopexy
Page 757 - 770Yee KMP, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Vitreous floaters and vision: Current concepts and management paradigms
Page 771 - 788Huang LC, Yee KMP, Wa CA, Nguyen JN, Sadun AA, Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreous - in Health & Disease
Chapter: Pharmacologic vitreolysis
Page 799 - 816Sebag JEditors: J. Sebag.Springer, New York, NY2014
Vitreo-Retinal Interface
Chapter: The pathophysiology of the ageing vitreous
Sebag JEditors: Girach, deSmet.Springer-Verlag, Berlin, Germany2013
Pediatric Retina
Chapter: Vitreous Biochemistry and Pharmacologic Vitreolysis
Sebag J, Tozer KEditors: Hartnett.Lippincott Williams & Wilkins, Philadelphia, PAEdition 2nd,2013
Pediatric Retina
Chapter: Vitreous and developmental vitreo-retinopathies
Tozer K, Yee KMP, Sebag JEditors: Hartnett.Lippincott Williams & Wilkins, Philadelphia, PAEdition 2nd,2013
Clinical Ophthalmology
Chapter: Vitreous Biochemistry, Structure, and Clinical Evaluation
Sebag JEditors: W Tasman, EA Jaeger.JB Lippincott Co, Philadelphia, PA2010
Essentials of Ophthalmology: Medical Retina - Focus on Retinal Imaging
Chapter: Combined SD-OCT/SLO Imaging of Vitreous & the Vitreo-Retinal Interface
Wang MY, Sebag JEditors: Holz, Spaide.Springer-Verlag2010
Encyclopedia of the Eye
Chapter: Vitreous Anatomy, Aging, and Anomalous Posterior Vitreous Detachment
Page 307 - 315Sebag JEditors: Dartt, Besharse, Dana.Elsevier, Oxford, England2010
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Abstracts/Posters

Structural and functional characteristics of lamellar macular holes
Sebag J, Jersey, Channel Islands, 1/12/2018
Vitreous � not just through it
Sebag J, Annual meeting Department of Ophthalmology, Harvard Medical School, Boston, MA, 1/9/2018
Vitreous
Sebag J, FWO Research Consortium on Nanomaterials, School of Pharmaceutical Sciences, University of Ghent, Ghent, Belgium, 1/9/2018
Nd:YAG�effects on vitreous in patients with Vision Degrading Vitreopathy
Nguyen-Cuu J, Nguyen J, Yee K M, Mamou J, Silverman R, Ketterling J,�Sebag J, Invest Ophthalmol Vis Sci, 1/1/2018
Cost-effectiveness of limited vitrectomy for Vision Degrading Vitreopathy
Rostami�B,�Nguyen-Cuu J,�Brown�G, Brown�M, Sadun AA,�Sebag J, Invest Ophthalmol Vis Sci, 1/1/2018
Vitreo-papillary adhesion in lamellar macular holes
Nguyen JH, Yee KMP, Nguyen-Cuu J,�Sebag, Invest Ophthalmol Vis Sci, 1/1/2018
Impact of multifocal intraocular lenses on contrast sensitivity function in vision degrading vitreopathy
Yee KMP, Nguyen J, Nguyen-Cuu�J,�Sebag J, Invest Ophthalmol Vis Sci, 1/1/2018
Effects of�Nd:YAG�laser on Vision Degrading Vitreopathy from vitreous�floaters
Sebag J, Annual�meeting American�Ophthalmological�Society, Dana�Point, CA, 1/1/2018
Dynamic Light Scattering of Vitreous in Patients with Vitreous Floaters Compared to Macular Pucker
Kershaw K, Nguyen D, Yee K M, Nguyen J, Harrington M, Sebag J, SPIE Optical Engineering Society, San Francisco, CA, 1/1/2017
Self-Administered Questionnaires Correlate with Visual Function and Vitreous Structure in Patients with Vitreous Floaters
Nguyen-Cuu J, Nguyen E, Yee KMP, Nguyen J, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2017
Vitreous Structure and Visual Function in Myopic Vitreopathy and Posterior Vitreous Detachment
Nguyen JH, Yee KMP, Nguyen-Cuu J, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2017
Functional and Structural Effects of Nd: YAG laser for Vitreous Floaters
Yee KMP, Mamou J, Nguyen JH, Ketterling J, Silverman RH, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2017
Dynamic Light Scattering of Vitreous in Patients with Vitreous Floaters Compared to Macular Pucker
Kershaw K, Nguyen D, Yee KM, Nguyen JH, Harrington M, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2017
Vitreous Pathology and Macular Diseases
Sebag J, Schepens Society Int�l Society, European Ophthalmology Society (SOE), Barcelona, Spain, 1/1/2017
Vitreous floaters and Vision Degrading Vitreopathy
Sebag J, 50th Annual Meeting The Retina Society, Boston, MA, 1/1/2017
Vision Degrading Vitreopathy
Sebag J, Annual Congress American College of Surgeons, San Diego, CA, 1/1/2017
Innovations in Ophthalmology
Sebag J, Grand Rounds, St. Joseph Hospital, Orange, CA, 1/9/2016
Vitrectomy for Floaters
Sebag J, Vail Vitrectomy, 1/1/2016
Quantifying Vision Beyond Visual Acuity in Macular Holes
Nguyen J, Yee K, Garcia G, Sadun AA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2016
Effects of Age and Vitreous Structure on Contrast Sensitivity
Garcia G, Yee K, Nguyen-Cuu J, Nguyen J, Mamou J, Ketterling J, Silverman R, Sadun AA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2016
Defining Clinically Significant Vitreous Floaters with Objective Quantitative Measures of Vitreous Structure and Visual Function.
Yee K, Mamou J, Ketterling J, Nguyen J, Silverman R H, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2016
Optical Sensing of Molecular Structure in Vitreous of Patients with Decreased Contrast Sensitivity
Khoshnevis M, Sampathkumar A, Garcia, GA, Sebag J, Invest Ophthalmol Vis Sci, 1/1/2016
Vitreous floaters
Sebag J, Bordeaux, France, 1/1/2016
Effects of Age, Ganglion Cell Complex, and Vitreous on Contrast Sensitivity
Sebag J, Annual Meeting of The Retina Society, San Diego, CA, 1/1/2016
Vitrectomy for Vitreous Opacities
Sebag J, AAO Retina Subspecialty Day, American Academy of Ophthalmology Annual Meeting, Chicago, IL, 1/1/2016
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