JeremyDavidWalstonMD

PubMed

• 699 citations
  Management of frailty: opportunities, challenges, and future directions.
  Elsa Dent, Finbarr C. Martin, Howard Bergman, Jean Woo, Roman Romero-Ortuno
  Lancet. 2019-10-12
• 58 citations
  Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting.
  Ran Lin, Pengcheng Zhang, Andrew G. Cheetham, Jeremy D. Walston, Peter M. Abadir
  Bioconjugate Chemistry. 2015-01-21
• 14149 citations
  Frailty in Older Adults Evidence for a Phenotype
  Linda P. Fried, Catherine M. Tangen, Jeremy D. Walston, Anne B. Newman, Calvin H. Hirsch
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 2001-03-01

Journal Articles

• Claims-Based Frailty Index Options  
  Segal, JB, Varadhan R, Carlson MC, Walston JD, J Gerontol A Biol Sci Med Sci, 1/25/2018
• Frailty, Inflammatory Markers, and Waitlist Mortality Among Patients with End-Stage Renal Disease in a Prospective Cohort Study  
  McAdams-DeMarco MA, Ying H, Thomas AG, Warsame F, Shaffer AA, Haugen CE, Garonzik-Wang JM, Desai NM, Varadhan R, Walston J, Norman SP, Segev DL, Transplantation, 1/19/2018
• Midlife Systemic Inflammation is Associated with Frailty in Later Life: The ARIC Study  
  Walker KA, Walston J, Gottesman RF, Kucharska-Newton A, Palta P, Windham BG, J Gerontol A Biol Sci Med Sci, 1/9/2018
• Topical Reformulation of Valsartan for Treatment of Chronic Diabetic Wounds  
  Abadir A, Hosseini S, Faghih M, Ansari A, Lay F, Smith B, Beselman A, Vuong D, Berger A, Tian J, Rini D, Keenahan K, Budman J, Inagami T, Fedarko N, Marti G, Harmon J..., J Invest Dermatol, 1/1/2018
• Increased Single fiber jitter level is associated with reduction in motor function with aging  
  Chung T, Tian Y, Walston J, Hoke A, Am J Phys Med Rehabil, 1/1/2018
• Frailty Screening and Interventions: Considerations for Clinical Practice  
  Walston J, Buta B, Xue QL, Clin Geriatr Med, 1/1/2018
• The complex genetics of gait speed: genome-wide meta-analysis approach  
  Ben-Avraham D, Karasik D, Verghese J, Lunetta K, Smith J, Eicher J, Vered R, Deelen J, Arnold A, Buchman A, Tanaka T, Faul J, Nethander M, Fornage M, Adams H, Matteini..., Aging, 1/10/2017
• Integrating Frailty Research into the Medical Specialties � Report from a U13 Conference  
  Walston J, Robinson T, Zieman S, Eldadah B, McFarland Horne F, Carpenter C, Althoff K, Andrew M, Blaum CS, Brown PJ, Buta B, Ely W, Ferrucci L, High KP, Kritchevsky S..., J Am Geriatr Soc, 1/1/2017
• Frailty Research Moves Beyond Risk Assessment  
  Walston J, J Gerontol A Biol Sci Med Sci, 1/1/2017
• Co-Localization of Macrophage Inhibitory Factor and Nix in Skeletal Muscle of the Aged Male Interleukin 10 Null Mouse  
  Abadir P, Ko F, Marx R, Powell L, Kieserman E, Yang H, Walston J, J Frailty Aging, 1/1/2017
• Development of a Claims-based Frailty Indicator Anchored to a Well-established Frailty Phenotype  
  Segal JB, Chang HY, Du Y, Walston JD, Carlson M, Varadhan R, Med Care, 1/1/2017
• Individual Frailty Components and Mortality In Kidney Transplant Recipients  
  McAdams-DeMarco MA, Ying H, Olorundare I, King EA, Haugen C, Buta B, Gross AL, Kalyani R, Desai NM, Dagher NN, Lonze BE, Montgomery RA, Bandeen-Roche K, Walston JD, Se..., Transplantation, 1/1/2017
• Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes  
  Abadir P, Jain A, Powell L, Xue QL, Tian J, Hamilton RG, Bennett D, Finucane T, Walston JD, Fedarko NS, Circulation, 1/30/2016
• Frailty, Length of Stay, and Mortality in Kidney Transplant Recipients: A National Registry and Prospective Cohort Study  
  McAdams-DeMarco MA, King EA, Luo X, Haugen C, DiBrito S, Shaffer A, Kucirka LM, Desai NM, Dagher NN, Lonze BE, Montgomery RA, Walston J, Segev DL, Ann Surg, 1/21/2016
• How should older adults with cancer be evaluated for frailty?  
  Huisingh-Scheetz M, Walston J, J Geriatr Oncol, 1/16/2016
• Exploring frailty and mild cognitive impairmEnt in kidney transplantation to predict biomedical, psychosocial and health cost outcomeS (GERAS): Protocol of a nationwid...  
  Mauthner O, Claes V, Walston J, Engberg S, Binet I, Dickenmann M, Golshayan D, Hadaya K, Huynh-Do U, Calciolari S, De Geest S, GERAS study consortium, For the Psychoso..., J Adv Nurs, 1/12/2016
• DNA methylation of cord blood cell types: Applications for mixed cell birth studies  
  Bakulski KM, Feinberg JI, Andrews SV, Yang J, Brown S, L McKenney S, Witter F, Walston J, Feinberg AP, Fallin MD, Epigenetics, 1/3/2016
• Role of senescence marker p16 INK4a measured in peripheral blood T-lymphocytes in predicting length of hospital stay after coronary artery bypass surgery in older adults  
  Pustavoitau A, Barodka V, Sharpless NE, Torrice C, Nyhan D, Berkowitz DE, Shah AS, Bandeen Roche KJ, Walston JD, Exp Gerontol, 1/1/2016
• Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments  
  Buta BJ, Walston JD, Godino JG, Park M, Kalyani RR, Xue QL, Bandeen-Roche K, Varadhan R, Ageing Res Rev, 1/1/2016
• Rapamycin Increases Grip Strength and Attenuates Age-Related Decline in Maximal Running Distance in Older Low Capacity Runner Rats  
  Xue Q, Yang H, Li H, Abadir P, Burks T, Koch L, Britton S, Carlson J, Chen L, Walston J, Leng S, Aging, 1/1/2016
• Renal Toxicity Associated with Salsalate in Elderly Adults with Anemia  
  Cohen HJ, Walston JD, Rao SV, Schrier SL, Artz A, Partnership for Anemia: Clinical and Translational Trials in the Elderly Consortium, J Am Geriatr Soc, 1/1/2016
• Herpesvirus Infections and Risk of Frailty and Mortality in Older Women: Women's Health and Aging Studies  
  Wang GC, Han C, Detrick B, Casolaro V, Levine DM, Fried LP, Walston JD, J Am Geriatr Soc, 1/1/2016
• Physical Frailty Assessment in Older Women: Can Simplification Be Achieved Without Loss of Syndrome Measurement Validity?  
  Xue QL, Tian J, Fried LP, Kalyani RR, Varadhan R, Walston JD, Bandeen-Roche K, Am J Epidemiol, 1/1/2016
• Physical Frailty Assessment in Older Women: Can Simplification Be Achieved Without Loss of Syndrome Measurement Validity?  
  Xue QL, Tian J, Fried LP, Kalyani RR, Varadhan R, Walston JD, Bandeen-Roche K, American Journal of Epidemiology, 1/1/2016
• Evidence for dying-back axonal degeneration in age-associated skeletal muscle decline  
  Chung T, Park JS, Kim S, Montes N, Walston J, Hoke A, Muscle Nerve, 1/1/2016
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Books/Book Chapters

• Geriatrics for Specialists 
  Chapter: Frailty 
  Page 3 - 12Walston JDSpringer, New York, NY2016
• Goldman-Cecil Medicine 
  Chapter: Common Clinical Sequelae of Aging 
  Walston JDElsevier Saunders, Philadelphia, PAEdition 25th,2016
• Evidence-Based Practice of Palliative Medicine 
  Chapter: What Are the Special Needs of Patients with Frailty? 
  Page 371 - 376Ko FC, Walston JDElsevier Saunders, Philadelphia, PA2012
• Evidence-Based Practice of Palliative Medicine 
  Chapter: What is Frailty? 
  Page 263 - 370Ko F, Walston JElsevier Saunders, Philadelphia, PA2012
• Clinics in Geriatric Medicine 
  Chapter: Frailty 
  Walston JW.B. Saunders Publishers, Philadelphia, PA2011
• Hazzard�s Geriatric Medicine and Gerontology 
  Chapter: Frailty 
  Page 631 - 645Fried LP, Walston JD, Ferrucci LMcGraw-Hill Publishers, New York, NYEdition 6th,2009
• Handbook on Immunosenescence 
  Chapter: CMV Infection and Frailty: Immunologic Consequences and Disease Pathogenesis 
  Page 1305 - 1326Wang GC, Walston JDEditors: Fulop, Hirokawa, Pawelec and Franceshi.Springer, New York, NY2009
• Diabetes in Old Age 
  Chapter: Perspectives on Diabetes Care in Old Age - A Focus on Frailty 
  Page 165 - 181Zeyfang A, Walston JDWiley-Blackwell Publishers, England, United KingdomEdition 3rd,2009
• Hazzard�s Geriatric Medicine and Gerontology 
  Chapter: Inflammation and Aging 
  Page 37 - 43Walston JDMcGraw-Hill Publishers, New York, NY2009
• Geriatric Diabetes 
  Chapter: The Genetics of Diabetes and Its Complications in Older Adults 
  Page 11 - 29Walston JD, Silver KDEditors: M.Munshi and L. Lipsitz.Taylor and Francis Publishers2007
• Handbook of Models for Human Aging 
  Chapter: Frailty as a Model of Aging 
  Page 697 - 702Walston JEditors: P. Michael Conn.Elsevier/Academic Press Publishers2006
• Longevity and Frailty 
  Chapter: Biological Markers and the Molecular Biology of Frailty 
  Page 83 - 90Walston JEditors: R. Carey, J.M. Robin, J.P. Michel, Y. Christen.Springer-Verlag, Heidelberg, Germany2005
• Geriatric Palliative Care 
  Chapter: Frailty and its Implications for Care 
  Page 93 - 109Walston JD, Fried LPEditors: R.S. Morrison and D.E. Meire.Oxford University Press, New York, NY2003
• Progress in Obesity Research 
  Chapter: Mutation detection and association studies in experimental protocols: focus on ADRBeta3 
  Page 351 - 355Walston, JDEditors: G. Medeiros-Neto, A. Halpern, and C. Bouchard.John Libbey Eurotext Ltd.2003
• Geriatric Medicine 
  Chapter: Frailty and its implications for care 
  Fried LP, Darer J, Walston JDEditors: Christine K. Cassell.Springer-Verlag, New York, NYEdition 4th,2002
• Kelly�s Textbook of Internal Medicine 
  Chapter: Approach to the Frail Elderly Patient 
  Page 3069 - 3073Fried LP, Walston JDEditors: H. David Humes.Lippincott Williams and Wilkins, Philadelphia, PAEdition 4th,2000
• Principles of Geriatric Medicine and Gerontology 
  Chapter: Frailty and Failure to Thrive 
  Page 1387 - 1402Fried L, Walston JEditors: WM Hazzard.1998
• G-Proteins and Disease 
  Chapter: The Beta-3-Adrenergic Receptor and Susceptibility to Obesity, the Insulin Resistant Syndrome and Noninsulin Dependent Diabetes Mellitus 
  Walston J, Silver K, Shuldiner AREditors: Allen M. Spiegel.Humana Press, Inc., Totowa, NJ1997
• Focus & Opinion: Internal Medicine 
  Chapter: Time of Onset of Non-insulin-dependent Diabetes Mellitus and Genetic Variation in the B3-Adrenergic-receptor Gene 
  Walston J, Silver K, Bogardus C, Knowler W, Celi F, Austin S, Manning B, Strosberg D, Stern M, Raben N, Sorkin J, Roth J, Shuldiner AEditors: Kohler P.Mosby-Year Book, Inc.1996
• The Molecular Basis of Medicine 
  Chapter: Insulin resistance and diabetes mellitus 
  Shuldiner AR, Austin SA, Walston JEditors: Dang CV and Feldman AM.Chapman and Hall, New York, NY1994
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Abstracts/Posters

• Potential. Moderators of the Race-Obesity Relationship
  Franckowiak SC, Andersen RE, Walston JD, Beamer BA, Bartlett SJ, Punjabi NM, Medicine & Science in Sports & Exercise; American College of Sports Medicine Annual Meeting, 1/1/2007
• Hematologic correlates of the geriatric syndrome of frailty
  Leng S, Koenig K, Walston J, Annual Meeting of the American Geriatric Society/American Federation for Aging Research, Chicago, IL, 1/1/2001
• Pancreatic Beta-cells expressing the Arg64 variant of the $3-adrenergic receptor exhibit abnormal insulin secretory activity
  Perfetti R, Hui H, Chamie K, Binder S, Seibert M, McLenithan J, Walston J, 36th European Association for the Study of Diabetes 26th Annual Meeting, Jerusalem, Israel, 1/1/2000
• The Polymorphic Variants of the Beta-3-Adrenergic Receptor Gene and in the TNF-a Nco Gene Do not Influence Traits Related to Type 2 Diabetes and Obesity
  Johnson S, Seibert M, Thorne N, Andersen R, Walston J, Annual Meeting of the American Geriatric Society/American Federation for Aging Research, Philadelphia, PA, 1/1/1999
• Acute Insulin Response to Glucose is Lower in Individuals Homozygous for the Arg 64 Variant of the Beta-3-Adrenergic Receptor
  Walston J, Silver K, Hilfiker H, Andersen R, Roth J, Poehlman E, Shuldiner A, American Diabetes Association 59th Scientific Session, San Diego, CA, 1/1/1999
• Genomic Characterization and Identification of Promoter Elements in the Human Myostatin Gene
  Walston J, Seibert M, Fourth European Congress of Gerontology, Berlin, Germany, 1/1/1999
• Myostatin Genomic organization and polymorphic variation in an aging cohort
  Seibert M, Xue Q, Walston J, The Gerontological Society of America 52nd Annual Scientific Meetings, San Francisco, CA, 1/1/1999
• Glucose Effectiveness and Acute Insulin Response are Impaired in Individuals Homozygous for the Arg64 Variant of the Beta 3 Adrenergic Receptor
  Walston J, Silver K, Martis H, Anderson R, Roth J, Shuldiner A, VII International Symposium on Insulin Receptors and Insulin Action Molecular and Clinical Aspects, Jerusalem, Israel, 1/1/1998
• Physiologic Correlates of Frailty in the Cardiovascular Health Study Cohort
  Walston J, 51st Annual Scientific Meeting of the Gerontological Society of America, Philadelphia, PA, 1/1/1998
• The TRP64ARG Beta-3-Adrenergic Receptor Variant is Not Associated with the Insulin resistant Syndrome in the Baltimore Longitudinal Study on Aging Population
  Walston J, Sorkin J, Muller D, Silver K, Laheri A, Valdes F, Tran K, Harper M, Beamer B, Elahi D, Shuldiner AR, Annual Meeting of the American Geriatric Society/American Federation for Aging Research, Atlanta, GA, 1/1/1997
• Effect of the TRP64ARG B3-Adrenoceptor Variant on Metabolism and Body Composition in Older Non-Obese Women and Men
  Starling RD, Bougopoulos CM, Walston J, Shuldiner AR, Poehlman ET, Nutrition and Energy Metabolism in the Elderly: Basic Mechanisms to Integrative Physiology, Burlington, VE, 1/1/1997
• The Beta-3-Adrenergic Receptor in the Obesity and Diabetes Prone Rhesus Monkey is Highly Homologous to the Human Receptor and Contains Arginine at Codon 64
  Walston J, Lowe A, Bodkin N, Silver K, Yang Y, Hansen B, Shuldiner AR, International Congress of Endocrinol, San Francisco, CA, 1/1/1996
• An Under representation of Male Pima Indians Homozygous for the Trp64Arg Allele of the Beta-3-Adrenergic Receptor Suggests Early Mortality
  Walston J, Silver K, Knowler WC, Bogardus C, Shuldiner AR, Gerontologic Society of Americ, Los Angeles, CA, 1/1/1995
• Identification of a Missense Mutation in the �-3-Adrenergic Receptor Gene: Potential Relevance to Obesity and NIDDM in Pima Indians
  Walston J, Silver K, Austin S, Celi FS, Raben N, Bogardus C, Knowler WC, Roth J, Shuldiner AR, 29th ADA Research symposium and the International Congress on Obesity Satellite Conference, Boston, MA, 1/1/1994
• A Missense Mutation in the Beta-3-Adrenergic Receptor Gene in Pima Indians and its Relationship to Obesity and NIDDM
  Walston J, Silver K, Austin S, Celi FS, Raben N, Bogardus C, Knowler WC, Roth J, Shuldiner AR, Genetics of NIDDM Symposium, Wuppertal, Germany, 1/1/1994
• A New Instrument to Assess Change in Functional Activity in a Frail Elderly Population
  Gloth FM, Walston J, American Geriatrics Society, Washington, DC, 1/1/1992
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Lectures

• Frailty and the CRATUS Project: Study of Allogeneic Mesenchymal Stem Cells in Aging Frailty 
  Miami, FL - 1/1/2018
• The Fire of Chronic Inflammation in Older Adults: Etiologies, Consequences, and Treatments 
  San Francisco, CA - 1/1/2017
• The Molecular and Organismal Basis of Resilience and Frailty 
  San Francisco, CA - 1/1/2017
• Frailty in Research and Clinical Settings:� Updates in Diagnosis,�Biology, and Intervention Development 
  The University of Arizona Medical Center, Tucson, AZ, 2015; Interdisciplinary Stem Cell Institute (I - 1/1/2015
• Research Integrity: The Scientist as a Responsible Member of Society 
  1/8/2014
• Connecting Age-Related Biological Decline to Frailty and Late-Life Vulnerability 
  Barcelona, Spain - 1/1/2014
• Frailty in Aging Patients: Definitions, Biology and Potential Treatments 
  Omaha, NE - 1/22/2013
• Frailty and Sarcopenia: Common Geriatric Conditions� and �Geriatric Rehabilitation 
  Beijing, China - 1/1/2013
• Frailty and Biological Vulnerability 
  The New York Academy of Sciences (NYAS), New York, NY - 1/27/2012
• How Might Senescence Impact Frailty? 
  Mayo Clinic Campus, Rochester, MN - 1/8/2012
• The Biological Basis of Frailty and Late-Life Vulnerability 
  Imperial College, London, England, United Kingdom - 1/5/2012
• The Biology of Frailty and Age-Related Vulnerability 
  Arizona Health Science Center, Tucson, AZ, 2011; Taipei, Taiwan, 2011 - 1/25/2011
• Frailty � Two Perspectives on Clinical and Scientific Challenges 
  Ottawa, Ontario, Canada - 1/22/2011
• Phenotyping Frailty: Defining Healthspan in Mouse Models 
  Groningen, The Netherlands - 1/18/2011
• Frailty and the Biology of Late-Life Vulnerability 
  Houston, TX - 1/1/2011
• Inflammation and Frailty 
  Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA - 1/29/2010
• Frailty and the Biology of Age-Related Vulnerability 
  Mayo Clinic, Rochester, MN - 1/27/2010
• Frailty 
  UT Houston School of Medicine, Houston, TX - 1/17/2010
• The Development of Clinically Relevant Interdisciplinary Translational Research in Geriatrics: AS Johns Hopkins Experience 
  UT Houston School of Medicine, Houston, TX - 1/17/2010
• Inflammation and Micro-nutrient Metabolism 
  Orlando, FL - 1/1/2010
• Inflammation and Frailty: From Mouse to Man 
  Wake Forest, Greensboro, NC - 1/1/2009
• A workshop toward the development of the Marmoset as a model of frailty 
  San Antonio, TX - 1/1/2009
• Frailty and Late-Life Vulnerability 
  Baltimore, MD - 1/1/2008
• Genetic blueprint or environment-which has the bigger impact? 
  National Harbor, MD - 1/1/2008
• Musculoskeletal Frailty 
  Paris, France - 1/1/2008
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Other

• Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomization analysis 
  The Interleukin 1 Genetics Consortium which includes Walston J, www.thelancet.com/diabetes-endocrinology
  www.thelancet.com/diabetes-endocrinology
  1/26/2015
• Frailty: a tale of two concepts 
  Walston J, Bandeen-Roche K, BMC Medicine
  http://www.biomedcentral.com/1741-7015/13/185
  1/1/2015
• Frailty 
  Walston JD
  http://www.uptodate.com/contents/frailty
  UpToDate, Wolters Kluwer Health - 2013-03-19