JenniferSusanKoMD

PubMed

• 48 citations
  Diagnostic Distinction of Malignant Melanoma and Benign Nevi by a Gene Expression Signature and Correlation to Clinical Outcomes.
  Jennifer S. Ko, Balwir Matharoo-Ball, Steven D. Billings, Brian J. Thomson, Jean Y. Tang
  Cancer Epidemiology, Biomarkers & Prevention. 2017-07-01
• 40 citations
  Comparison between melanoma gene expression score and fluorescence in situ hybridization for the classification of melanocytic lesions
  Eugen C. Minca, Rami N. Al-Rohil, Min Wang, Paul W. Harms, Jennifer S. Ko
  Modern Pathology. 2016-08-01
• 668 citations
  Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
  Jennifer S. Ko, Arnold H. Zea, Brian I. Rini, Joanna Ireland, Paul Elson
  Clinical Cancer Research. 2009-03-15

Journal Articles

• Primary Immunoprevention of Epithelial Ovarian Carcinoma by Vaccination Against the Extracellular Domain of Anti-Müllerian Hormone Receptor II  
  Jennifer Ko, MD, Clinical Cancer Research
• Morphologic mimickers of Cryptococcus occurring within inflammatory infiltrates in the setting of neutrophilic dermatoses: a series of 3 cases highlighting clinical di...  
  Ko JS, Fernandez AP, Anderson KA, Burdick LM, Billings SD, Procop GW, McMahon JT, Bergfeld WF, Piliang MP, J Cutan Pathol, 1/1/2013
• Prostate cancer patients older than 70 years treated by radical prostatectomy have higher biochemical recurrence rate than their matched younger counterpart  
  Ko JS, Falzarano SM, Walker E, Streator-Smith K, Stephenson AJ, Klein E, Magi-Galluzzi C, Prostate, 1/1/2013
• Modification of the Tumor Microenvironment as a Novel Target of Renal Cell Carcinoma Therapeutics  
  Finke JH, Rayman PA, Ko JS, Bradley JM, Gendler SJ, Cohen PA, Cancer Journal, 1/1/2013
• Myeloid-derived suppressor cells adhere to physiologic STAT3- vs STAT5-dependent hematopoietic programming, establishing diverse tumor-mediated mechanisms of immunolog...  
  Cohen PA, Ko JS, Storkus WJ, Spencer CD, Bradley JM, Gorman JE, McCurry DB, Zorro-Manrique S, Dominguez AL, Pathangey LB, Rayman PA, Rini BI, Gendler SJ, and Finke JH, Immunol Invest, 1/1/2012
• Colonic duplication mimicking fistulizing Crohn's Colitis  
  Martin ST, Ko JS, Plesec TP, Ananthakrishnan L, Remzi FH, Inflamm Bowel Dis, 1/1/2011
• MDSC as a mechanism of tumor escape form sunitinib mediated anti-angiogenic therapy  
  Finke J, Ko J, Rini B, Rayman P, Ireland J and Cohen P, Int Immunopharmacol, 1/1/2011
• Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination  
  Bose A, Taylor JL, Alber S, Watkins SC, Garcia JA, Rini, BI, Ko JS, Cohen PA, Finke JH and Storkus WJ, Int J Cancer, 1/1/2011
• TKI and the Immune Response: Is there Potential for Combination Therapy?  
  Finke J, Ko J, Rini B, and Cohen P, Kid Cancer J, 1/1/2011
• Myeloid derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma  
  Raychaudhuri B, Rayman P, Ireland J, Ko J, Rini BI, Borden E, Garcia J, Vogelbaum MA, and Finke J, Neuro Oncol, 1/1/2011
• Direct and differential suppression of MDSC subsets by sunitinib is compartmentally constrained  
  Ko J, Rayman P, Ireland J, Swaidani S, Li G, Bunting KD, Rini B, Cohen P, Finke J, Cancer Res, 1/1/2010
• Antitumor and immune-adjuvant activities of protein-tyrosine kinase inhibitors  
  Seliger B, Massa C, Rini B, Ko J, Finke J, Trends Mol Med, 1/1/2010
• Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients  
  Ko J, Zea A, Rini B, Ireland J, Elson P, Cohen P, Golshayan A, Rayman P, Wood L, Garcia J, Driecer R, Bukowski R, Finke J, Clin Cancer Res, 1/1/2009
• Myeloid-derived suppressor cells: a novel therapeutic target  
  Ko J, Bukowski R, Finke J, Curr Oncol Rep, 1/1/2009
• Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction  
  Biswas S, Richmond A, Biswas K, Ko J, Ghosh S, Simmons M, Rayman P, Rini B, Gill I, Tannenbaum C, Finke J, J Immunol, 1/1/2009
• Renal Cell Carcinoma  
  Salas R, Ko J, Finke J, 1/1/2008
• Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice  
  Docherty JJ, Smith JS, Fu MM, Stoner T, Booth T, Antiviral Res, 1/1/2004
• Improved therapy for atopic eczema New immunomodulators clear the rash with few side effects,  
  Smith JS, Brodell RT, Postgrade Med, 1/1/2004
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Abstracts/Posters

• Histologic Pattern of Merkel Cell Carcinoma Sentinel Lymph Node Metastasis and Patient Immune Status Significantly Impacts Disease Outcome.
  Ko JS, Prieto VG, Vilain R, Scolyer R, Reynolds JP, Billings SD, United States and Canadian Academy of Pathology Annual Meeting, Boston, MA, 1/21/2015
• Differential gene expression in G-MDSC and neutrophils from renal cell carcinoma patients.
  Ko JS, Rayman P, Yang Y, Gopalan B, Finke F, Society for Immunotherapy of Cancer 29th Annual Meeting, National Harbor, MD, 1/8/2014
• Life on the edge: A series of two cases of amelanotic spindle cell melanoma with sarcomatoid dedifferentiation.
  Ko JS, Cheah A, Billings SD, The American Society of Dermatopathology 51st Annual Meeting, Chicago, IL, 1/6/2014
• Ectopic Paget's disease of the neck associated with underlying cutaneous apocrine carcinoma.
  Ko JS, Miner A, Bergfeld W, The American Society of Dermatopathology 51st Annual Meeting, Chicago, IL, 1/6/2014
• Significance of histologic pattern of Merkel cell carcinoma (MCC) metastasis in sentinel lymph node biopsies (SLNBx) and patient immune status in disease outcome.
  Ko JS, Billings SD, The American Society of Dermatopathology 51st Annual Meeting, Chicago, IL, 1/6/2014
• Bullous acrodermatitis enteropathica with atypical histopathology: an increasingly important diagnostic consideration.
  Ko JS, Kyei A, Keller E, Piliang MP, The American Society of Dermatopathology 50th Annual Meeting, Washington, DC, 1/10/2013
• Multicentric reticulohistiocytosis: case report and review of a mechanistically and therapeutically elusive disease.
  Ko JS and Fernandez AP, The American Society of Dermatopathology 50th Annual Meeting, Washington, DC, 1/10/2013
• Neutrophilic myeloid-derived suppressor cells and conventional neutrophils suppress t-cells and promote angiogenesis in malignant melanoma.
  Ko JS, Rayman P, Borden EC, Lindner D, Finke J, The American Society of Dermatopathology 50th Annual Meeting, Washington, DC, 1/10/2013
• Neutrophils from renal cell carcinoma patients show increased expression of immunosuppressive and angiogenic gene profile.
  Obery DR, Rayman PA, Yang Y, Ko JS, Finke JH, Society for Immunotherapy of Cancer 28th Annual Meeting, National Harbor, MD, 1/8/2013
• Proangiogenic Neutrophilic-Myeloid-Derived Suppressor Cells Emerge Via Two Parallel Pathways in Renal Cell Carcinoma and Melanoma.
  Ko JS, Rayman P, Borden EC, Obery D, Lindner D, Finke JH, Society for Immunotherapy of Cancer 28th Annual Meeting, National Harbor, MD, 1/8/2013
• Perineuriomatous nevus: a newly recognized variant.
  Ko JS and Billings SD, 16th Joint Meeting of the International Society of Dermatopathology, Miami, FL, 1/27/2012
• Immunohistochemical staining for p-ERK: A potential screening tool for BRAF mutations in melanoma.
  Ko JS, SD Billings, L Durkin, Lin J, W-L Wang, AJ Lazar, ED His, United States and Canadian Academy of Pathology 101st Annual Meeting, Vancouver, BC, Canada, 1/17/2012
• Fully Automated Dual ISH (DDISH) Staining for MYC Amplification: a Diagnostic Tool for Discriminating Secondary Angiosarcoma.
  Ko JS, SD Billings, AP Fernandez, CP Lanigan, RR Tubbs, United States and Canadian Academy of Pathology 101st Annual Meeting, Vancouver, BC, Canada, 1/17/2012
• Prostate cancer in patients older than 70 years treated by radical prostatectomy: clinicopathologic analysis and outcome.
  Ko JS, Falzarano SM, Walker E, Streator Smith K, Klein EA, Magi-Galluzzi C, United States and Canadian Academy of Pathology 101st Annual Meeting, Vancouver, BC, Canada, 1/17/2012
• Morphologic mimicry of Cryptococcus in the setting of neutrophilic dermatoses: a series of 3 cases highlighting a novel histologic pitfall.
  Ko JS, Fernandez AP, Anderson K, Burdick LM, Billings SD, Procop GW, McMahon JT, Bergfeld WF, and Piliang MP, The American Society of Dermatopathology 49th Annual Meeting, Chicago, IL, 1/11/2012
• Nodular Pulmonary Granuloma Formation by Acanthamoeba in a Patient Receiving Rituximab Therapy.
  Ko J, Procop G, Bhaskaran A, Desai H, McMahon J, Farver C, College of American Pathologists Annual Meeting, Grapevine, TX, 1/11/2011
• Tumor-derived Products Dynamically Convert Neutrophils into CD15+ Myeloid-Derived Suppressor Cells via Sunitinib-Sensitive and Insensitive Mechanisms.
  Ko J, Rayman P, Cohen P, Nolan B, Biswas S, Biswas K, Tannenbaum C, Lindner D, Borden E, Rini B, and Finke J, Regulatory Myeloid Cells, an International Immunopharmacology Conference, Washington, DC, 1/21/2010
• Dual Mechanistic Function of MDSC Subsets in Melanoma.
  Ko J, Rayman P, Jacobs B, Ireland J, Lindner D, Finke J, Borden E, American Society of Clinical Oncology Annual Meeting, Chicago, IL, 1/4/2010
• Sunitinib-mediated MDSC inhibition reverses tumor-induced immune suppression.
  Ko J, Rini B, Ireland J, Rayman P, Cohen P, Finke J, American Association for Cancer Research 100th Annual Meeting, Denver, CO, 1/18/2009
• Tumor-derived products dynamically activate CD15+ subset of myeloid-derived suppressor cells.
  Rayman P, Ko J, Cohen P, Finke J, Molecular Targets for Cancer Therapy: 5th Biennial Meeting, Moffitt Cancer Center, Clearwater Beach, FL, 1/12/2009
• Myeloid-specific immune cell impact of sunitinib reverses tumor-induced immune suppression.
  Ko J, Salas R, Ireland J, Rayman P, Rini B, Finke J, Cohen P, Molecular Targets for Cancer Therapy: 5th Biennial Meeting, Moffitt Cancer Center, Clearwater Beach, FL, 1/12/2009
• Glioblastoma-derived gangliosides induce T cell death by activating the caspase cascade and degradation of the anti-apoptotic RelA and Bcl2.
  Biswas K, Chahlavi A, Biswas S, Ko J, Rayman P, Das T, Sa G, Tannenbaum C, Vogelbaum M, Finke J, American Association for Cancer Research 100th Annual Meeting, Denver, CO, 1/8/2009
• Expression of Flt3 and VEGFR1 on myeloid-derived suppressor cells in renal cell carcinoma patients.
  George S, Rayman P, Biswas S, Garcia J, Ko J, Wood L, Smith-Williams T, Elson P, Driecer R, Rini B, Bukowski R, Finke J, American Society of Clinical Oncology Annual Meeting, Chicago, IL, 1/30/2008
• Immune cell changes in the peripheral blood of metastatic renal cell carcinoma patients treated with sunitinib or temsirolimus.
  Salas R, Ireland J, Ko J, Elson P, Garcia J, Wood L, Bukowski R, Rini B, Finke J, American Society of Clinical Oncology Annual Meeting, Chicago, IL, 1/30/2008
• Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in metastatic renal cell carcinoma patients.
  Ko J, Zea A, Rini B, Ireland J, Elson P, Cohen P, Golshayan A, Rayman P, Wood L, Garcia J, Driecer R, Bukowski R, Finke J, American Association for Cancer Research Annual Meeting, San Diego, CA, 1/12/2008
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Lectures

• Gross and Microscopic Symposium 
  American Academy of Dermatology - Annual Meeting 2019 - Washington, D.C. - 3/1/2019
• Cutaneous Manifestations in Inflammatory Bowel Disease: A Single Institutional Study of 209 Patients. 
  Boston, MA - 1/21/2015
• Worse outcome in melanoma patients recently pregnant: decreased T-cell programmed death receptor-1 (PD-1) expression in primary tumors suggests immune ignorance. 
  Chicago, IL - 1/8/2014
• Tumor Immunology…You've come a long way baby! 
  Cleveland Clinic, Cleveland, OH - 1/24/2013
• The Immunoscore: Coming to a Tumor Classification System Near You 
  Cleveland Clinic, Cleveland, OH - 1/19/2013
• Menkes disease: a clinical case and review. 
  Washington, DC - 1/10/2013
• What You Need to Know about Innate Immunity. 
  Cleveland, OH - 1/4/2013
• The Role of Th17 in Cancer 
  Cleveland Clinic, Cleveland, OH - 1/1/2013
• Laboratory Administration: Quality and Compliance 
  Cleveland Clinic, Cleveland, OH - 1/28/2012
• B-RAF Testing in Malignant Melanoma 
  Cleveland Clinic, Cleveland, OH - 1/23/2012
• Cutaneous Fungal Infections, from Bedside to Bench 
  Cleveland Clinic, Cleveland, OH - 1/6/2012
• Hematemesis and Dysphagia, Pathologic Correlation. 
  Cleveland Clinic Lerner College of Medicine, Cleveland, OH - 1/1/2012
• Sweet's Syndrome in the setting of AML containing a Morphologic Mimicker of Cryptococcus. 
  Seattle, WA - 1/20/2011
• Myeloid-Derived Suppressor Cells in Cancer Progression; Promotion of T-Cell Immunity by the Tyrosine Kinase Inhibitor Sunitinib. 
  Cleveland Clinic, Cleveland, OH - 1/10/2011
• Tumor-derived Products dynamically Convert Neutrophils into n-MDSC via Sunitinib-Sensitive and Insensitive Mechanisms. 
  Washington, DC - 1/24/2010
• Myeloid Derived Suppressor Cells in Cancer Progression; Promotion of T-cell Immunity by the TKI Sunitinib. 
  Cleveland Clinic, Cleveland, OH - 1/14/2010
• Myeloid-derived suppressor cells and anti-angiogenic therapy. 
  CWRU, Cleveland, OH - 1/21/2009
• Sunitinib mediated inhibition of myeloid-derived suppressor cells reverses tumor-induced immune suppression. 
  Denver, CO - 1/19/2009
• Mechanisms of Myeloid-Derived Suppressor Cell Accumulation in Cancer and Susceptibility to Reversal by Sunitinib. 
  CWRU, Cleveland, OH - 1/12/2009
• Myeloid-derived suppressor cells in renal cell carcinoma. 
  Lerner Research Institute, Department of Immunology, Cleveland, OH - 1/1/2008
• Tumor-derived gangliosides suppress T cell function. 
  CWRU, Cleveland, OH - 1/11/2007
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