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Office
3800 Reservoir Rd Nw
web: toretsky.georgetown.edu
Washington, DC 20007Phone+1 202-444-7599
Education & Training
- National Cancer InstituteFellowship, Pediatric Hematology/Oncology, 1991 - 1994
- Virginia Commonwealth University Health SystemResidency, Pediatrics, 1989 - 1991
- Duke University HospitalInternship, Pediatrics, 1988 - 1989
- University of Minnesota Medical SchoolClass of 1988
Certifications & Licensure
- DC State Medical License 2002 - 2024
- PA State Medical License 2014 - 2016
- MD State Medical License 1991 - 2011
- NC State Medical License 1988 - 1999
- American Board of Pediatrics Pediatric Hematology-Oncology
Awards, Honors, & Recognition
- Fellow National Academy of Inventors, 2018
- Elected Member The American Society for Clinical Investigation, 2007
Clinical Trials
- Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer Start of enrollment: 2017 Nov 29
- Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
- A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia Start of enrollment: 2019 Jul 03
Publications & Presentations
PubMed
- 2 citationsOpen-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma.Paul A Meyers, Noah Federman, Najat Daw, Peter M Anderson, Lara E Davis
Journal of Clinical Oncology. 2024-11-01 - Correction: YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.Tsion Zewdu Minas, Jenny Han, Tahereh Javaheri, Sung-Hyeok Hong, Michaela Schlederer
Oncotarget. 2024-02-22 - 2 citationsUSP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity.Juntae Kwon, Jinmin Zhang, Boram Mok, Samuel Allsup, Chul Kim
Molecular Cancer. 2023-12-13
Journal Articles
- Author Correction: EWS–FLI1 Increases Transcription to Cause R-loops and Block BRCA1 Repair in Ewing SarcomaKimberly Stegmaier, Stephen L Lessnick, Jeffrey A Toretsky, Nature
Press Mentions
- DC Hospital’s Comprehensive Program Extends Beyond Medical Care to Help Young Cancer PatientsMay 17th, 2022
- Adolescent and Young Adult Cancer Survivors Benefit from Area’s Only Program to Support Their Unique NeedsApril 25th, 2022
- Oncternal Therapeutics Announces Presentation of Two Abstracts at ASCO 2021 Virtual MeetingApril 28th, 2021
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Grant Support
- Novel Compounds To Inactivate Oncogenic Fusion ProteinsNational Cancer Institute2009–2012
- Isolation And Small Molecule Targeting Of Ewing'S Sarcoma Stem CellsNational Cancer Institute2008–2011
- YK-4-279 Specifically Targets ETS Family Fusion-Protein Cancers In Clinical TrialNational Cancer Institute2010
- Signaling Pathways That Determine Ewings Sarcoma OutcomeNational Cancer Institute2004–2008
- Biacore T100: ProteomicsNational Center For Research Resources2006
- Biacore T100: Prostate CancerNational Center For Research Resources2006
- Biacore T100: CancerNational Center For Research Resources2006
- Biacore T100: Breast CancerNational Center For Research Resources2006
- Biacore T100National Center For Research Resources2006
- AKT Inhibitors To Treat Ewing'S SarcomaNational Cancer Institute2004–2005
- Role Of IGF Signaling Upon Ewings Sarcoma PatientNational Cancer Institute2002–2003
- Role Of IGF Signaling Upon Ewings Sarcoma PatientNational Cancer Institute2001
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