JeffreyW.TaubMD

Pediatric Hematology & Oncology • Detroit, MI

Division Chief of Oncology, Professor of Pediatrics, Children's Hosp of Michigan, Wayne State Univer

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Office
Childrens Hospital of Michigan
3901 Beaubien BLVD Cardiology
Detroit, MI 48201
Phone+1 313-745-5835

Fax+1 313-993-0894

Education & Training

Children's Hospital of MichiganFellowship, Pediatric Hematology/Oncology, 1994
DMC Children's Hospital of Michigan1991
University of Western OntarioMD, Medicine, 1983 - 1987
University of Western OntarioClass of 1987

Certifications & Licensure

MI State Medical License 1988 - 2026
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
Super Doctor SuperDoctors.com
Fellow (FAAP) American Academy of Pediatrics

Clinical Trials

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes Start of enrollment: 2007 Mar 01
Completed
Phase 3
Low-Dose Cytarabine in Treating Infants With Down Syndrome and Transient Myeloproliferative Disorder Start of enrollment: 2006 Mar 01
Withdrawn
Phase 3
Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2008 Aug 04
Completed
Phase 3
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Start of enrollment: 2008 Jul 17
Recruiting
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Start of enrollment: 1999 Mar 15
Completed
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor Start of enrollment: 2009 Jul 13
Active, not recruiting
Phase 3
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 14
Active, not recruiting
Phase 3
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Start of enrollment: 2010 Aug 09
Completed
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma Start of enrollment: 2010 Aug 09
Active, not recruiting
Phase 3
Monitor Response to Treatment in Neuroblastoma Using 3&Apos;-Deoxy-3&Apos;-Fluorothymidine- Positron Emission Tomography (FLT-PET) Start of enrollment: 2011 Feb 01
Unknown status
Not Applicable
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 3
A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum Start of enrollment: 2012 Feb 01
Assessing Compliance With Mercaptopurine Treatment in Younger Patients With Acute Lymphoblastic Leukemia in First Remission Start of enrollment: 2012 Feb 21
Active, not recruiting
Phase 3
Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial Start of enrollment: 2012 Feb 01
Completed
Studying Biomarker Expression in Samples From Patients With Down Syndrome and Acute Myeloid Leukemia or Other Transient Myeloproliferative Disorder Start of enrollment: 2012 Feb 01
Completed
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer Start of enrollment: 2009 Sep 01
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma Start of enrollment: 2017 Mar 29
Active, not recruiting
Phase 2, Phase 3
Roles: Principal Investigator
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Publications & Presentations

PubMed

The evolution and history of Vinca alkaloids: From the Big Bang to the treatment of pediatric acute leukemia.
Jeffrey W Taub, Steven A Buck, Ana C Xavier, Holly Edwards, Larry H Matherly
Pediatric Blood & Cancer. 2024-11-01
1 citations
Panobinostat sensitizes AraC-resistant AML cells to the combination of azacitidine and venetoclax.
Jianlei Zhao, Shuangshuang Wu, Deying Wang, Holly Edwards, Jenna Thibodeau
Biochemical Pharmacology. 2024-10-01
Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML.
Shuangshuang Wu, Fangbing Liu, Yuqing Gai, Jenna Carter, Holly Edwards
Leukemia Research. 2024-09-01

Abstracts/Posters

High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction
Jeffrey W. Taub, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
The Combination of CUDC-907 and Gilteritinib Shows Promising Antileukemic Activity in Vitro and In Vivo in Preclinical Models of FLT3-ITD AML
Jeffrey W. Taub, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
The Combination of CUDC-907 and Gilteritinib Shows Promising Antileukemic Activity in Vitro and In Vivo in Preclinical Models of FLT3-ITD AML
Jeffrey W. Taub, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

Voruciclib, an Oral, Selective CDK9 Inhibitor, Enhances Cell Death Induced By the Bcl-2 Selective Inhibitor Venetoclax in Acute Myeloid Leukemia
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Novel Therapy for FLT3-ITD Acute Myeloid Leukemia Utilizing the Combination of CUDC-907 and Gilteritinib
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

Biomedical Engineer and Quality Assurance Expert, Jeffrey P. Taub, Joins NDA Partners as Expert ConsultantMay 27th, 2020
‘Those on the Front Lines of Cancer’ to Air on PBSOctober 3rd, 2019
A High-Throughput Screen Indicates Gemcitabine and JAK Inhibitors May Be Useful for Treating Pediatric AMLMay 16th, 2019
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Grant Support

Molecular And Pharmacologic Correletes Of Acute Myeloid Leukemia In DOWN SyndromeNational Cancer Institute2007–2011
Cystathionine B Synthase And ARA C Therapy For LeukemiaNational Cancer Institute2001–2005

Professional Memberships

American Society of Clinical Oncology - ASCO
Member
American Academy of Pediatrics - AAP
Fellow