JeffreyERubnitzMD

Pediatric Hematology & Oncology • Memphis, TN

Director, Leukemia/Lymphoma Division, St. Jude Children's Research Hospital

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Office
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105

Education & Training

Stanford Health Care-Sponsored Stanford UniversityFellowship, Pediatric Hematology/Oncology, 1991 - 1994
Stanford Health Care-Sponsored Stanford UniversityResidency, Pediatrics, 1988 - 1991
University of California San Diego School of MedicineClass of 1988

Certifications & Licensure

CA State Medical License 1989 - Present
TN State Medical License 1995 - 2026
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia Start of enrollment: 2002 Aug 01
Completed
Phase 3
Treatment of Children and Adolescents With Refractory or Relapsed Acute Myeloid Leukemia Start of enrollment: 2002 Mar 01
Completed
Phase 3
Natural Killer (NK) Cell Transplantation for AML Start of enrollment: 2005 Sep 01
Completed
Not Applicable
Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2008 Aug 04
Completed
Phase 3
Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome Start of enrollment: 2014 Aug 01
Completed
Phase 1
Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome Start of enrollment: 2016 May 03
Terminated
Phase 1
Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia Start of enrollment: 2016 Jan 14
Terminated
Phase 2
Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage Start of enrollment: 2017 Jul 11
Completed
Phase 1
PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Start of enrollment: 2019 Feb 12
Active, not recruiting
Phase 1, Phase 2
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia Start of enrollment: 2017 Jun 15
Active, not recruiting
Phase 2
Roles: Contact, Principal Investigator
Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy Start of enrollment: 2023 Feb 23
Recruiting
Phase 1
Roles: Contact, Principal Investigator
Expanded Access Program for Revumenib
Available
Roles: Contact
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Publications & Presentations

PubMed

Genomic profiling of circulating tumor DNA for childhood cancers.
Shaohua Lei, Sujuan Jia, Sunitha Takalkar, Ti-Cheng Chang, Xiaotu Ma
Leukemia. 2024-11-10
Dosing of Venetoclax in Pediatric Patients with Relapsed Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships.
Mohamed Badawi, Sathej Gopalakrishnan, Benjamin Engelhardt, Tammy Palenski, Seth E Karol
Clinical Therapeutics. 2024-10-01
Pharmacogenomic Score Effectively Personalizes Treatment of Acute Myeloid Leukemia.
Richard J Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Abdelrahman H Elsayed
Clinical Cancer Research. 2024-10-01

Abstracts/Posters

Venetoclax in Combination with High-Dose Chemotherapy Is Active and Well-Tolerated in Children with Relapsed or Refractory Acute Myeloid LeukemiaClinically Relevant Ab...
Jeffrey Rubnitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Safety and Efficacy of Venetoclax in Combination with Navitoclax in Adult and Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
Jeffrey Rubnitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
A 5-Gene Ara-C, Daunorubicin and Etoposide (ADE) Drug Response Score As a Prognostic Tool to Predict AML Treatment Outcome
Jeffrey Rubnitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Home or Away from Home: A Multi-Institution Study Comparing Medical Outcomes, Patient Perspectives, and Health-Related Quality of Life for Outpatient Versus Inpatient ...
Jeffrey Rubnitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Integrative Analysis of Pediatric Acute Leukemia Identifies Immature Subtypes That Span a T Lineage and Myeloid Continuum with Distinct Prognoses
Jeffrey Rubnitz, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures

Metabolomics Profiling Reveals Markers for Chemosensitivity and Clinical Outcomes in Pediatric AML Patients
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

Using Pharmacogenomics to Guide Induction May Reduce Racial Disparities in Pediatric AMLDecember 9th, 2023
Drug Offers Promising Approach to Improve Outcome for Children with High-Risk LeukemiaFebruary 10th, 2016
Drug Offers Promising Approach to Improve Outcome for Children with High-Risk LeukemiaFebruary 10th, 2016
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