JeffreyDavidRoizenMDPhD, FAAP

PubMed

• Letter to the editor in response to Duan X, et al, CYP4A22 loss-of-function causes a new type of vitamin D-dependent rickets (VDDR1C).
  Michael A Levine, Dong Li, Jeffrey Roizen, David Weber
  Journal of Bone and Mineral Research. 2024-12-23
• 10 citations
  A Pilot Randomized Clinical Trial of Intranasal Oxytocin to Promote Weight Loss in Individuals With Hypothalamic Obesity.
  Shana E McCormack, Zi Wang, Kristin L Wade, Anna Dedio, Nicolette Cilenti
  Journal of the Endocrine Society. 2023-03-06
• 8 citations
  Improved genetic risk scoring algorithm for type 1 diabetes prediction.
  Hui-Qi Qu, Jingchun Qu, Joseph Glessner, Yichuan Liu, Frank Mentch
  Pediatric Diabetes. 2022-05-01

Journal Articles

• Obesity Decreases Hepatic 25‐Hydroxylase Activity Causing Low Serum 25‐Hydroxyvitamin D  
  Michael A Levine, Jeffrey D Roizen, Journal of Bone and Mineral Research
• Decreased Serum 25-Hydroxyvitamin D in Aging Male Mice Is Associated with Reduced Hepatic Cyp2r1 Abundance  
  Jeffrey D Roizen, Michael A Levine, Endocrinology
• Progress in understanding type 1 diabetes through its genetic overlap with other autoimmune diseases  
  Roizen JD, Bradfield JB, Hakonarson H, Current Diabetes Reports, 1/1/2015
• A meta-analysis comparing the Biochemistry of Primary Hyperparathyroidism in Youths to the Biochemistry of Primary Hyperparathyroidism in Adults  
  Roizen, J. and Levine, MA, J Clin Endocrinol Metab, 1/1/2014
• Vitamin D and your patients: don't accept wimpy  
  Roizen, MF and Roizen JD, Anesth Analg, 1/1/2014
• Determination of reference intervals for serum total calcium in the vitamin D-replete pediatric population  
  Roizen JD, Shah V, Levine MA, Carlow DC, J Clin Endocrinol Metab, 1/1/2013
• Primary hyperparathyroidism in children and adolescents  
  Roizen J, Levine MA, Journal of the Chinese Medical Association, 1/1/2012
• Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice  
  Roizen JD, Asada M, Tong M, Tai HH, Muglia LJ, Mol Endo, 1/1/2007
• Understanding the Timing of Birth: The Continuing Challenge to Prevent Prematurity  
  Roizen JD, Muglia LJ, NeoReviews, 1/1/2006
• Modulation of Recombinant Small Conductance Ca2+-Activated K+ Channels by the Muscle Relaxant Chlorzoxazone and Structurally Related Compounds  
  Cao YJ, Dreixler JC, Roizen JD, Roberts MT, Houamed KM, Journal of Pharmacology and Experimental Therapeutics, 1/1/2001
• Patch-Clamp Analysis of Anesthetic Interactions with Recombinant, SK2 Subtype, Neuronal Calcium-Activated Potassium Channels  
  Dreixler JC, Cao YJ, Roberts MT, Roizen JD, Houamed KM, Anaesthesia and Analgesia, 1/1/2000
• Block of Recombinant Rat Brain SK Potassium Channels by Tricyclic Antidepressants and Structurally Related Compounds  
  Dreixler JC, Bian JT, Cao YJ, Roizen JD, Houamed KM, European Journal of Pharmacology, 1/1/2000
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Books/Book Chapters

• The Parathyroids 
  Chapter: Chapter 25, Primary Hyperparathyroidism in Children and Adolescents. 
  Page 389 - 399Roizen J, Levine MAElsevierEdition 3rd,2014
• 5-Minute Pediatric Consult. 
  Chapter: Growth Hormone Deficiency 
  Page 378 - 379Roizen JD, Alter CEditors: Schwartz MW.Lippincott Williams and WilkinsEdition 6th,2012
• 5-Minute Pediatric Consult. 
  Chapter: Panhypopitutarism 
  Page 620 - 621Roizen JD, Alter CEditors: Schwartz MW.Lippincott Williams and WilkinsEdition 6th,2012
• 5-Minute Pediatric Consult. 
  Chapter: Short Stature 
  Page 796 - 797Roizen JD, Bamba VEditors: Schwartz MW.Lippincott Williams and WilkinsEdition 6th,2012
• You(R) Teen: Losing Weight – The Owner’s Manual to Simple and Healthy Weight Management at Any Age. 
  Roizen MF, Rome E, Oz MC, with Ted Spiker, Craig Wynett, Zoe Oz, Linda G Kahn and Jeffrey D. RoizenFree Press, New York, NY2012
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Abstracts/Posters

• Common polymorphism in Vitamin D 25-hydroxylase gene (CYP2R1) abrogates promoter activity.
  Roizen JD, Casella A, Levine M, J Bone Miner Res; ASBMR, 1/1/2015
• Resting Energy Expenditure (REE) is Decreased in Pseudohypoparathyroidism Type 1A
  Roizen JD, Danzig J, Groleau V, Bhoj E, Mulchandani S, Casella A, Harrington J, Sochett E, Tershekovec A, Zemel B, Stallings V, Levine, M, University of Pennsylvania IDOM Annual Meeting, 1/1/2015
• Decreasing CYP2R1 activity with aging is responsible for decreased calcidiol response to calciferol supplementation with age.
  Roizen JD, Casella A, Levine M, Endocrine Reviews; ENDO Society, 1/1/2014
• Serum Total Calcium Concentrations in the Vitamin D replete Pediatric Population Clin Chem 2013.
  Roizen, JD, Levine, MA, Shah, V. and Carlow, D, Clin Chem; AACC, 1/1/2013
• Modulation of CYP2R1 Expression: A Potential Mechanism for Determining Vitamin D Requirements in Aging and Obesity.
  Roizen JD, Sasson, I, Levine M, Endocrine Reviews; ENDO Society, 1/1/2012
• Polymorphisms in the CYP2R1 Gene Present in the General Population Affect 25-hydroxylase Activity.
  Roizen, JD, Zhou, J and Levine, MA, J Bone Miner Res; ASBMR, 1/1/2012
• Nature and Nurture: Multifactoral rickets in two pre-school aged children.
  Roizen JD, Levine M, E-PAS; PAS, 1/1/2011
• 15-Hydroxyprostaglandin Dehydrogenase in Mouse Pregnancy.
  Roizen, JD, Asada M, Vogt S, Tong M, Tai HH, Muglia LJ, ENDO Society, 1/1/2005
• A molecular mechanism of action for neuroprotectants and paralytic drugs.
  Cao YJ, Dreixler J. C., Roizen JD., Roberts M.T., Houamed K. M., Anesthesiology, 1/1/2000
• Are SK channels the molecular target for action of antidepressants, anticonvulsants, and antipsychotics on neurons?
  Dreixler J. C., Bian JT, Cao YJ, Roizen JD., Houamed K. M., Anesthesiology, 1/1/2000
• Riluzole: Chlorzoxazone and analogs activate recombinant small conductance calcium activated potassium channels in a calcium independent manner.
  Dreixler J. C., Cao YJ, Roizen JD., Roberts M.T., Richardson J.L., Houamed K. M., Neuroscience Abs, 1/1/2000
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Lectures

• Vitamin D in Children and Hyper and Hypocalcemia in Children 
  Lancaster, PA - 1/8/2015
• Hypoparathyroidism, Pseudohypoparathyroidism and APS1 
  Sacramento, CA - 1/6/2014
• Exenetide (Byetta) Prevents Obesity in Mouse Model of Hypothalamic Obesity. 
  1/1/2014
• The Electronic Lab notebook: A case report. 
  Philadelphia, PA - 1/1/2012
• 15-Hydroxyprostaglandin Dehydrogenase in Mouse Pregnancy. 
  1/1/2006
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Other

• Metformin alters cardiometabolic fitness and may alter propensity to exercise. 
  Roizen JD, Pediatrics Online
  http://pediatrics.aappublications.org/content/131/3/e850.full/reply#pediatrics_el_55451
  1/25/2013
• Letter in Response to The Numbers Behind the Transit Strike 
  Roizen JD, The Wall Street Journal Online
  http://www.wsj.com/articles/SB113631113499836645
  New York, NY - 1/6/2006