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Office
4429 Faraday Pl NW
Washington, DC 20016
Summary
- Dr. Jeffrey Moscow graduated from Harvard University in 1973 and the Geisel School of Medicine at Dartmouth in 1982, and completed his training with a pediatrics internship and residency at the University of Texas Southwestern Medical Center and a fellowship in pediatric oncology at the National Cancer Institute (NCI) in the National Institutes of Health (NIH) Clinical Center. After fellowship, he continued basic and clinical research at NCI and joined the US Public Health Service. In 1997, he moved from NCI to the University of Kentucky, where he was Children’s Miracle Network Professor of Pediatrics, Chief of Pediatric Hematology-Oncology, Vice Chair of Pediatrics, and co-leader of the Experimental Therapeutics Program of the Markey Cancer Center. He returned to NCI in 2014 as a medical officer in the Investigational Drug Branch (IDB) of the Cancer Therapy Evaluation Program. He became branch chief of IDB in January, 2018 and retired in August, 2023. At NCI, Dr. Moscow also served as the initial program director of PDXNet, a grant program designed to incorporate pre-clinical evidence developed with patient-derived models into NCI’s clinical drug development efforts; and as the NCI co-lead of the ComboMATCH Precision Medicine Initiative, a clinical trial platform testing promising targeted drug combinations in multiple clinical trials. His scholarly work has included basic research into mechanisms of cancer drug resistance, and reports of early phase cancer clinical trials. He is an author of over 125 peer-reviewed publications, review articles and book chapters, and has been awarded 5 patents.
Education & Training
- National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1986 - 1997
- University of Texas Southwestern Medical CenterResidency, Pediatrics, 1983 - 1985
- University of Texas Southwestern Medical CenterInternship, Pediatrics, 1982 - 1983
- Geisel School of Medicine at DartmouthClass of 1982
Certifications & Licensure
- MD State Medical License 1988 - 2023
- KY State Medical License 1998 - 2017
- American Board of Pediatrics Pediatrics
Clinical Trials
- Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia Start of enrollment: 2008 Apr 01
Publications & Presentations
PubMed
- Randomized Phase II Study of Bevacizumab with Weekly Anetumab Ravtansine or Weekly Paclitaxel in Platinum-Resistant/Refractory High-Grade Ovarian Cancer (NCI Trial).Husam A Alqaisi, David E Cohn, Jing-Yi Chern, Linda R Duska, Andrea Jewell
Clinical Cancer Research. 2025-03-17 - Evaluation of Innate Immune System, Body Habitus, and Sex on the Pharmacokinetics and Pharmacodynamics of Anetumab Ravtansine in Patients With Cancer.Li Chen, Andrew T Lucas, Aaron S Mansfield, Stephanie Lheureux, Claire O'Connor
Clinical and Translational Science. 2025-03-01 - Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids.Thomas S Dexheimer, Zahra Davoudi, Nathan P Coussens, Thomas Silvers, Joel Morris
SLAS Discovery. 2025-02-23
Press Mentions
- NIH Initiative to Test New Cancer Drug CombinationsJune 3rd, 2023
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