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Office
26 Hanson Street
Unit #1
Boston, MA 02118Phone+1 617-621-8348
Education & Training
Duke University School of MedicineClass of 1977
Clinical Trials
- Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation Start of enrollment: 2006 Mar 01
- Trial of Linaclotide in Patients With Chronic Constipation Start of enrollment: 2008 Aug 01
- An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation Start of enrollment: 2008 Sep 01
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Publications & Presentations
PubMed
- 199 citationsLinaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.Joel Castro, Andrea M. Harrington, Patrick A. Hughes, Christopher M. Martin, Pei Ge
Gastroenterology. 2013-12-01 - 169 citationsLinaclotide Improves Abdominal Pain and Bowel Habits in a Phase IIb Study of Patients With Irritable Bowel Syndrome With ConstipationJeffrey M. Johnston, Caroline B. Kurtz, James E. MacDougall, Bernard J. Lavins, Mark G. Currie
Gastroenterology. 2010-12-01 - 251 citationsTwo Randomized Trials of Linaclotide for Chronic ConstipationAnthony Lembo, Harvey Schneier, S J Shiff, Caroline B. Kurtz, James E. MacDougall
The New England Journal of Medicine. 2011-08-10
Press Mentions
Ra Pharmaceuticals Strengthens Senior Management TeamMarch 1st, 2016
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