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Office
1300 Jefferson Park Ave
Charlottesville, VA 22903Phone+1 434-924-5485Fax+1 434-244-9436
Education & Training
- Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolFellowship, Surgical Retina and Vitreous, 1998 - 2001
- University of RochesterResidency, Ophthalmology, 1995 - 1998
- Zucker School of Medicine at Hofstra/NorthwellInternship, Internal Medicine, 1994 - 1995
- State University of New York Downstate Medical Center College of MedicineClass of 1994
Certifications & Licensure
- VA State Medical License 2016 - 2026
- KY State Medical License 2001 - 2025
- MA State Medical License 1999 - 2002
- NY State Medical License 1996 - 1999
- American Board of Ophthalmology Ophthalmology
Awards, Honors, & Recognition
- Fellow, National Academy of Inventors National Academy of Inventors, 2015
- NIH Director's Pioneer Award National Institutes of Health, 2014
- Chanchlani Global Vision Research Award CNIB, 2014
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Clinical Trials
- A Phase I Open Label Dose Escalation Trial of RNA-144101 in the Treatment of Geographic Atrophy Start of enrollment: 2011 Mar 01
Publications & Presentations
PubMed
- 626 citationsL1 drives IFN in senescent cells and promotes age-associated inflammationMarco De Cecco, Takahiro Ito, Anna P. Petrashen, Amy E. Elias, Nicholas J. Skvir
Nature. 2019-02-07 - 663 citationsMechanisms of age-related macular degenerationJayakrishna Ambati, Benjamin J. Fowler
Neuron. 2012-07-12 - 32 citationsRepurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes developmentJayakrishna Ambati, Joseph Magagnoli, Hannah Leung, Shaobin Wang, Chris Andrews
Nature Communications. 2020-09-23
Press Mentions
- New Way to Prevent AMD, a Common Cause of Vision LossFebruary 26th, 2023
- Link Found Between Lupus, Macular DegenerationDecember 7th, 2021
- Inhibiting Inflammation Blocks Retinal Death in Animal Models of an Untreatable BlindnessSeptember 30th, 2021
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Grant Support
- Functional Studies Of DICER1 And ALU RNA In Geographic AtrophyNational Eye Institute2012
- Endogenous Specific Inhibitor Of Corneal LymphangiogenesisNational Eye Institute2010–2012
- Intrinsic Anti-Angiogenic Activity Of SirnaNational Eye Institute2008–2011
- Pro-And Anti-Angiogenic Effects Of Vascular Endothelial Growth Factor-ANational Eye Institute2007–2011
- Novel TLR3 Inhibitors For Geographic Atrophy Of Age-Related Macular DegenerationNational Eye Institute2009–2010
- CCR3: A Molecular Marker For Neovascular AMDNational Eye Institute2009–2010
- Novel Mouse Models Of Age-Related Macular DegenerationNational Eye Institute2004–2007
Professional Memberships
- Fellow
External Links
- Laboratoryhttp://www.ambatilab.com/
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