Jay-JiguangZhuMDPHD

Neurology • Houston, TX

Neurooncology

Full Professor, Neuro-oncology of Neurosurgery Dept, University of Texas Medical School, Houston

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Office
UTHealth Neurosciences- Texas Medical Center
6400 Fannin St. Ste 2800, Dept Of Neurosurgery
Houston, TX 77030
Phone+1 713-486-8000

Fax+1 713-795-8104

Education & Training

Massachusetts General HospitalFellowship, Neuro-Oncology, 2003 - 2005
Tufts Medical CenterResidency, Neurology, 2000 - 2003
Berkshire Medical CenterInternship, Internal Medicine, 1999 - 2000
McGill University Faculty of MedicineClass of 1999

Certifications & Licensure

TX State Medical License 2010 - 2025
MA State Medical License 2005 - 2012
American Board of Psychiatry and Neurology Neurology
United Council for Neurologic SubspecialtiesNeuro-oncology

Clinical Trials

131-I-TM-601 Study in Adults With Solid Tumors Start of enrollment: 2006 Aug 01
Completed
Phase 1
A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma Start of enrollment: 2008 Aug 01
Unknown status
Phase 1, Phase 2
Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) Start of enrollment: 2009 Jun 01
Completed
Phase 3
A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastoma Start of enrollment: 2011 Dec 01
Completed
Phase 2
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant with RT & TMZ for the Treatment of Newly Diagnosed GBM Start of enrollment: 2020 Dec 08
ACTIVE_NOT_RECRUITING
NA
Roles: Contact
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) Start of enrollment: 2023 Jan 23
RECRUITING
PHASE3
Roles: Contact, Principal Investigator
A Prospective Study of a Modified Lumbar Puncture (LP) Procedure That Reduces Post-Lumbar Puncture Headaches (PLPH) in Patients Start of enrollment: 2023 Nov 08
Recruiting
Not Applicable
Roles: Principal Investigator
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Publications & Presentations

PubMed

Glioblastoma IDH-wild type: imaging independent predictors of gross total resection (GTR) using the VASARI feature set and tumoral volumetric measurements.
David Timaran-Montenegro, Luis Nunez, Antonio Dono, Octavio Arevalo, Andres Rodriguez
Acta Radiologica. 2025-03-13
Targeting tGLI1, a novel mediator of tumor therapeutic resistance, using Ketoconazole sensitizes glioblastoma to CDK4/6 therapy and chemoradiation.
Yang Yu, Austin Arrigo, Ankush Chandra, Chuling Zhuang, Mariana K Najjar
Biorxiv. 2025-02-26
3 citations
Dual inhibition of the TrkA and JAK2 pathways using entrectinib and pacritinib suppresses the growth and metastasis of HER2-positive and triple-negative breast cancers.
Angelina T Regua, Shivani Bindal, Mariana K Najjar, Chuling Zhuang, Munazza Khan
Cancer Letters. 2024-08-10

Press Mentions

Cancer-Killing Virus plus Immunotherapy Boosts Survival in Aggressive Brain CancerMay 19th, 2023
'He's My Miracle': Houston Man with Brain Tumor Given Two Months to Live, but He's Still Alive Six Years LaterJuly 18th, 2022

Professional Memberships

American Academy of Neurology - AAN
Member
American Society of Clinical Oncology - ASCO
Member
Society of Neuro-oncology
Member

Other Languages

Chinese (Mandarin)