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Office
5323 Harry Hines Boulevard
Dallas, TX 75390Phone+1 214-648-5400Fax+1 214-648-3311
Summary
- Jay Horton, MD, is a gastroenterologist based in Dallas, TX, with extensive experience in general gastroenterology, hepatology, and hepatic steatosis. He completed his medical education at the University of Iowa Roy J. and Lucille A. Carver College of Medicine and subsequent training at the University of Texas Southwestern Medical Center. Dr. Horton is recognized for his contributions to the field through multiple publications in reputable journals such as The Journal of Biological Chemistry, Cell, Cell Metabolism, Circulation, Journal of Clinical Investigation, Science, Surgical Endoscopy, and Obesity Surgery. His peers have acknowledged his professional achievements with honors such as Fellow of the American College of Physicians and election to The American Society for Clinical Investigation and Association of American Physicians.
Education & Training
- U Texas SW Med Sch1994
- University of Texas Southwestern Medical CenterResidency, Internal Medicine, 1988 - 1991
- University of Texas Southwestern Medical CenterInternship, Internal Medicine, 1988 - 1989
- University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1988
Certifications & Licensure
- TX State Medical License 1990 - 2026
Awards, Honors, & Recognition
- Association of American Physicians Association of American Physicians, 2008
- Fellow (FACP) American College of Physicians, 2011
- Elected Member The American Society for Clinical Investigation, 2003
Publications & Presentations
PubMed
- Reciprocal regulation of cardiac β-oxidation and pyruvate dehydrogenase by insulin.Abdallah Elnwasany, Heba A Ewida, Ivan Menendez-Montes, Monika Mizerska, Xiaorong Fu
The Journal of Biological Chemistry. 2024-07-01 - 14 citationsHepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.Stanislaw Deja, Justin A Fletcher, Chai-Wan Kim, Blanka Kucejova, Xiaorong Fu
Cell Metabolism. 2024-05-07 - 17 citationsDGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER.Shunxing Rong, Mingfeng Xia, Goncalo Vale, Simeng Wang, Chai-Wan Kim
Cell Metabolism. 2024-03-05
Press Mentions
- A Powerhouse of Obesity Research – Then and NowSeptember 20th, 2024
- Dallas Researchers to Lead Obesity StudySeptember 22nd, 2022
- UT Southwestern Geneticists Identify New Mechanism for Nonalcoholic Fatty Liver Disease Absent ObesitySeptember 7th, 2022
- Join now to see all
Grant Support
- TASK Force For Obesity Research At SouthwesternNational Center For Research Resources2009–2011
- Taskforce For Obesity Research At Southwestern (TORS)National Institute Of Dental &Craniofacial Research2008–2011
- TASK Force For Obesity Research At Southwestern - P20National Center For Research Resources2006–2008
- Taskforce For Obesity Research At Southwestern (TORS)National Center For Research Resources2007
- Characterization Of Microsomal Fatty Acid ElongationNational Heart, Lung, And Blood Institute2004–2007
- Pathogenesis Of Obesity And Metabolic SyndromeNational Institute Of Diabetes And Digestive And Kidney Diseases2006
- Effects Of Srebp 1C Overexpression In Fat On Liver MetabolismNational Center For Research Resources2006
- Taskforce For Obesity Research At Southwestern (RMI)National Center For Research Resources2005–2006
- Taskforce For Obesity Research At SouthwesternNational Center For Research Resources2004–2006
- Role Of Srebps In Lipoprotein Metabolism And Insulin Action In LivingNational Heart, Lung, And Blood Institute2004
- TASK Force For Obesity Research At Southwestern (RMI)National Center For Research Resources2004
- Diet, HDL, And Reverse Cholesterol TransportNational Heart, Lung, And Blood Institute2002–2003
- Srebps In Lipoprotein Metabolism And Insulin Action In Living AnimalsNational Heart, Lung, And Blood Institute2002
Professional Memberships
- Fellow
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