
Jay Fitzgerald Dorsey MD PhD
Central Nervous System Cancer
Co-Leader, Radiation Oncology Translational Center of Excellence, Abramson Cancer Center Associate Professor of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania
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Penn MedicinePhiladelphia, PA 19104
Phone+1 215-662-2428
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Summary
- As a Radiation Oncologist and tenured Associate Professor at Penn Medicine and the University of Pennsylvania, I have over 15 years of experience in treating primary and metastatic tumors of the central nervous system, using state-of-the-art techniques such as Proton therapy and Gamma Knife radiosurgery. I am board-certified in Radiation Oncology and have a PhD in Molecular Oncology from Moffitt/USF and residency training in Radiation Oncology at Penn.
I am also a translational researcher and educator in the field of cancer biology, genomics, biomarkers, and cancer nanotechnology. I have been continuously funded by the NIH for the past decade and have published in journals such as Cell and Nature. I lead a translational lab that explores novel strategies to overcome resistance and enhance sensitivity to therapies in brain tumors and other solid cancers. I am Co-Leader of the Radiation Oncology Translational Center of Excellence at Penn, member of the Institution Review Board (IRB) at the Abramson Cancer Center, and the director of the NIH-sponsored SUPERS@PENN program, which aims to foster diversity and inclusion in biomedical sciences. My mission is to advance the understanding and treatment of cancer through innovation, collaboration, and mentorship.
Education & Training
- University of Pennsylvania Health SystemResidency, Radiation Oncology, 2004 - 2008
- University of South Florida MorsaniInternship, Internal Medicine, 2003 - 2004
- University of South Florida College of MedicineClass of 2003
- University of PittsburghPrinciples and Practice, Gamma Knife Radiosurgery
Certifications & Licensure
- PA State Medical License 2004 - 2026
- NJ State Medical License 2009 - 2025
- American Board of Radiology Radiation Oncology
- University of PittsburghGamma Knife Stereotactic Radiosurgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Clinical Trials
- Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme Start of enrollment: 2009 Apr 01
Publications & Presentations
PubMed
- 1 citationsFLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy.Haiwei Ni, Zachary J Reitman, Wei Zou, Md Naushad Akhtar, Ritama Paul
Nature Cancer. 2025-03-01 - 3 citationsOccurrence, Concentration, and Distribution of 35 PFASs and Their Precursors Retained in 20 Stormwater Biofilters.Ali Beryani, Robert Furén, Heléne Österlund, Andrew Tirpak, Joseph Smith
Environmental Science & Technology. 2024-08-13 - 2 citationsA Prospective Phase I/II Clinical Trial of High-Dose Proton Therapy for Chordomas and Chondrosarcomas.Sana S Dastgheyb, Alexandra D Dreyfuss, Michael J LaRiviere, Jahan J Mohiuddin, Brian C Baumann
Advances in Radiation Oncology. 2024-05-01
Grant Support
- Summer Undergraduate Program to Educate Radiation Scientists (SUPERS)UNIVERSITY OF PENNSYLVANIA2010–2026
- Summer Undergraduate Program to Educate Radiation Scientists (SUPERS)UNIVERSITY OF PENNSYLVANIA2010–2026
- Dissecting the biology and consequence of circulating glioma cellsUNIVERSITY OF PENNSYLVANIA2020–2025
External Links
- Academic profilehttps://www.med.upenn.edu/apps/faculty/index.php/g275/p6313466
- LinkedIn profilehttps://www.linkedin.com/in/jay-dorsey-91243939
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