JawaharMehtaMDPhD

PubMed

• Reply: Is Platelet-Activating Factor the Missing Link Between COVID-19 and Atherosclerosis?
  Vignesh Chidambaram, Amudha Kumar, Jawahar L Mehta
  JACC. Advances. 2024-12-01
• Applications of ChatGPT in Heart Failure Prevention, Diagnosis, Management, and Research: A Narrative Review.
  Sai Nikhila Ghanta, Subhi J Al'Aref, Anuradha Lala-Trinidade, Girish N Nadkarni, Sarju Ganatra
  Diagnostics. 2024-10-27
• 4 citations
  Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain.
  Nirjal Mainali, Xiao Li, Xianwei Wang, Meenakshisundaram Balasubramaniam, Akshatha Ganne
  Molecular and Cellular Biochemistry. 2024-10-01

Journal Articles

• Oxidative stress and lectin-like ox-LDL-receptor LOX-1 in atherogenesis and tumorigenesis  
  Lu J, Mitra S, Wang X, Khaidakov M, Mehta JL, Antioxidants and Redox Signaling, 5/25/2011
• Prior exposure to oxidized low density lipoprotein limits apoptosis in subsequent generations of endothelial cells by altering promoter methylation  
  Mitra S, Khaidakov M, Lu J, Ayyadevara s, Szwedo J, Wang X, Chen C, Khaidakov S, Kasula S, Stone A, Mehta JL, American Journal of Physiology, 5/20/2011
• Oxidized LDL receptor 1 (OLR1) as a possible link between obesity, dyslipidemia and cancer  
  Khaidakov M, Mitra S, Kang BY, Wang X, Kadlubar S, Novelli G, Raj V, Winters M, Carter WC, Mehta JL, PLoS One, 1/1/2011
• Oxidized low-density lipoprotein and atherosclerosis Implications in anti-oxidant therapy  
  Mitra S, Deshmukh A, Sachdeva R, Lu J, Mehta JL, American Journal of Medical Sciences, 1/1/2011
• Potential involvement of LOX-1 in functional consequences of endothelial senescence  
  Khaidakov M, Wang X, Mehta JL, PLoSOne, 1/1/2011
• Death by overeating Triad of metabolic syndrome, chronic kidney disease and coronary heart disease with a focus on microalbuminuria  
  Gobal F, Deshmukh A, Shah S, Mehta JL, Journal of the American College of Cardiology, 1/1/2011
• Determining the significance of side branch lesion during bifurcation stenting (Editorial)  
  Sacheva R, Uretsky B, Mehta JL, American Journal of Cardiology, 1/1/2011
• Angiostatic effects of aspirin in hypoxia-reoxygenation are linked to modulation of TGFBeta1 signaling  
  Khaidakov M, Szwedo J, Mitra S, Mehta JL, Journal of Cardiovascular Pharmacology and Therapeutics, 1/1/2011
• Change in mortality from coronary heart disease and stroke in Arkansas 1979-2007  
  Balamurugan A, Mehta P, Bates J, Mehta JL, American Journal of Cardiology, 1/1/2011
• Calcium-dependent platelet aggregation through the interaction of phosphatidylserine and LOX-1  
  Otsui K, Kakutani M, Yuasa K, Nakano A, Hu CP, Kakino A, Sato Y, Fujita Y, Kawase Y, Jishage KI, Suzuki H, Mehta JL, Yokoyama M, Hirata KI, Inoue N, Sawamura T, Cardiovascular Research, 8/2/2010
• Anti-angiogenic and anti-mitotic effects of aspirin in hypoxia-reoxygenation Modulation of LOX-1-NADPH oxidase axis as potential mechanism  
  Khaidakov M, Szwedo J, Mitra S, Ayyadevara S, Mehta JL, Journal of Cardiovascular Pharmacology, 1/1/2010
• Systemic human Netrin-1 gene delivery by adeno-associated virus type 8 alters leukocyte accumulation and atherogenesis in vivo  
  Khan JA, Cao M, Kang BY, Liu Y, Mehta JL, Hermonat PL, Gene Ther, 1/1/2010
• Role of genomics in cardiovascular medicine  
  Novelli G, Predazzi, mango R, Romeo F, Mehta JL, World Journal of Cardiology, 1/1/2010
• Curcumin reduces angiotensin II-mediated cardiomyocyte growth via LOX-1 inhibition  
  Kang BY, Khan J, Ryu S, Shekhar R, Seung R-B, Mehta JL, Journal of Cardiovascular Pharmacology, 1/1/2010
• Aspirin resistance: Fact or fiction? A point of view  
  Mehta JL, Mohandas B, World Journal of Cardiology, 1/1/2010
• Statins and altered glucose metabolism: a laboratory curiosity or a new disease?  
  Mehta JL, Journal of the American College of Cardiology, 1/1/2010
• Circulating endothelial progenitor cells and microparticles and vascular disease (editorial)  
  Mehta JL, Szwedo J, Journal of Hypertension, 1/1/2010
• Racial disparities in prescriptions for cardioprotective drugs and cardiac outcomes in veterans affairs hospitals  
  Mehta JL, Bursac Z, Mehta P, Bansal D, Fink L, Marsh J, Sukhija R, Sachdeva R, American Journal of Cardiology, 1/1/2010
• Molecular imaging of atherosclerotic plaques targeted to oxidized LDL receptor LOX-1 using SPECT/CT and magnetic resonance  
  Li D, Patel A, Klibanov AL, Kramer CM, Ruiz M, Kang BY, Mehta JL, Beller GA, Glover DK, Meyer CH, Circulation Cardiovasc Imaging. Cardiovascular Imaging, 1/1/2010
• Genomics of cardiac remodeling in angiotensin II-treated wild-type and LOX-1-deficient mice  
  Kang BY, Hu CP, Ryu S, Khan JA, Biancolella M, Prayaga S, Seung KB, Novelli G, Mehta P, Mehta JL, Physiological Genomics, 1/1/2010
• Atrial fibrillation, catheter ablation and antiarrhythmic drug therapy  
  Paydak H, Mehta JL, Journal of the American Medical Association, 1/1/2010
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Books/Book Chapters

• Statins-Understanding Their Clinical Use 
  Editors: J.L. Mehta.Elsevier Science2003
• Inflammatory and Infectious Basis of Atherosclerosis 
  Editors: J.L. Mehta.Bioscience Birkhauser Verlag AG, Basel, Switzerland2001
• Thrombosis and Platelets in Myocardial Ischemia 
  Editors: J.L. Mehta.F.A. Davis, Philadelphia, PA1987
• Platelets and Prostaglandins in Cardiovascular Disease 
  Editors: J.L. Mehta and P. Mehta.Futura Publishing Company, Mount Kisco, NY1981
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Lectures

• Oxidative stress and atherosclerosis. 
  New Orleans, LA - 2/1/2011
• “Mechanisms of action of aspirin- a wonder drug” 
  Kyoto, Japan - 3/6/2010
• “Novel mechanisms of the effects of aspirin” 
  Tokai University, Japan - 3/3/2010
• LOX-1 in the genesis of hypertension. 
  Rome, Italy - 12/14/2009
• “Angiogenesis in Atherosclerosis; Mechanisms and Therapeutic Targets” 
  Vancouver, BC, Canada
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Other

• U.S. Patent 10/771,647 An Endothelial lined (Encased Stent, E-STENT) for Rapid Endothelialization and Preventing Restenosis. 
  
  8/10/2007
• UAMS Invention Disclosure 107-18 “Angiotensin II type 2 receptor for the treatment of cardiovascular disease” 
  Mehta JL
  12/1/2006
• US patent “60865565 Pharmaceutical Compositions for the Treatment and Prevention of Cardiovascular Conditions and Methods of Using the Same- “AT2R cDNA given with AAV” 
  Mehta JL
  11/13/2006
• WO 2005/030215 A2 “Synergistic anti-atherosclerotic effect of candersartan and rosuvastatin in apo-E knockout mice” 
  Mehta JL, World Intellectual Property Organization
  1/1/2005
• US patent 20040225346: A new endothelial coated stent for arteries. 
  Mehta JL
  11/11/2004
• US patent D6473: “Use of Statins in the Prevention and Treatment of Radiation Injury and Other Disorders Associated with Reduced Endothelial Thrombomodulin” 
  Mehta JL
  1/1/2004
• US patent: Human papillomavirus (HPV) helper functions for adeno-associated virus (AAV) replication. 
  Mehta JL
  1/1/2004
• US Patent 0322552.1 “Synergistic anti-atherosclerotic effect of candersartan and rosuvastatin in apo-E knockout mice” 
  Mehta JL
  1/1/2003
• US Patent "Detection of Myocardial Infarcts by Monocyte-Platelet Conjugates on Flow-cytometry" 
  Mehta JL
  1/1/1993
• US Patent “Reduction in Myocardial Reperfusion Injury by the Elastase Inhibitor ICI 200, 880” 
  Mehta JL
  1/1/1992
• US Patent 4790988 “Method and compositions for the treatment of thrombotic episodes” 
  Mehta JL, Washington, DC
  12/13/1988
• Thesis “Studies on experimental myocardial reperfusion" 
  Mehta JL, University of Uppsala, Uppsala, Sweden
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