JatinMaheshVyasMDPhD

PubMed

• Modeling suggests SARS-CoV-2 rebound after nirmatrelvir-ritonavir treatment is driven by target cell preservation coupled with incomplete viral clearance.
  Tin Phan, Ruy M Ribeiro, Gregory E Edelstein, Julie Boucau, Rockib Uddin
  Biorxiv. 2024-09-16
• Single-cell analysis of human airway epithelium identifies cell type-specific responses toand.
  Alfred T Harding, Arianne J Crossen, Jennifer L Reedy, Kyle J Basham, Olivia W Hepworth
  Biorxiv. 2024-09-13
• Blocking HXA-mediated neutrophil elastase release duringlung infection limits pulmonary epithelial barrier disruption and bacteremia.
  Shuying Xu, Shumin Tan, Patricia Romanos, Jennifer L Reedy, Yihan Zhang
  Mbio. 2024-09-11

Journal Articles

• Policy Recommendations for Optimizing the Infectious Diseases Physician-Scientist Workforce  
  Wendy Armstrong, Ebbing Lautenbach, Kyle J Popovich, C Buddy Creech, Roger Bedimo, Upinder Singh, Jatin M Vyas, The Journal of Infectious Diseases
• The Great Opportunity: Cultivating Scientific Inquiry in Medical Residency  
  Marc N Wein, Michael K Mansour, Jatin M Vyas, Jayaraj Rajagopal, Mark C Fishman, Kathleen E Corey, Caroline L Sokol, Katrina A Armstrong, The Journal of Infectious Diseases
• The Role of Autophagy-Related Proteins in Candida albicans Infections  
  Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM, Pathogens, 1/1/2016
• alphav Integrins combine with LC3 and atg5 to regulate Toll-like Receptor signaling in B cells  
  Acharya M, Sokolovska A, Tam JM, Conway KL, Stefani C, Raso F, Mukhopadhyay S, Feliu M, Paul E, Savill J, Hynes RO, Xavier RJ, Vyas JM, Stuart LM, and Lacy-Hulbert A, Nature Communciations, 1/1/2016
• PKCdelta activation in neutrophils promotes fungal clearance  
  Li X, Cullere X, Nishi H, Saggu G, Durand E, Mansour MK, Tam JM, Song X, Lin X, Vyas JM and Mayadas T, Journal of Leukocyte Biology, 1/1/2016
• A Critical Reappraisal of Prolonged Neutropenia as a Risk Factor for Invasive Pulmonary Aspergillosis  
  Abers MS, Ghebremichael MS, Timmons AK, Warren HS, Poznansky MC, Vyas JM, Open Forum Infectious Diseases, 1/1/2016
• Case records of the Massachusetts General Hospital Case 5-2016 — A 43-Year-Old Man with Altered Mental Status and a History of Alcohol Use  
  Terry AR, Kahle KT, Larvie M, Vyas JM, Stemmer-Rachamimov A, New England Journal of Medicine, 1/1/2016
• Human Neutrophils are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus  
  Jones CN, Dimisko L, Forrest K, Judice K, Poznansky M, Markmann JF, Vyas JM, Irimia D, Journal of Infectious Disease, 1/1/2015
• Integrated genomics of Crohn's disease risk variant identifies a role for CLEC12A in antibacterial autophagy  
  Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RH, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LAB, Vyas JM..., Cell Reports, 1/1/2015
• Role of Tet38 Efflux pump in Staphylococcus aureus Internalization and Survival in Epithelial Cells  
  Truong-Bolduc QC, Bolduc GR, Medeiros H, Vyas JM, Wang Y, Hooper DC, Infection and Immunity, 1/1/2015
• Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages  
  Kasper L, Seider K, Gerwien F, Allert S, Brunke S, Schwarzmüller T, Ames L, Barrera CZ, Mansour MK, Becken U, Barz D, Vyas JM, Reiling N, Haas A, Haynes K, Kuchler K a..., PloS One, 1/1/2014
• Macrophage-Cryptococcus Interactions: An Update  
  Mansour MK, Reedy JL, Tam JM and Vyas JM, Current Fungal Infections Report, 1/1/2014
• Modulatory role of vitamin A on the Candida albicans-induced immune response in human monocytes  
  Klassert TE, Hanisch A, Bräuer J, Klaile E, Heyl KA, Mansour MM, Tam JM, Vyas JM, Slevogt H, Medical Microbiology and Immunology, 1/1/2014
• Dectin-1-Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages  
  Tam JM, Mansour MK, Khan NS, Seward M, Puranam S, Tanne A, Sokolovska A, Becker CE, Acharya M, Baird MA, Choi AMK, Davidson MW, Segal BH, Lacy-Hulbert A, Stuart LM, Xa..., Journal of Infectious Disease, 1/1/2014
• Case records of the Massachusetts General Hospital A 76-Year-Old Man with Fever, Worsening Renal Function, and Altered Mental Status  
  Vyas JM, González RG, Pierce VM, New England Journal of Medicine, 1/1/2013
• Monocyte and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice  
  Grimm, MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan ANH, D’Auria1 A, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Röhm M, Urba..., Journal of Immunology, 1/1/2013
• Dectin-1 activation controls maturation of beta-1,3-glucan-containing phagosomes  
  Mansour MK, Tam JM, Khan NS, Seward M, Davids PJ, Puranam S, Sokolovska A, Sykes DB, Dagher Z, Becker C, Tanne A, Reedy JL, Stuart LM, and Vyas JM, Journal of Biological Chemistry, 1/1/2013
• The LRR- and RING-domain protein LRSAM1 is an E3 ubiquitin ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella typhimurium  
  Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ, Cell: Host and Microbe, 1/1/2012
• Prosthetic Joint Infections  
  Bell T. Vyas, JM, Hospital Medicine Clinics, 1/1/2012
• Fatal Fulminant Hepatic Failure from Adenovirus in Allogeneic Bone Marrow Transplant Patients  
  Vyas, JM, Marasco WA, Case Reports in Infectious Disease, 1/1/2012
• Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity  
  Tam JM, Mansour MK, Khan NS, Yoder NC, Vyas JM, Integrative Biology (Camb), 1/1/2012
• The Cell Biology of the Innate Immune Response to Aspergillus fumigatus  
  Mansour MK, Tam JM, Vyas JM, Annals of the New York Academy of Sciences, 1/1/2012
• Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging  
  Tam JM, Castro CE, Heath RJW, Mansour MK, Cardenas ML, Xavier RJ, Lang MJ, and Vyas JM, Journal of Visualized Experiments, 1/1/2011
• The Tetraspanin CD82 is Specifically Recruited to Fungal and Bacterial Phagosomes Prior to Acidification  
  Artavanis-Tsakonas K, Kasperkovitz PV, Papa E, Cardenas ML, Khan NS, Van der Veen AG, Ploegh HL, Vyas JM, Infection and Immunity, 1/1/2011
• Dragon (repulsive guidance molecule B) inhibits IL-6 expression in macrophages  
  Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY, Journal of Immunology, 1/1/2011
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Books/Book Chapters

• Clinical Infectious Disease 
  Chapter: Biologics 
  Sen P. and JM VyasEditors: D. Schlossberg.Edition 2nd,2014
• Conn’s Current Therapy 
  Chapter: Rat Bite Fever 
  JM VyasEdition 65th,2013
• Gorbach’s 5-Minute Infectious Disease Consult 
  Editors: Vyas JM (Associate Editor).Edition 2nd,2011

Lectures

• Approach to CNS infections 
  1/1/2016
• Approach to Meningitis 
  Massachusetts General Hospital - 1/1/2016
• Fun with Fungi: A Research Career Inspired by the Bigelow Medical Service. 
  Massachusetts General Hospital - 1/1/2015
• Preventing and Treating Biological Exposures 
  Eagleson Institute, Providence, RI - 1/1/2014
• Membrane Organization by Molecular Scaffolds 
  Saxtons River, VT - 1/1/2011
• Dectin-1 Controls Fungal Phagosomal Maturation 
  Newport, RI - 1/1/2011
• The Immunology of Fungal Infections 
  Galveston, TX - 1/1/2011
• The Price We Pay: Biologic Immunomodulators and Infection. 
  Massachusetts General Hospital - 1/1/2009
• Defining Immune Responses to Cryptococcus neoformans by Live Cell Imaging of Dendritic Cells 
  Cambridge, MA - 1/1/2006
• Management of Antimicrobial Resistant Pathogens in 2006. 
  Massachusetts General Hospital - 1/1/2006
• The Fate of Cryptococcus neoformans-containing Phagosomes in Primary Dendritic Cells: Insights from Live Cell Imaging 
  Boston University - 1/1/2005
• Tetraspanins and Class II MHC Molecules: Live Cell Imaging. 
  Vancouver, Canada - 1/1/2005
• Tracking the tetraspanin molecule CD63 in professional antigen presenting cells using live cell imaging 
  Children’s Hospital Boston - 1/1/2005
• From Bedside to Bench: Management of Invasive Fungal Infections and Immunity to Pathogenic Yeast. 
  Cambridge, MA - 1/1/2005
• The Fate of Cryptococcus neoformans-containing Phagosomes in Primary Dendritic Cells: Insights from Live Cell Imaging. 
  Boston University - 1/1/2005
• Modulation of Dendritic Cell Function by Cytomegalovirus. 
  New York, NY - 1/1/2004
• CD63 and Class II MHC Molecules: Live Cell Imaging. 
  Bar Harbor, ME - 1/1/2004
• Pleuropulmonary Infections: an ID perspective. 
  Massachusetts General Hospital - 1/1/2002
• Visualization of MHC class II Molecules in the Small Intestine 
  Harvard Medical School - 1/1/2002
• Visualization of MHC class II Molecules in the Small Intestine. 
  Wood’s Hole, MA - 1/1/2002
• Nantucket Fever in an HIV-infected Individual 
  Massachusetts General Hospital - 1/1/2001
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Other

• Antibiotic susceptibility testing in specific clinical situations. 
  Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH, UptoDate
  Boston, MA - 1/1/2003
• Overview of antibacterial susceptibility testing. 
  Jatin M Vyas, MD, PhD Mary Jane Ferraro, PhD, MPH, UptoDate
  Boston, MA - 1/1/2003
• The peptide binding specificity of the MHC class I-b molecule, H-2M3a. Thesis. 
  Vyas JM
  Baylor College of Medicine, Houston, TX - 1/1/1994
• Overview of antibacterial susceptibility testing 
  Vyas JM, Ferraro MJ
  http://www.uptodate.com/contents/overview-of-antibacterial-susceptibility-testing
  UpToDate, Wolters Kluwer Health - 2012-03-15
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