JasonDerekMerkerMDPhD

PubMed

• Purity Independent Subtyping of Tumors (PurIST) Pancreatic Cancer Classifier: Analytic Validation of a 16-RNA Expression Signature Distinguishing Basal and Classical S...
  Yan Li, Jason D Merker, Rachana Kshatriya, Dimitri G Trembath, Ashley B Morrison
  The Journal of Molecular Diagnostics. 2024-11-01
• Towards Preanalytical Best Practices for Liquid Biopsy Studies: A BLOODPAC Landscape Analysis.
  Christina M Lockwood, Jason D Merker, Elizabeth Bain, Caroline Compton, Robert L Grossman
  Clinical Pharmacology and Therapeutics. 2024-08-20
• 4 citations
  Clinical Testing for Tumor Cell-Free DNA: College of American Pathologists Proficiency Programs Reveal Practice Trends.
  Kelly A Devereaux, Rhona J Souers, Jason D Merker, Neal I Lindeman, Rondell P Graham
  Archives of Pathology & Laboratory Medicine. 2023-04-01

Journal Articles

• Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review  
  Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge..., Arch Pathol Lab Med, 1/1/2018
• Biallelic mutations in ATP5F1D, which encodes a subunit of ATP synthase, cause a metabolic disorder  
  Olahova M, Yoon WH, Thompson K, Jangam S, Fernandez L, Davidson JM, Kyle JE, Grove ME, Fisk DG, Kohler JN, Holmes M, Dries AM, Huang Y, Zhao C, Contrepois K, Zappala Z..., Am J Hum Genet, 1/1/2018
• ClinGen Cancer Somatic Working Group - standardizing and democratizing access to cancer molecular diagnostic data to drive translational research  
  Madhavan S, Ritter D, Micheel C, Rao S, Roy A, Sonkin D, McCoy M, Griffith M, Griffith OL, McGarvey P, Kulkarni S, on behalf of the ClinGen Somatic Working Group (Merk..., Pac Symp Biocomput, 1/1/2018
• Long-read genome sequencing identifies causal structural variation in a Mendelian disease  
  Merker JD, Wenger AM, Sneddon T, Grove M, Zappala Z, Fresard L, Waggott D, Utiramerur S, Hou Y, Smith KS, Montgomery SB, Wheeler M, Buchan JG, Lambert CC, Eng KS, Hick..., Genet Med, 1/1/2018
• Efficacy and safety of midostaurin in patients with advanced systemic mastocytosis: 10-year median follow-up of a phase II trial  
  DeAngelo DJ, George TI, Linder A, Langford C, Perkins C, Ma J, Westervelt P, Merker JD, Berube C, Coutre S, Liedtke M, Medeiros B, Sternberg D, Dutreix C, Ruffie PA, C..., Leukemia, 1/1/2018
• Circulating tumor DNA analysis in patients with cancer: American Society of Clinical Oncology and College of American Pathologists joint review  
  Merker JD, Oxnard GR, Compton C, Diehn M, Hurley P, Lazar AJ, Lindeman N, Lockwood CM, Rai AJ, Schilsky RL, Tsimberidou AM, Vasalos P, Billman BL, Oliver TK, Bruinooge..., J Clin Oncol, 1/1/2017
• Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens  
  Shoura MJ, Gabdank I, Hansen L, Merker J, Gotlib J, Levene SD, Fire AZ, G3 (Bethesda), 1/1/2017
• A novel TRIP11-FLT3 fusion in a patient with a myeloid/lymphoid neoplasm with eosinophilia  
  Chung A, Hou Y, Ohgami RS, Von Gehr A, Fisk DG, Roskin KM, Li X, Gojenola L, Bangs CD, Arber DA, Fire AZ, Cherry AM, Zehnder JL, Gotlib J, Merker JD, Cancer Genet, 1/1/2017
• A window into clinical next-generation sequencing-based oncology testing practices  
  Nagarajan R, Bartley AN, Bridge JA, Jennings LJ, Kamel-Reid S, Kim A, Lazar AJ, Lindeman NI, Moncur J, Rai AJ, Routbort MJ, Vasalos P, Merker JD, Arch Pathol Lab Med, 1/1/2017
• Somatic cancer variant curation and harmonization through consensus minimum variant level data  
  Ritter DI, Roychowdhury S, Roy A, Rao S, Landrum MJ, Sonkin D, Shekar M, Davis CF, Hart RK, Micheel C, Weaver M, Van Allen EM, Parsons DW, McLeod HL, Watson MS, Plon S..., Genome Med, 1/1/2016
• A study of the mutational landscape of pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma  
  Ozawa MG, Bhaduri A, Chisholm KM, Baker SA, Ma L, Zehnder JL, Luna-Fineman S, Link MP, Merker JD, Arber DA, Ohgami RS, Mod Pathol, 1/1/2016
• A model study of in silico proficiency testing for clinical next-generation sequencing  
  Duncavage EJ, Abel HJ, Merker JD, Bodner JB, Zhao Q, Voelkerding KV, Pfeifer JD, Arch Pathol Lab Med, 1/1/2016
• Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia  
  Alvarez-Twose I, Mart�nez-Barranco P, Gotlib J, Garc�a-Montero A, Morgado JM, Jara-Acevedo M, Merker JD, Pe�alver FJ, Matito A, Hou Y, Sanchez-Mu�oz L, Mayado A, Molle..., Leukemia, 1/1/2016
• Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutations  
  Ohgami RS, Ma L, Merker JD, Gotlib JR, Schrijver I, Zehnder JL, Arber DA, Mod Pathol, 1/1/2015
• College of American Pathologists� laboratory standards for next-generation sequencing clinical tests  
  Aziz N, Zhao Q, Bry L, Driscoll DK, Funke B, Gibson JS, Grody WW, Hedge MR, Hoeltge GA, Leonard DGB, Merker JD, Nagarajan R, Palicki LA, Robetorye RS, Schrijver I, Wec..., Arch Pathol Lab Med, 1/1/2015
• Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry  
  Chisholm KM, Merker JD, Gotlib JR, Gitana G, Lefterova M, Zehnder JL, George TI, Arber DA, Ohgami RS, Am J Clin Pathol, 1/1/2015
• Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes  
  Merker JD, Roskin KM, Ng D, Pan C, Fisk DG, King JJ, Hoh R, Stadler M, Okumoto LM, Abidi P, Hewitt R, Jones CD, Gojenola L, Clark MJ, Zhang B, Cherry AM, George TI, Sn..., Haematologica, 1/1/2013
• Feasibility of using microbeads with holographic barcodes to track DNA specimens in the clinical molecular laboratory  
  Merker JD, O�Grady N, Gojenola L, Dao M, Lenta R, Yeakley JM, Schrijver I, Peer J, 1/1/2013
• Assuring the Quality of Next-Generation Sequencing in Clinical Laboratory Practice  
  Gargis AS, Kalman L, Berry MW, Bick DP, Dimmock DP, Hambuch T, Lu F, Lyon E, Voelkerding KV, Zehnbauer BA, Agarwala R, Bennett SF, Chen B, Chin EL, Compton JG, Das S, ..., Nat Biotechnol, 1/1/2012
• Growth of Histoplasma capsulatum isolates is better on potato dextrose agar with chloramphenicol than on brain heart infusion agar  
  Burtelow MA, Merker JD, Baron EJ, J Myc Med, 1/1/2009
• Microarray detection of human parainfluenza 4 infection associated with respiratory failure in an immunocompetent adult  
  Chiu CY, Rouskin S, Koshy A, Urisman A, Fischer K, Yagi S, Schnurr D, Eckburg PB, Tompkins LS, Blackburn BG, Merker JD, Patterson BK, Ganem D, DeRisi JL, Clin Infect Dis, 1/1/2006
• The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells  
  Merker JD, Datta A, Kolodner RD, Petes TD, Genetics, 1/1/2000
• A genetic approach for identifying critical residues in the fingers and palm subdomains of HIV-1 reverse transcriptase  
  Wrobel JA, Chao SF, Conrad MJ, Merker JD, Swanstrom R, Pielak GW, Hutchison CA 3rd, Proc Natl Acad Sci U.S.A., 1/1/1998
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Books/Book Chapters

• Molecular Pathology in Clinical Practice 
  Chapter: T-Cell Lymphomas. 
  Page 603 - 614Merker JD, Arber DAEditors: Leonard DGB.Edition 2nd,2016
• Molecular Diagnostics. 
  Chapter: Molecular diagnostics of hematopoietic disorders. 
  Page 243 - 260Merker JD, Arber DAEditors: Grody WW, Nakamura RM, Kiechle FL, Strom CM.2010

Lectures

• Overview of NGS technology: possibilities and limitations 
  King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
• NGS: CAP checklist and resources 
  King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
• How to select an NGS panel 
  King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/21/2017
• NGS-based methods in hematologic malignancies. 
  King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/20/2017
• Use of clinical exome sequencing in patients with suspected heritable disease. 
  San Francisco, CA - 1/12/2017
• Use of clinical exome and genome sequencing in unexplained heritable disease. 
  King Abdulaziz Medical City, Riyadh, Saudi Arabia - 1/12/2017
• Establishing a clinical genomics program at an academic medical center. 
  University of North Carolina at Chapel Hill, Chapel Hill, NC, 2017; Mayo Clinic, Rochester, MN, 2017 - 1/12/2017
• Clinical genomics and associated quality systems. 
  King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia - 1/11/2017
• Clinical genomics in a CAP-accredited laboratory. 
  Dubai, United Arab Emirates - 1/5/2017
• What is Next Generation Sequencing (NGS)? 
  Dubai, United Arab Emirates - 1/4/2017
• Current and future directions in clinical genomics. 
  Stanford, CA - 1/1/2017
• Advanced Clinical Genomics 
  Stanford University School of Medicine - 1/1/2017
• Clinical Genomics & Personalized Medicine 
  Stanford University School of Medicine - 1/1/2017
• GENE271: Human Molecular Genetics 
  Stanford University School of Medicine - 1/1/2017
• Pathology AP/CP Case Conference 
  Stanford University School of Medicine - 1/1/2017
• Pathology Morning Conference Series 
  Stanford University School of Medicine - 1/1/2017
• Establishing a Clinical Genomics Service at an Academic Medical Center. 
  Maui, HI - 1/27/2016
• Overview of NGS-based oncology testing practices. 
  New Orleans, LA - 1/26/2016
• Google Genomics: Analysis of life science datasets at scale: Running a cloud-based clinical genomics service. 
  San Francisco, CA - 1/24/2016
• Current and future efforts related to the Stanford Medicine Clinical Genomics Service. 
  Stanford University School of Medicine, Stanford, CA - 1/23/2016
• Next-generation sequencing in hematologic malignancies. 
  Houston, TX - 1/10/2016
• Clinical Sequencing. 
  Stanford, CA - 1/5/2016
• Running a cloud-based clinical genomics service. 
  New York, NY - 1/1/2016
• Using genome sequencing in the clinical setting. 
  Mountain View, CA - 1/26/2015
• Clinical Utility of Genome and Exome Sequencing. 
  Chicago, IL - 1/19/2015
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Other

• Charting the Course for Precision Medicine: Adopting consensus analytical standards and streamlining approval pathways for post-market modifications for NGS tests in o... 
  Contributors: Aisner D, Averbuch S, Duncan H, Ferris A, Flaherty KT, Iafrate AJ, Kalamegham R, Kowack E, Lasiter L, Merker J, Schneider E, Stewart M, Tanzella K, Thomae M, Friends of Cancer Research/Alexandria
  1/1/2017
• Use of quantitative PCR in the monitoring of patients with chronic myelogenous leukemia. 
  Merker JD, NewsPath
  http://www.cap.org/apps/docs/newspath/0902/use_of_quantitative_pcr.pdf
  College of American Pathologists - 1/1/2009
• Screening for Lynch syndrome by microsatellite instability analysis and immunohistochemistry. 
  Merker JD, NewsPath
  http://www.cap.org/apps/docs/newspath/0809/screening_for_lynch_syndrome.pdf
  College of American Pathologists - 1/1/2008