JasonRonaldFangusaroMD

PubMed

• 271 citations
  Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, pha...
  Jason Fangusaro, Arzu Onar-Thomas, Tina Young Poussaint, Shengjie Wu, Azra H. Ligon
  The Lancet. Oncology. 2019-05-28
• 2 citations
  Towards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation.
  Ariana M Familiar, Anahita Fathi Kazerooni, Arastoo Vossough, Jeffrey B Ware, Sina Bagheri
  Neuro-Oncology. 2024-09-05
• 5 citations
  Introduction to a special issue on pediatric neuro-oncology.
  Jason Fangusaro, Susan N. Chi
  Journal of Child Neurology. 2009-11-01

Journal Articles

• Prospective Feasibility and Safety of Surgical Biopsy for Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma  
  Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Ge..., Neuro Oncol, 1/5/2018
• Phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC)  
  Banerjee A, Jakacki RI, Onar-Thomas A, Wu S, Nicolaides T, Young Poussaint T, Fangusaro J, Phillips J, Perry A, Turner D, Prados M, Packer RJ, Qaddoumi I, Gururangan S..., Neuro Oncol, 1/28/2017
• Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival  
  Marinoff AE, Ma C, Guo D, Snuderl M, Wright KD, Manley PE, Al- Sayegh H, Sinai CE, Ullrich NJ, Marcus K, Haas-Kogan D, Goumnerova L, London WB, Kieran MW, Chi SN, Fang..., 1/21/2017
• Pediatric Low-Grade Gliomas: Next Biologically Driven Steps  
  Jones DTW, Kieran MW, Bouffet E, Alexandrescu S, Bandopadhayay P, Bornhorst M, Ellison D, Fangusaro J, Fisher MI, Foreman N, Fouladi M, Hargrave D, Hawkins C, Jabado N..., Neuro Oncol, 1/2/2017
• Pediatric low-grade gliomas: implications of the biologic era  
  Packer RJ, Pfister S, Bouffet E, Avery R, Bandopadhayay P, Bornhorst M, Bowers DC, Ellison D, Fangusaro J, Foreman N, Fouladi M, Gajjar A, Haas-Kogan D, Hawkins C, Ho ..., Neuro Oncol, 1/28/2016
• Phase II trial of pegylated interferon alfa-2b in young patients with neurofibromatosis type 1 and unresectable plexiform neurofibromas  
  Jakacki RI, Dombi E, Steinberg SM, Goldman S, Kieran MW, Ullrich NJ, Pollack IF, Goodwin A, Manley PE, Fangusaro J, Allen R, Widemann BC, Neuro Oncol, 1/10/2016
• Consensus on the management of intracranial germ-cell tumours  
  Murray MJ, Bartels U, Nishikawa R, Fangusaro J, Matsutani M, Nicholson JC, The Lancet Oncology, 1/1/2015
• Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis  
  The Lancet Oncology, 1/1/2015
• Successful treatment of metastatic BetaHCG-secreting germ cell tumor occurring 3 years after total resection of a pineal mature teratoma  
  Cardellicchio S, Farina S, Buccoliero AM, Agresti B, Genitori L, de Martino M, Fangusaro J, Sardi I, Eur J Pediatr, 1/21/2014
• Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations  
  Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chorn..., Nat Genet, 1/6/2014
• Involvement of the neural stem cell compartment by pediatric and adult gliomas: a retrospective review of 377 cases  
  Marsh JC, Goldman S, Ziel E, Bregman C, Diaz A, Byrne R, Fangusaro J, J Neurooncol, 1/1/2014
• Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): A Pediatric Brain Tumor Cons...  
  Fangusaro J, Gururangan S, Poussaint TY, McLendon RE, Onar-Thomas A, Warren KE, Wu S, Packer RJ, Banerjee A, Gilbertson RJ, Jakacki R, Gajjar A, Goldman S, Pollack IF,..., Cancer, 1/19/2013
• Unclear standard of care for pediatric high -grade glioma patients  
  Fangusaro J, Warren KE, J Neurooncol, 1/8/2013
• Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas - a Pediatric Brain Tumor Consortium study  
  Gururangan S, Fangusaro J, Poussaint TY, McLendon RE, Onar- Thomas A, Wu S, Packer RJ, Banerjee A, Gilbertson RJ, Fahey F, Vajapeyam S, Jakacki R, Gajjar A, Goldman S,..., Neuro Oncol, 1/4/2013
• Markers of survival and metastatic potential in childhood CNS primitive neuro- ectodermal brain tumours: an integrative genomic analysis  
  Picard D, Miller S, Hawkins CE, Bouffet E, Rogers HA, Chan TS, Kim SK, Ra YS, Fangusaro J, Korshunov A, Toledano H, Nakamura H, Hayden JT, Chan J, Lafay-Cousin L, Hu P..., Lancet Oncol, 1/8/2012
• Pediatric High-Grade Glioma (HGG): a Review and Update on Tumor Clinical Characteristics and Biology  
  Fangusaro J, Frontiers in Pediatric Oncology, 1/1/2012
• Variable response to propranolol treatment of kaposiform hemangioendothelioma, tufted angioma, and Kasabach�Merritt phenomenon  
  Chiu Y, Drolet BE, Blei F, Carcao M, Fangusaro J, Kelly ME, Krol A, Lofgren S, Mancini AJ, Metry DW, Recht M, Silverman RA, Tom WL and Pope E, Pediatr Blood Cancer, 1/1/2012
• Recurrent pure CNS germinoma with markedly elevated serum and cerebrospinal fluid human chorionic gonadotropin-beta (HCGBeta)  
  Khatua S, Phillips A, Fangusaro J, Bovan S, Dhall G, Finlay JL, Pediatr Blood Cancer, 1/1/2011
• Growth Hormone Excess in Children with Neurofibromatosis Type 1- Associated and Sporadic Optic Pathway Tumors  
  Josefson J, Listernick R, Fangusaro JR, Charrow J, Habiby R, J Pediatr, 1/1/2011
• Emergencies in Children and Young Adults with Central Nervous System Tumors  
  Lulla R., Foy A., DiPatri A.J., and Fangusaro J, Clinical Pediatric Emergency Medicine, 1/1/2011
• Non- cerebellar primitive neuroectodermal tumors (PNET): Summary of the Milan consensus and state of the art workshop on marrow ablative chemotherapy with hematopoieti...  
  Fangusaro J, Massimino M, Rutkowski S, Gururangan S, Pediatr Blood Cancer, 1/1/2010
• A 17-year-old boy with fever, sore throat and headache  
  Listernick R, Katz B, Fuleihan R, Cohran V, Liem R, Morgan E, Fangusaro J, Melin-Aldana H, Pediatr Ann, 1/1/2009
• Aggressive Variant of Papillary Glioneuronal Tumor  
  Javahery R., Davidson L., Fangusaro J., Finlay JL, Gonzalez- Gomez, I and McComb G, Journal of Neurosurgery Pediatrics, 1/1/2009
• An introduction to a special edition on Pediatric Neuro-Oncology  
  Fangusaro J and Chi S, J Child Neurol, 1/1/2009
• Pediatric High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas  
  Fangusaro J, J Child Neurology, 1/1/2009
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Books/Book Chapters

• Pediatric Cancer Volume II 
  Chapter: An Overview of Pediatric High grade Gliomas and Diffuse Intrinsic Pontine Gliomas 
  Lulla R. and Fangusaro JEditors: Hayat, Eric.Springer Publishing2012
• Hedgehog signaling in pediatric brain tumors. Hedgehog signaling activation in human cancer and its clinical implications 
  Yoon J., Fangusaro J., Iannaccone P., Walterhouse D.Editors: Xie, Jingwu.2010
• Endocrine Late Effects: Manifestations and Treatments. Late Effects of Treatment for Brain Tumors (Cancer Treatment and Research) 
  Fangusaro J and Littlejohn EEditors: Stewart Goldman and Christopher D. Turner.2009
• Brain Metastases 
  Chapter: Pediatric brain metastasis from extraneural malignancies: a review 
  Page 143 - 168Editors: Raizer and Abrey.2007
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Abstracts/Posters

• Outcomes of a Phase 2 trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System (CNS) Non-Germinomatous Germ Cell Tumors NGGCT): a C...
  Fangusaro J, Wu S, MacDonald S, Murphy E, Shaw D, Bartels U, Khatua S, Boyett J, Williams-Hughes C, Souweidane M, Lu H, Morris D, Panigrahy A, Onar-Thomas A, Fouladi M..., Neuro-Oncology, 1/1/2018
• A Phase II and Re-treatment Study of Selumetinib in Children with Recurrent/Progressive LGG: a Pediatric Brain Tumor Consortium Study
  Fangusaro J, Onar-Thomas A, Poussaint TY, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn L, Pollack IF, Qaddoumi I, Fisher PG, Dhall G, Baxter P, Kreissman..., Neuro-Oncology, 1/1/2018
• A phase II prospective study of selumetinib in children with recurrent or refractory low-grade glioma (LGG: A Pediatric Brain Tumor Consortium Study
  Fangusaro J,� Onar-Thomas A,� Young-Poussaint T,�Wu S, Ligon AH, Lindeman NI, Banerjee A,�Packer R,�Kilburn LB,�Pollack I,�Jakacki R,�Qaddoumi IA, Fisher PG, Dhall G,�..., Journal of Clini Oncology, 1/1/2017
• Bevacizumab-Associated Osteonecrosis of the Wrist and Knee in Three Pediatric Patients with Recurrent Central Nervous System Tumors
  Fangusaro J, Gururangan S, Jakacki RI, Kaste S, Goldman S, Pollack IF, Boyett J and Kun LE, Neuro-Oncology, 1/1/2012
• Evaluating the Incidence and Utility of Microscopic Metastatic Dissemination as Diagnosed by Lumbar Cerebro-Spinal Fluid (CSF) Samples in Children with Newly Diagnosed...
  Fangusaro J, Van Den Berghe C, Tomita T, Rajaram V, Aguilera D and Goldman S, Neuro-Oncology, Vienna, Austria, 1/1/2010
• Thalamic Tumors: The Children�s Memorial Hospital Experience
  Fangusaro J, Echevarria M and Goldman S, Neuro-Oncology, 1/1/2008
• Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed su...
  Fangusaro J, Finlay J, Sposto R, Ji L, Saly M, Zacharoulis S, Asgharzadeh S, Abromowitch M, Olshefski R, Halpern S, Dubowy R, Comito M, Diez B, Kellie S, Hukin J, Rose..., Abstracts from the Twelfth International Symposium on Pediatric Neuro-Oncology. Neuro-oncol, 1/1/2007
• 7-day Continuous Intrathecal Topotecan Infusion for Neoplastic Meningitis: A Pilot Phase I Trial
  Fangusaro J, Leibes L, and Finlay JL, Neuro-Oncology, 1/1/2005
• Bevacizumab (BVZ) Related Toxicities in Children with Recurrent Central Nervous System (CNS) Tumors Treated with BVZ and Irinotecan (CPT-11): a Pediatric Brain Tumor C...
  Fangusaro J, Gururangan S, Jakacki RI, Kaste S, Goldman S, Pollack IF, Boyett J and Kun LE
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Lectures

• A phase II clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors. 
  2019 ASCO Annual Meeting - 6/1/2019
• Targeting MAPK in Pediatric Oncology 
  Chicago, IL - 1/1/2018
• A Phase II and Re-treatment Study of Selumetinib in Children with Recurrent/Progressive LGG: a Pediatric Brain Tumor Consortium Study 
  Denver, CO - 1/1/2018
• Outcomes of a Phase 2 trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System (CNS) Non-Germinomatous Germ Cell Tumors NGGCT): a C... 
  Denver, CO - 1/1/2018
• MAPK targeting in NF-1 Associate Tumors 
  New Orleans, LA - 1/1/2018
• MEK Inhibition in Patients with Newly Diagnosed NF Associated LGG, A COG Trial Concept Update 
  Denver, CO - 1/1/2018
• A phase II prospective study of selumetinib in children with recurrent or refractory low-grade glioma (LGG): A Pediatric Brain Tumor Consortium (PBTC) study 
  1/1/2017
• PBTC-029 Phase I and II Updates 
  Bethesda, MD - 1/1/2017
• A phase I trial of pomalidomide for children with recurrent, progressive/refractory central nervous system (CNS) tumors: A Pediatric Brain Tumor Consortium (PBTC) study 
  Chicago, IL - 1/1/2017
• Phase II Prospective Study of Selumetinib in Children with Recurrent or Refractory NF-Associated Low-grade Glioma (LGG): A Pediatric Brain Tumor Consortium (PBTC) Study 
  1/1/2017
• Updates on LGG MEK Inhibition and PBTC-029 Trial 
  Padova, Italy - 1/1/2016
• Low-Grade Glioma: To BRAF and Beyond 
  Bethesda, MD - 1/1/2016
• Treatment of Supratentorial Primitive Neuroectodermal Tumors 
  Tokyo, Japan - 1/1/2015
• Update on MEK Inhibition Strategies in Low-Grade Glioma 
  Washington, DC - 1/1/2015
• CNS Germ Cell Tumors, a Pediatric Neuro-Oncologist�s Perspective 
  1/1/2014
• CNS Germ Cell Tumors: The North American and Children�s Oncology Group Experience 
  Miami, FL - 1/1/2014
• Bevacizumab (BVZ) Related Toxicities in Children with Recurrent Central Nervous System (CNS) Tumors Treated with BVZ and Irinotecan (CPT-11): a Pediatric Brain Tumor C... 
  Toronto, Canada - 1/1/2012
• Bevacizumab-Associated Osteonecrosis of the Wrist and Knee in Three Pediatric Patients with Recurrent Central Nervous System Tumors 
  Toronto, Canada - 1/1/2012
• Hospice and Palliative Care in Brain Tumor Patients 
  1/1/2011
• Ependymoma: Clinical Behavior and Biologic Aspects 
  Houston, TX - 1/1/2011
• A Review of Pediatric Brain Tumors 
  1/1/2011
• Medulloblastoma, Ependymoma and Clinical Trials 
  Providence, RI - 1/1/2010
• Evaluating the Incidence and Utility of Microscopic Metastatic Dissemination as Diagnosed by Lumbar Cerebro-Spinal Fluid (CSF) Samples in Children with Newly Diagnosed... 
  Vienna, Austria - 1/1/2010
• Overview of Common Pediatric Brain Tumors, including Late Effects of Therapy 
  1/1/2009
• Medulloblastoma and the Head Start sPNET Experience 
  Lutheran General Children�s Hospital, Park Ridge, IL - 1/1/2009
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Other

• Selumetinib in children with recurrent or refractory low-grade glioma 
  ASCO Interview
  1/1/2017
• Co-Developer of Pediatric Neuro-Oncology fellowship website 
  
  http://www.pedsneuro-oncfellowship.org/
  1/1/2015
• Pediatric Brain and Spinal Cord Tumors 
  Pediatric Neuro-Oncology: Ask the Experts
  http://www.youtube.com/watch?v=LZ3ibm8-ZWo
  1/1/2013
• Medulloblastoma 
  Patient Support Resources
  medulloblastoma.org
  1/1/2006
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