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Office
2220 N Druid Hills Rd
Atlanta, GA 30329Phone+1 404-785-7000Fax+1 404-325-6166
Summary
- Dr. Fangusaro has an expertise and specialty training in treating children with central nervous system malignancies, including brain and spinal cord tumors. His primary area of research interest is in the development of clinical trials, novel therapeutics and relevant biologic correlates in pediatric brain tumors in an effort to improve survival outcomes and minimize toxicities. He devotes much of his time to clinical trial research within the Children's Oncology Group (COG), the Pediatric Brain Tumor Consortium (PBTC) and with industry. His main areas of expertise, research and interest within CNS tumors include CNS Germ Cell Tumors, CNS Low Grade Glioma and Early Phase Clinical Trial development. He currently co-leads both the International RAPNO group and the International Coalition on Pediatric low-grade glioma.
Education & Training
- Children's Hospital of Los AngelesFellowship, Pediatric Neuro-Oncology, 2005 - 2006
- Nationwide Children's Hospital/Ohio State UniversityFellowship, Pediatric Hematology/Oncology, 2002 - 2005
- Advocate Health Care/Advocate Children's Hospital (Park Ridge)Residency, Pediatrics, 1999 - 2002
- Loyola University Chicago Stritch School of MedicineClass of 1999
- Loyola University ChicagoB.A., Theatre Arts, 1991 - 1995
Certifications & Licensure
- GA State Medical License 2018 - 2025
- IL State Medical License 2001 - 2020
- CA State Medical License 2005 - 2007
- OH State Medical License 2001 - 2007
- American Board of Pediatrics Pediatrics
- American Board of Pediatrics Pediatric Hematology-Oncology
Awards, Honors, & Recognition
- World's Top 2% Scientists Stanford University, 2023
- Regional Top Doctor Castle Connolly, 2014
- Super Doctor SuperDoctors.com
Clinical Trials
- Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma Start of enrollment: 2006 Aug 01
- Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma Start of enrollment: 2010 Apr 19
- AZD6244 in Children With Low-Grade Gliomas Start of enrollment: 2011 Jun 01
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Publications & Presentations
PubMed
- Pediatric neuro-oncology: Highlights of the last quarter-century.Phoebe Power, Joelle P Straehla, Jason Fangusaro, Pratiti Bandopadhayay, Neevika Manoharan
Neoplasia. 2024-12-04 - Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology consensus review on diagnosis, management, and future directions.Mary Jane Lim-Fat, Julie Bennett, Quinn Ostrom, Mehdi Touat, Enrico Franceschi
Neuro-Oncology. 2024-10-23 - 2 citationsTowards consistency in pediatric brain tumor measurements: Challenges, solutions, and the role of artificial intelligence-based segmentation.Ariana M Familiar, Anahita Fathi Kazerooni, Arastoo Vossough, Jeffrey B Ware, Sina Bagheri
Neuro-Oncology. 2024-09-05
Journal Articles
- Prospective Feasibility and Safety of Surgical Biopsy for Patients with Newly Diagnosed Diffuse Intrinsic Pontine GliomaGupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Ge..., Neuro Oncol, 1/5/2018
- Phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC)Banerjee A, Jakacki RI, Onar-Thomas A, Wu S, Nicolaides T, Young Poussaint T, Fangusaro J, Phillips J, Perry A, Turner D, Prados M, Packer RJ, Qaddoumi I, Gururangan S..., Neuro Oncol, 1/28/2017
- Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survivalMarinoff AE, Ma C, Guo D, Snuderl M, Wright KD, Manley PE, Al- Sayegh H, Sinai CE, Ullrich NJ, Marcus K, Haas-Kogan D, Goumnerova L, London WB, Kieran MW, Chi SN, Fang..., 1/21/2017
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Books/Book Chapters
Abstracts/Posters
- Outcomes of a Phase 2 trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System (CNS) Non-Germinomatous Germ Cell Tumors NGGCT): a C...Fangusaro J, Wu S, MacDonald S, Murphy E, Shaw D, Bartels U, Khatua S, Boyett J, Williams-Hughes C, Souweidane M, Lu H, Morris D, Panigrahy A, Onar-Thomas A, Fouladi M..., Neuro-Oncology, 1/1/2018
- A Phase II and Re-treatment Study of Selumetinib in Children with Recurrent/Progressive LGG: a Pediatric Brain Tumor Consortium StudyFangusaro J, Onar-Thomas A, Poussaint TY, Wu S, Ligon AH, Lindeman N, Banerjee A, Packer RJ, Kilburn L, Pollack IF, Qaddoumi I, Fisher PG, Dhall G, Baxter P, Kreissman..., Neuro-Oncology, 1/1/2018
- A phase II prospective study of selumetinib in children with recurrent or refractory low-grade glioma (LGG: A Pediatric Brain Tumor Consortium StudyFangusaro J,� Onar-Thomas A,� Young-Poussaint T,�Wu S, Ligon AH, Lindeman NI, Banerjee A,�Packer R,�Kilburn LB,�Pollack I,�Jakacki R,�Qaddoumi IA, Fisher PG, Dhall G,�..., Journal of Clini Oncology, 1/1/2017
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Lectures
- A phase II clinical study of pomalidomide (CC-4047) monotherapy for children and young adults with recurrent or progressive primary brain tumors.2019 ASCO Annual Meeting - 6/1/2019
- Targeting MAPK in Pediatric OncologyChicago, IL - 1/1/2018
- A Phase II and Re-treatment Study of Selumetinib in Children with Recurrent/Progressive LGG: a Pediatric Brain Tumor Consortium StudyDenver, CO - 1/1/2018
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Other
- Selumetinib in children with recurrent or refractory low-grade gliomaASCO Interview
1/1/2017 - Co-Developer of Pediatric Neuro-Oncology fellowship website
http://www.pedsneuro-oncfellowship.org/
1/1/2015 - Pediatric Brain and Spinal Cord TumorsPediatric Neuro-Oncology: Ask the Experts
http://www.youtube.com/watch?v=LZ3ibm8-ZWo
1/1/2013 - Join now to see all
Press Mentions
- ContentsFebruary 11th, 2021
- Pediatric Brain Tumor Consortium Adds Members: Dana-Farber, the Hospital for Sick Children, Univ. Of Florida & Nationwide Children’s HospitalSeptember 2nd, 2020
- Activity of Selumetinib in Pediatric Pilocytic Astrocytoma and Low-Grade GliomaJune 6th, 2019
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Committees
- Co-leader, International Coalition on Pediatric LGG 2020 - Present
- Co-Chair, RAPNO 2020 - Present
- Chair, RAPNO LGG International Committee 2018 - Present
- Member, COG CNS Steering Committee 2017 - Present
- Vice-Chair, PBTC Executice Committee 2016 - Present
- Member, International CNS GCT Committee 2013 - Present
- Member, COG CNS Committee 2010 - Present
Professional Memberships
- Society of Neuro-OncologyMember
- Pediatric Brain Tumor ConsortiumMember
- Children's Oncology GroupMember
- Member
Other Languages
- Spanish
Industry Relationships
- Pediatric Educational Speaker's Bureau, DAY ONE2021 - Present
- PEDIATRIC ADVISORY BOARD, ASTRA ZENECA/ALEXION2020 - 2022
- Pediatric Advisory Board, Celgene2016 - 2020
External Links
- Aflac Cancer Centerhttps://winshipcancer.emory.edu/bios/faculty/fangusaro-jason.html
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