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Office
243 Charles St
Boston, MA 02114Phone+1 617-573-3529
Education & Training
- Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolFellowship, Surgical Retina and Vitreous, 2010 - 2012
- Massachusetts Eye and Ear Infirmary/Harvard Medical SchoolResidency, Ophthalmology, 2007 - 2010
- Brigham and Women's HospitalInternship, Internal Medicine, 2006 - 2007
- Harvard Medical SchoolClass of 2006
Certifications & Licensure
- MA State Medical License 2010 - 2026
- American Board of Ophthalmology Ophthalmology
Awards, Honors, & Recognition
- Enhanced Career Development Award Foundation Fighting Blindness
- K12 Mentored Clinical Scientist Development Program Award NIH / National Eye Institute, 2012
- Career Development Award Research for Prevention of Blindness
Publications & Presentations
PubMed
- A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction.Kannan V Manian, Connor H Ludwig, Yan Zhao, Nathan Abell, Xiaoping Yang
Biorxiv. 2025-03-04 - Higher throughput assays for understanding the pathogenicity of variants of unknown significance (VUS) in the RPE65 gene.Leila Azizzadeh Pormehr, Kannan Vrindavan Manian, Ha Eun Cho, Jason Comander
Biorxiv. 2025-02-05 - Systematic empirical evaluation of individual base editing targets: Validating therapeutic targets in USH2A and comparison of methods.Yuki Tachida, Kannan V Manian, Rossano Butcher, Jonathan M Levy, Nachiket Pendse
Molecular Therapy. 2025-01-28
Journal Articles
- Moving Towards PDE6A Gene Supplementation TherapyJason Comander, MD, JAMA Ophthalmology
- Moving Towards PDE6A Gene Supplementation TherapyJason Comander, MD, JAMA Ophthalmology
Press Mentions
- Clinical Challenges: Treating Leber Congenital AmaurosisNovember 29th, 2021
- CRISPR Used Inside a Person’s Body for the First Time EverMarch 6th, 2020
- CLINICAL TRIAL DOWNLOAD: Phase 1/2a Data on Human Retinal Progenitor Cell TherapyMarch 1st, 2020
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Grant Support
- Improving the throughput of diagnosis and treatment of inherited diseases of the retinaMASSACHUSETTS EYE AND EAR INFIRMARY2020–2025
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