JaredSivinski

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PubMed

12 citations
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Andrew J. Ambrose, Christopher J. Zerio, Jared Sivinski, Cody J. Schmidlin, Taoda Shi
Bioorganic & Medicinal Chemistry Letters. 2019-07-15
9 citations
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.
Alex Washburn, Sanofar Abdeen, Yulia Ovechkina, Anne-Marie Ray, Mckayla Stevens
Bioorganic & Medicinal Chemistry Letters. 2019-07-01
21 citations
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
Mckayla Stevens, Sanofar Abdeen, Nilshad Salim, Anne-Marie Ray, Alex Washburn
Bioorganic & Medicinal Chemistry Letters. 2019-05-01