JanNeilBasileMD

Internal Medicine • Charleston, SC

Geriatric Medicine, Cardiology

Professor, Cardiovascular Medicine, Medical University of South Carolina College of Medicine

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Office
109 Bee St
Charleston, SC 29401
Phone+1 843-789-6680

Fax+1 843-805-5798

Summary

A clinical trialist, Clinical Specialist, and Fellow of the American Society of Hypertension and the American Heart Association, I retired as chief of primary care from federal service after 31 years at the Ralph H Johnson VA Medical Center in 2009. I presently run a consultative clinic for resistant and difficult-to control hypertension at MUSC (Medical University of Hypertension) in the division of cardiology. I am a hypertension specialist and currently conduct clinical trials in renal denervation as a means of controlling BP. In addition, I have been involved in large hypertension outcome trials including ALLHAT, ACCORD, SPRINT, ACCOMPLSH, ONTARGET and diabetes including ACCORD and REWIND and most recently, am the US National Leader for the SURPASS-CVOT with Tirzepatide vs Dulaglutide.

Education & Training

Medical University of South CarolinaChief Residency, Internal Medicine, 1981 - 1982
Medical University of South CarolinaResidency, Internal Medicine, 1979 - 1982
Medical University of South CarolinaInternship, Internal Medicine, 1978 - 1979
Virginia Commonwealth University School of MedicineClass of 1978
Johns Hopkins UniversityB.A, Natural Sciences, 1970 - 1974

Certifications & Licensure

SC State Medical License 1979 - 2025
American Board of Internal Medicine Internal Medicine
American Society of HypertensionClinical Specialist in Hypertension

Awards, Honors, & Recognition

Reviewer Joint National Committee 7 Report 2003; ACC/AHA 2017 Hypertension Guideline
Best Doctors in America 2001-2021
Marvin Moser Award for Hypertension American Heart Association, 2019
Fellowship American College of Physicians, 1991
Biltmore’s Who’s Who 2011
Who’s Who in Executives and Professionals 2004-2009, 2010
General Program Chairman Interstate Postgraduate Medical Association, 2000-2008, 2009
ALLHAT 2000 Region 1 Most Outstanding ALLHAT Site 2000
International Advisory Council of the National Medical Association 2000
ASH Specialist in Clinical Hypertension 1999
Honorary Member-Musser Burch Society for Excellence in Patient Care Department of Medicine, Tulane University School of Medicine, 1999
Presenter at Annual Musser-Burch Society Tulane University School of Medicine, 1999
Presenter at 1st VA Annual Hypertension Meeting 1999
Who’s Who in America-National Registry 1999
National Quality Control Awards NHLBI, 1999
Best VA Site NHLBI, 1999
Allhat Allstar Award NHLBI, 1999
Scientific Contribution Award NHLBI, 1999
Special Contribution Award ALLHAT Hypertension Study - Best Medication and Visit Adherence, 1997
President's Club Leadership award Southern Medical Association, 1995, 1996
Excellence in Teaching Award MUSC College of Medicine Students, 1986, 1987, 1988
Hospital Teacher of the Year Award MUSC Department of Family Medicine, 1985
Golden Apple Award 1981
Alpha Epsilon Delta Pre-Medical Honor Society, 1973
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Publications & Presentations

PubMed

36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO.
Michael J Bloch, Ajay J Kirtane, Michel Azizi, Felix Mahfoud, Jan Basile
Hypertension Research. 2024-12-01
3 citations
Managing Hypertension in Older Adults.
Brent M Egan, Holly J Mattix-Kramer, Jan N Basile, Susan E Sutherland
Current Hypertension Reports. 2024-04-01
5 citations
Patient-Level Pooled Analysis of Endovascular Ultrasound Renal Denervation or a Sham Procedure 6 Months After Medication Escalation: The RADIANCE Clinical Trial Program.
Michel Azizi, Andrew S P Sharp, Naomi D L Fisher, Michael A Weber, Melvin D Lobo
Circulation. 2024-03-05

Journal Articles

Granulomatous Infiltration of the Talus and Abnormal Vitamin D and Calcium Metabolism in a Patient with Sarcoidosis: Successful Treatment with Hydrocychloroquine.
DeSimone, D.P., Brilliant,H.L., Basile, J.N., Bell, N.H, Amer. Journal of Med., Vol. 87, pg. 694 696
Variability in Physicians' Decisions on Caring for Chronically Ill Elderly Patients: An International Study.
Thomas, J., Basile, J., et al, Can Med Assoc J:144 (9) p. 1133-1138
Hypertension in the 90's: Newer Aspects of treatment.
Basile, J.N, Clinical Concepts. Southern Medical Association. Vol. 5, No. 1, pg. l-4
Contrasting the Ace Inhibitors. Clinical Concepts.
Basile, J.N, Southern Medical Association. Vol. 5, No. 1, pg. ll-13
Individualized Therapy of Hypertension: A Book Review.
Basile, J.N., Egan, B.M, Circulation, Vol. 93, No. 1 Page 9-l0
Analysis of Recent Papers in Hypertension.
Basile, J.N, The Journal of Clinical Hypertension., Vol. 1, Number 1
Dissecting the JNC 6 Report for the Primary Care Physician.
Basile, Jan N. and Wang, Bo, Family Practice Recertification. Vol 21, No. 12, Page 89-104
Analysis of Recent Papers in Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Vol I, No. II
Analysis of Recent Papers In Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Vol I, No III,Page 233-235
SMA’s Third Annual Conference on Hypertension: Improving Outcomes in Primary Care.
Basile, Jan, Southern Medical Journal Vol 93, No 5, Page 527-545
Analysis of Recent Papers in Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Volume II, No. I, page 56-59
Analysis of Recent Papers in Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Volume II, No. II, page 144-148
Analysis of Recent Papers in Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Vol II No. III, page 227-232
Analysis of Recent Papers In Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Vol II No. IV, page 290-294
Analysis of Recent Papers In Hypertension.
Basile, Jan and Brzezinski, Walter, The Journal of Clinical Hypertension. Vol II No.V, page 349-355
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol II No. VI page 415-421
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol III Number I page 54- 59
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Volume III Number II Page 120-125
New Strategies for Improving Heart Failure Management: A Primary Care Perspective.
Basile, Jan, Southern Medical Journal Vol 94. No.2 page 166-174
ACE Inhibitors in the Treatment of African-American Patients with Heart Failure.
Ofili, E., Flack, J., Gibbons, G., Mensah, G., Valentine, H., Ferdinand, K., Basile, J., Curry, C., Weir, M., Saunders, E, Urban Cardiology. Vol.8, No.3 pg 11-12
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol III Number III Page 184-195
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol. III Number IV pg. 256-260
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol. III Number V. Pg 313-318
Analysis of Recent Papers in Hypertension.
Basile, Jan, The Journal of Clinical Hypertension. Vol. III Number VI. Pg 376-379
Neutraceuticals and Vascular Biology: Are They Ready For Prime Time Use?
Basile, J, Journal of the American Neutraceutical Association. Supplement No.1 page 3-4
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Books/Book Chapters

Hot Topics in Hypertension.
Chapter: An Evidence-Based Approach to Selecting Initial Antihypertensive Therapy
Page 231 - 235Basile JHanley and Belfus, Inc, Philadelphia, Pennsylvania
Hypertension in Older Patients: A Companion Text to Braunwald’s Heart Disease.
Page 349 - 355Bloch Michael J and Basile Jan NEditors: Henry Black and William Elliott.
Hypertension: A Companion Text to Braunwald’s Heart Disease.
Chapter: Hypertensive Emergencies and Urgencies
Page 390 - 395Elliott William J, Rehman S, Vidt D, and Basile JEditors: Black and William Elliott.Elsevier
Evidence-Based management of hypertension.
Chapter: Evidence-based Management of Hypertension: How Much Should You Reduce Blood Pressure?
Page 1 - 14Basile Jan and Moser MarvinEditors: Matthew R Weir.Tfm Publishing Limited, Shrewsbury, UK
Clinical Challenges in Hypertension II.
Chapter: Management of Hypertensive Emergencies
Page 77 - 90Rehman S, Vidt D, and Basile JEditors: Peter P Toth and Domenic A. Sica.Atlas Medical Publishing. Ltd, Oxford, England
Hypertension Primer.
Chapter: Treatment of the Elderly Hypertensive: Systolic Hypertension
Page 485 - 488Basile, JanEditors: Izzo, Sica, Black.American Heart AssociationEdition 4th,
Hypertensive Emergencies and Urgencies Clinical Hypertension: A Companion to Braunwald’s Heart Disease.
Page 517 - 523Rehman S, Basile J, and Vidt DEditors: Henry Black and William Elliott.Saunders
Hypertension: A Companion to Brenner and Rector's The Kidney.
Chapter: Hypertension in the Elderly
Page 579 - 586Basile JN, Meyer RPEditors: Oparil S, Weber MA.Elsevier, Philadelphia
ACP Key Disease Series.
Chapter: Principles of Hypertension Treatment. How Low Should You Go?
Page 51 - 63Basile, J and Moser, MAmerican College Of Physicians Books
Adherence to Long-Term Therapies. Evidence for Action.
Chapter: Hypertension
Page 107 - 114Basile, JWorld Health Organization Publications
New Therapeutic Approaches to Hypertension: Results of JNC IV Report.
Basile, J.NEditors: C.J. Pepine.Dial Access, Southern Medical Association
Hot Topics in Hypertension.
Chapter: Management of Renovascular Hypertension
Page 325 - 334Bloch M, and Basile JHanley and Belfus, Inc, Philadelphia, Pennsylvania
Hypertension: Modifying its Risk in Special Populations.
Chapter: Southern Medical Association Publications
Basile, J.NClinical Concepts
Hot Topics in Hypertension.
Egan BM, Basile J, Lackland DHanley and Belfus, Inc, Philadelphia, Pennsylvania
Hypertension Primer.
Chapter: Treatment of the Elderly Hypertensive: The Importance of Systolic Elevation
Page 446 - 449Basile, JanEditors: Izzo and Black.American Heart AssociationEdition 3rd,
Heart Failure: From Clinical Data to Clinical Practice.
Chapter: Heart Failure: The Scope of the Problem and the Primary Care Physician’s Role
Page 3 - 6Basile, JanYardley Communications, Yardley, Pennsylvania
Metabolic Consequences of Diuretic Therapy.
Basile, J.NEditors: C.J. Pepine.Dial Access, Southern Medical Association
Hyperlipidemia: A Practical Approach.
Chapter: Dial Access, Southern Medical Association
Basile, J.NEditors: C.J. Pepine.
Hypertension: The Role of Ace Inhibitors.
Basile, J.NEditors: C.J. Pepine.Dial Access, Southern Medical Association
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Abstracts/Posters

Metastatic Gastroesophageal Adenocarcinoma to Skeletal Muscle-A Unique Event.
Basile, Jan, 95th Annual Assembly of the Southern Medical Association, Nashville, Tennessee
Preventing The First and Subsequent Stroke:Utilizing the Newest Evidence.
Basile, Jan N, The Southern Medical Association Annual Meeting Symposia Highlights, Medical Association Communications. Yardley, Pennsylvania
Heart Failure: From Clinical Data to Clinical Practice.
Basile, Jan N, Medial Association Communications, Yardley, Pennsylvania
International Medical Graduates and AAMC Partership for Success.
Rehman S, Basile J, Wolensky A, and Wolfman T, Annual Meeting of the SGEA, Miami, Florida
Risk Factor Treatment and Control in the Stroke Belt.
Egan B, Basile J, Lackland D, American Journal of Hypertension. Vol 16, No. 5, Part 2, pg 8A
Ethnic Differences in Risk Factor Control Among Diabetic Hypertensives.
Egan B, Basile J, Cheek D, Lackland D, American Journal of Hypertension. Vol 16, No. 5, Part 2, pg 208A
Blood Pressure Control By Randomized Drug Group In ALLHAT.
William C. Cushman, Charles E. Ford, Paula Einhorn, Jackson T.Wright, Jr., Richard A. Preston, Barry R. Davis, Jan N. Basile, Am J Hypertension, Vol 17, No 5, Suppl 1, Page S30
Hemochromotosis presenting as Osteoarthritis.
Rehman SU, Basile JN, Clyburn EB, Southern Med Journal; 96 S:23
Risk and Impact of IncidentGlucose Disorders in Hypertensive Older Adults Treated with an ACE Inhibitor, a Calcium Channel Blocker, or a Diuretic: A Report from the AL...
Barzilay J, Pressel S, Davis B, Margolis K, Cutler J, Ong S, Basile J, Sadler L, Summerson J, Whelton P, Am J Hypertension, Vol 17, No 5, Suppl 1, Page S1
Treatment and Control of Hypertension in the Veterans Health Administration.
Furmaga E, Cunningham F, Cushman W, Glassman P, Basile J, Dong D, Katz L, Rutan G, Am J Hypertension, Vol 17, No 5, Suppl 1,Page S107
Treatment and Control of Hypertension & Associated Risk Factors at VA & non-VA Outpatient Clinics.
Egan B, Basile J, Lackland D, Hutchison F, Am J Hypertension, Vol 17, No 5, Suppl 1, Page S38, Medical University of South Carolina and Ralph H. Johnson V.A. Medical Center, Charleston, SC
Evidence for Extra Renal Production of 1,25 D:(OH)2 Vitamin D in Patients with Active Sarcoidosis and Normal Calcium Metabolism.
Basile, Jan, Tenth Annual Scientific Meeting, American Society for Bone and Mineral Research, New Orleans, Louisiana
Increased calcium intake does not suppress circulating l,25- Dihydroxyvitamin D in normocalcemic patients with sarcoidosis.
Basile, Jan, Annual Meeting Southern Medical Association, San Antonia, Texas
Treatment Retinoid - Induced Hyperlipidemia.
Basile, Jan, American Academy of Dermatology, 53rd Annual Meeting, New Orleans, LA
Low Molecular Weight Heparin Reduces Hospital Stay for Thigh Deep Vein Thrombosis.
Basile, Jan, 91st Annual Meeting Southern Medical Association, Charlotte, North Carolina
B-Blockers:New Ammunition for the Fight Against Heart Failure.
Basile, Jan and Williams, Randall, Interactive network for Continuing Education, Monmouth Junction, NJ
Difficult Clinical Cases/Workshop.
Basile, Jan, Seventeenth Annual Session of the American Society of Hypertension, New York City, NY
First-line aliskerin/hydrochlorthiazide combination therapy lowers BP more effectively than hydrochlorthiazide alone in elderly patients with systolic BP 180-190 mmHg ...
Basile Jan, Babazadeh S, Lillestol Michael, et al, The Journal of Clinical Hypertension Volume 12, Supplement 1,Page A23
Effects of Intensive Blood pressure Control on Cardiovascular Events in Type 2 Diabetes Mellitus.
Basile, Jan, Cushman William C, ACCORD Blood Pressure Trial
First- line aliskerin/hydrochlorthiazide combination therapy lowers BP in Older Patients with Stage 2 Hypertension and Metabolic Syndrome or Diabetes.
Basile Jan, Babazadeh S, Lillestol Michael, et al, American Society of Hypertension meeting
Apparent Tratment Resistant Hypertension in a Community Based Practice Network.
Egan Brent, Zhao Yumin, Brzezinski Adam, Clyburn Ben, Basile Jan, Lackland Daniel, Journal of Clinical Hypertension Vol 13, Suppl 1 pg A125
Aliskerin/Hydrochlorthiazide Combination Therapy Lowers Central Aortic Blood Pressure More Effectively Than Hydrochlorthiazide Alone in Older Patients with Stage 2 Hyp...
Basile, Jan, European Society of Hypertension meeting
Efficacy of Combined Therapy with Nebivolol and Lisinopril Compared with the Individual Agents.
Weber Michael, Basile Jan, Stapff M et al, American Society of Hypertension meeting, New York, New York
With So Many Effective Classes of Drugs, Why Can’t We Improve Blood Pressure Control?
Basile J, Rehman S, Vidt D, Workshop Session. Annual Meeting of the Society of General Internal Medicine, Vancouver, Canada
Risk and Impact of Incident Glucose Disorders in Hypertensive Older Adults Treated with an ACE Inhibitor, a Calcium Channel Blocker, or a Diuretic: A Report from the A...
Barzilay J, Pressel S, Davis S, Margolis K, Ong S, Basile J, Sadler L, Summerson J, Whelton P, American Society of Hypertension
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Lectures

4th Annual Essentials in Primary Care Summer Conference - Session 2
Continuing Education Company Inc, Kiawah Island, South Carolina - 7/29/2013
4th Annual Essentials in Primary Care Summer Conference - Session 1
Continuing Education Company Inc, Palm Coast, Florida - 7/22/2013
17th Annual Conference on Hypertension - Focus on Hypertension, Diabetes and Dyslipidemia
Continuing Education Company Inc, Charleston, South Carolina - 6/28/2013
7th Annual Primary Care Spring Conference Session 2
Continuing Education Company Inc, Palm Coast, Florida - 4/1/2013
7th Annual Primary Care Spring Conference Session 1, Palm Coast, Florida - International Puppy Doctors Consortium
Continuing Education Company Inc, Palm Coast, Florida - 3/25/2013
Essentials in Primary Care Live CME 2012 Conference Florida Keys
Continuing Education, Inc., Duck Key, Florida - 11/5/2012
3rd Annual Essentials in Primary Care Fall Conference 2012
Continuing Education Company Inc, Duck Key, Florida - 11/5/2012
2nd Annual Primary Care Live CME 2012 Conference
Continuing Education, Inc., Lahaina, Hawaii - 10/22/2012
3rd Essentials in Primary Care CME Summer Conference Palm Coast Florida Session Two
Continuing Education Company Inc, Palm Coast, Florida - 7/30/2012
16th Annual Hypertension Conference: Focus on Hypertension, Diabetes & Dyslipidemia
Continuing Education Company Inc, Palm Coast, Florida - 7/27/2012
3rd Essentials in Primary Care Summer CME Palm Coast Florida Session One
Continuing Education Company Inc, Palm Coast, Florida - 7/23/2012
6th Annual Primary Care Spring CME Conference Week 2 Palm Coast Florida
Continuing Education Company Inc, Palm Coast, Florida - 4/9/2012
6th Annual Primary Care Spring CME Conference - Palm Coast, Florida
Continuing Education Company Inc, Palm Coast, Florida - 4/2/2012
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Other

Clinical Controversies in the Management of Cholesterol.
Basile, Jan, Veterans Administration/Southern Medical Association REMEC
Birmingham, Alabama
Improving Patient Outcomes: Hypertension.
Basile, Jan, Audio-Digest Internal Medicine Volume 50, Issue 04
Clinical Pearls in Hypertension.
Basile, Jan, Audio-Digest Family Practice Volume 51, Issue 14
Should the African-American Patient be Denied Renin-Angiotensin System Blockade.
Basile, Jan, Southern Medical Association 96th Annual Meeting
Washington, DC
Metabolic Syndrome.
Basile, Jan, Audio-Digest Family Practice Volume 53, Issue 22
Advances in Hypertension.
Basile, Jan, Audio-Digest Internal Medicine From Interstate Postgraduate Medical Association Primary Care Update.
Hypertension Today. Treating the Elderly: The Importance of Systolic and Pulse Pressures.
Basile, Jan, Audio Digest Vol. 49, Issue 07
Hypertension Today. Treating Hypertension in Diabetic Patients.
Basile, Jan, Audio Digest Vol. 49, Issue 07
Geriatric Cardiology. Cardiovascular Concerns-Lipids and Hypertension.
Basile, Jan, Audio Digest. Vol.50, Issue 20
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Press Mentions

Better Methods to Diagnose and Treat Chronic HypertensionOctober 18th, 2022
Highlights from the American Heart Association's Joint Hypertension 2018 Scientific SessionsMarch 5th, 2019
Primary Care Continuing Medical Education Conference (CME) Faculty Listing Released for the 5th Annual Primary Care Fall Conference on Maui, HawaiiAugust 18th, 2015
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Professional Memberships

American Soceity of Hypertension
Fellow
American Heart Association - AHA
Fellow