JamesTweddellMD

PubMed

• Hemostatic derangements associated with cardiopulmonary bypass predict outcomes in pediatric patients undergoing corrective heart surgery.
  Kevin Todd, Spencer J Hogue, James S Tweddell, James A Reagor, Eric Mullins
  Journal of Thrombosis and Haemostasis. 2024-11-12
• 1 citations
  Factor XII promotes the thromboinflammatory response in a rat model of venoarterial extracorporeal membrane oxygenation.
  Mousa Kharnaf, Farhan Zafar, Spencer Hogue, Leah Rosenfeldt, Rachel L Cantrell
  The Journal of Thoracic and Cardiovascular Surgery. 2024-08-01
• 8 citations
  Contemporary Relationship Between Hospital Volume and Outcomes in Congenital Heart Surgery.
  Karl F Welke, Tara Karamlou, Sean M O'Brien, Joseph A Dearani, James S Tweddell
  The Annals of Thoracic Surgery. 2023-12-01

Journal Articles

• Valve-Sparing Aortic Root Replacement in Loeys-Dietz Patient with Anomalous Aortic Origin of the Right Coronary Artery  
  James Tweddell, MD, CTSNet
• Is There an Optimal Organ Acceptance Rate for Pediatric Heart Transplantation: “A Sweet Spot”?  
  Clifford Chin, Chet R Villa, Angela Lorts, Farhan Zafar, James S Tweddell, Pediatric Transplantation
• Are Complex Aortic Valve Repairs a Real Alternative to Replacement in Children?  
  James Tweddell, MD, European Journal of Cardio-Thoracic Surgery
• Invited commentary on: In search of the ideal pulmonary blood source for the Norwood procedure: a meta-analysis and systematic review Sharma V, Deo SV, Huebner M, Dear...  
  Tweddell JS, Ann Thorac Surg, 1/1/2014
• Anterior Tracheal Suspension for Tracheobronchomalacia in Infants and Children  
  Mitchell ME, Rumman N, Chun RH, Rao A, Martin T, Beste DJ, Berens RJ, Parakininkas DE, Ghanayem NS, Hubert MJ, Uhing M, Simpson P, Sato TT, Tweddell JS, Kerschner JE, Ann Thorac Surg, 1/1/2014
• Prevention and treatment of thrombosis in pediatric and congenital heart disease: a scientific statement from the American Heart Association American Heart Association...  
  Giglia TM, Massicotte MP, Tweddell JS, Barst RJ, Bauman M, Erickson CC, Feltes TF, Foster E, Hinoki K, Ichord RN, Kreutzer J, McCrindle BW, Newburger JW, Tabbutt S, To..., Circulation, 1/17/2013
• Current cardioplegia practice in pediatric cardiac surgery: a north american multiinstitutional survey  
  Kotani Y, Tweddell J, Gruber P, Pizarro C, Austin EH 3rd, Woods RK, Gruenwald C, Caldarone CA, Ann Thorac Surg, 1/1/2013
• Construction of the Right Ventricle-to-Pulmonary Artery Conduit in the Norwood: The �Dunk� Technique  
  Tweddell JS, Mitchell ME, Woods RK, Spray TL, Quintessenza JA, Operative Techniques in Thoracic and Cardiovascular Surgery, 1/1/2012
• Variation in perioperative care across centers for infants undergoing the Norwood procedure  
  Pasquali SK, Ohye RG, Lu M, Kaltman J, Caldarone CA, Pizarro C, Dunbar-Masterson C, Gaynor JW, Jacobs JP, Kaza AK, Newburger J, Rhodes JF, Scheurer M, Silver E, Sleepe..., J Thorac Cardiovasc Surg, 1/1/2012
• Policy Statement From the American Academy of Pediatrics, SECTION ON CARDIOLOGY AND CARDIAC SURGERY: Pediatric Sudden Cardiac Arrest  
  Campbell R, Berger S, Ackerman MJ, Morrow WR, Jenkins K, Minich LL, Rosenthal GL, Snyder CS, Tweddell J, Beekman RH, Klitzner TS, Manning PB, Towbin JA, Mital S, Pediatrics, 1/1/2012
• Report of the pediatric heart network and national heart, lung, and blood institute working group on the perioperative management of congenital heart disease  
  Kaltman JR, Andropoulos DB, Checchia PA, Gaynor JW, Hoffman TM, Laussen PC, Ohye RG, Pearson GD, Pigula F, Tweddell J, Wernovsky G, Del Nido P, Perioperative Working G..., Circulation, 1/1/2010
• Humoral rejection after pediatric heart transplantation: a case report  
  Stendahl G, Berger S, Ellis T, Gandy K, Mitchell M, Tweddell J, Zangwill S, Prog Transplant, 1/1/2010
• Partial and transitional atrioventricular septal defect outcomes  
  Minich LL, Atz AM, Colan SD, Sleeper LA, Mital S, Jaggers J, Margossian R, Prakash A, Li JS, Cohen MS, Lacro RV, Klein GL, Hawkins JA, Pediatric Heart Network Investig..., Ann Thorac Surg, 1/1/2010
• Hypersensitivity reactions to aprotinin re-exposure in paediatric surgery  
  Siehr S, Stuth E, Tweddell J, Hoffman G, Troshynski T, Jones D, Mitchell M, Ghanayem N, Eur J Cardiothorac Surg, 1/1/2010
• Inclusion of Hepatic Venous Drainage in Patients with Pulmonary Arteriovenous Fistulas  
  Tweddell JS, Invited commentary on: Kim SJ, Bae EJ, Lee JY, Lim HG, Lee C, Chang-Ha Lee CH, Ann Thorac Surg, 1/1/2009
• Design and rationale of a randomized trial comparing the Blalock-Taussig and right ventricle-pulmonary artery shunts in the Norwood procedure  
  Ohye RG, Gaynor JW, Ghanayem NS, Goldberg CS, Laussen PC, Frommelt PC, Newburger JW, Pearson GD, Tabbutt S, Wernovsky G, Wruck LM, Atz AM, Colan SD, Jaggers J, McCrind..., J Thorac Cardiovasc Surg, 1/1/2008
• Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats  
  Baker JE, Su J, Hsu A, Shi Y, Zhao M, Strande JL, Fu X, Xu H, Eis A, Komorowski R, Jensen ES, Tweddell JS, Rafiee P, Gross GJ, Cardiovasc Res, 1/1/2008
• in the preoperative management of infants with hypoplastic left heart syndrome  
  Johnson BA, Mussatto K, Uhing MR, Zimmerman H, Tweddell JS, Ghanayem N, Pediatr Cardiol, 1/1/2008
• Practical application of the virtual crossmatch  
  Zangwill S, Ellis T, Stendahl G, Zahn A, Berger S, Tweddell JS, Pediatr Transplant, 1/1/2007
• Identification, imaging, functional assessment and management of congenital coronary arterial abnormalities in children  
  Friedman AH, Fogel MA, Stephens P Jr, Hellinger JC, Nykanen DG, Tweddell JS, Feltes TF, Rome JJ, Cardiol Young, 1/1/2007
• The vertical vein to ligate or not to ligate?  
  Tweddell JS, J Thorac Cardiovasc Surg, 1/1/2007
• Right ventricle to pulmonary artery conduit versus Blalock-Taussig shunt: a hemodynamic comparison  
  Ghanayem NS, Jaquiss RDB, Cava JR, Frommelt PC, Mussatto KA, Hoffman GM, Tweddell JS, Ann Thorac Surg, 1/1/2006
• Quality of life following surgery for congenital cardiac malformations in neonates and infants  
  Mussatto K, Tweddell JS, Cardiology in the Young, 1/15/2005
• The Norwood Procedure with an Innominate Artery-to-Pulmonary Artery Shunt  
  Tweddell JS, Operative Techniques in Thoracic and Cardiovascular Surgery, 1/1/2005
• Complex aortic valve repair provides a durable and effective alternative to valve replacement in children with aortic valve disease  
  Tweddell JS, Pelech AN, Frommelt PC, Jaquiss RDB, Hoffman GM, Mussatto KA, Litwin SB, J Thorac Cardiovasc Surg, 1/1/2005
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Books/Book Chapters

• Hemodynamics and Cardiology: Neonatology Questions and Controversies 
  Chapter: Regional Blood Flow Monitoring in the Perioperative Period 
  Hoffman GM, Tweddell JSElsevierEdition 2nd,2012
• Cardiothoracic Surgery Review 
  Chapter: Tetralogy of Fallot (TOF), including TOF with pulmonary stenosis (PS), pulmonary atresia (PA) and TOF with PA and major aortopulmonary collateral arteries (MAPCAs) 
  Barnes ME, Tweddell JS, Mitchell MEEditors: Kenneth L. Franco & Vinod H. Thourani.Lippincott Williams & Wilkins2011
• Cardiothoracic Surgery Reivew 
  Chapter: Pulmonary Atresia with Intact Ventricular Septum 
  Mitchell ME, Barnes ME, Tweddell JSEditors: Kenneth L. Franco & Vinod H. Thourani.Lippincott, Williams & Wilkins2011
• Moss and Adams� Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult 
  Chapter: Hypoplastic Left Heart Syndrome 
  Tweddell JS, Hoffman GM, Ghanayem NS, Frommelt MA, Mussatto KA, Berger SEditors: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF.Lippincott, William and Wilkins Publishers, Philadelphia, PAEdition 8th,2011
• Paediatric Cardiology 
  Chapter: Surgical Techniques 
  Gandy KL, Hoffman GM, Van der Wal P, Tweddell JSEditors: Anderson, Baker, Penny, Redington, Rigby, & Wernovsky.Edition 3rd,2010
• Moss and Adams' Heart Disease in Infants, Children, and Adolescents: Including the Fetus and Young Adult 
  Chapter: Hypoplastic Left Heart Syndrome 
  Tweddell JS, Hoffman GM, Ghanayem NS, Frommelt MA, Mussatto KA, Berger SEditors: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF.Lippincott, William and Wilkins Publishers, Philadelphia, PAEdition 7th,2007
• The Pediatric Clinic of North America 
  Chapter: Recent advances in the surgical management of the single ventricle pediatric patient 
  Tweddell JS, Litwin SB, Thomas JP, Mussatto KMEditors: Berger S.WA Saunders Co. Publishers, Philadelphia, PA1999
• Mastery of Cardiothoracic Surgery 
  Chapter: Aortopulmonary Window 
  Tweddell JSEditors: Kaiser LR, Kron IL, Spray TL.Lippincott-Raven Publishers, Philadelphia, PA1997
• Cardiac Mapping 
  Chapter: Potential distribution mapping of ventricular tachycardia 
  Boineau JP, Schuessler RB, Eisenberg SB, Tweddell JS, Harada A, Rokkas CK, Cox JLEditors: Shenasa M, Borggrefe M and Breithardt G.Futura Publishing, Co., Mount Kisco, NY1993
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Abstracts/Posters

• Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries - Children's Hospital of Wisconsin Experience
  Tweddell JS, Jacobsen RM, Woods R , Mitchell M, Cava J, Ghanayem N, Frommelt P, Bartz P, Annual Congenital Heart Surgeons� Society Meeting, 1/25/2015
• Effect of intercurrent operation and systemic hemodynamics on developmental trajectory in infants and children with congenital heart disease
  Hoffman GM, Mussatto KM, Brosig Soto C, Bear L, Tweddell JS, Society of Thoracic Surgery, 51st Annual Meeting, 1/1/2015
• The Supported modified-Ross Operation: Early Outcomes and Intermediate Follow Up
  Jacobsen R, Earing E, Hill G, Barnes M, Tweddell J, American Academy of Pediatrics, National Conference and Exhibition, 1/1/2014
• The Supported (Ross Ungerleider) Modified Ross Operation: Early Outcomes And Intermediate Follow Up
  Jacobsen R, Earing E, Hill G, Barnes M, Tweddell J, Southern Thoracic Surgical Association, 61st Annual meeting, 1/1/2014
• Risk Factors for Abnormal Developmental Trajectories in Young Children with Congenital Heart Disease
  Mussatto K, Hoffmann R, Hoffman G, Bear L, Tweddell J, Cao Y, Brosig C, American Heart Association, Scientific Sessions, 1/1/2014
• Pulmonary and Cardiac Partitioning of Gas Exchange Abnormality and Alveolar Deadspace in Neonates After the Stage 1 Palliation
  Hoffman MG, Stuth EA, Scott JP, Ghanayem NS, Tweddell JS, Mussatto KM, Anesthesiology, 1/1/2014
• Mechanical Circulatory Support and Outcomes of Pediatric Heart Transplantation
  Niebler RA, Egodage SN, Ghanayem NS, Berger S, Shah TK, Woods RK, Mitchell ME, Tweddell JS, Zangwill SD, Thoracic Surgical Association, 60st Annual meeting, 1/1/2013
• Gut Microbiome Metabolic Phenotypes are Biomarkers for Severity of Myocardial Infarction
  Baker JE, Lam V, Su J, Tweddell JS, Salzman NH, Gross GJ, Circulation, 1/1/2013
• Hemodynamic Effects of alpha-Adrenergic Blockade With Phentolamine Following Stage One Palliation of Hypoplastic Left Heart Syndrome
  Hoffman GM, Mussatto KA, Tweddell JS, Ghanayem NS, Circulation, 1/1/2013
• Perioperative Global and Regional Hemodynamic Assessment With NIRS Predicts Outcome After Neonatal Arterial Switch Operation
  Hoffman GM, Ghanayem NS, Mussatto KA, Lamers LJ, Tweddell JS, Anesthesiology, 1/1/2013
• Aortic valve replacement in neonates and infants: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database
  Woods RK, Pasquali SK, Jacobs ML, Austin EH, Jacobs JP, Krolikowski M, Mitchell ME, Pizarro C, Tweddell JS, American Association for Thoracic Surgery 92nd Annual Meeting, 1/1/2012
• Increased Use of Recombinant Activated Factor VII and Need for Re-Exploration in Infants Undergoing Major Congenital Heart Surgery
  Scott JP, Stuth EA, Hoffman GM, Berens RJ, Punzalan RC, Costigan D, Simpson P, Dasgupta M, Tweddell JS, Anesthesiology, 1/1/2012
• Outcomes after Pediatric Heart Transplantation with Use of the Berlin Heart EXCOR Pediatric Ventricular Assist Device
  Eghtesady P, Almond C, Tjossem C, Epstein D, Imamura M, Turrentine M, Tweddell J, Jaquiss R, Canter CE, Circulation, 1/1/2012
• Risk Factors for Mortality and Transplantation in the Single Ventricle Reconstruction Trial: Beyond Shunt Type
  Tweddell JS, Sleeper LA, Ohye RG, Williams IA, Mahony L, Pizarro C, Pemberton VL, Frommelt PC, Bradley SM, Cnota JF, Hirsch J, Kirshbom P, Li JS, Pike N, Puchalski M, ..., Circulation, 1/1/2011
• Outcomes of Children Supported with the Berlin Heart EXCOR Pediatric VAD: Impact of Patient Characteristics at Implant on Mortality
  Almond C, Morales D, Buchholz H, Turrentine M, Imamura M, Massicotte P, Tweddell JS, Devaney E, Jordan L, Kanter K, Holman W, Cohen G, St. Louis J, Nguyen K, Ravishank..., Circulation, 1/1/2011
• Improving Interstage Survival After Norwood Operation: Outcomes Following 10 Years of Home Monitoring
  Rudd RA, Frommelt MA, Hehir DA, Slicker JA, Mussatto KA, Tweddell JS, Bartz PJ, Ghanayem NS, Circulation, 1/1/2011
• Human Genome Copy Number Spectra Analysis in Congenital Heart Malformations
  Tomita-Mitchell A, Mahnke DK, Struble CA, Tuffnell ME, Hidestrand M, Stoddard AJ, Harris S, Goetsch MA, Lorier RB, Simpson PM, Bick DP, Broeckel U, Pelech AN, Tweddell..., Circulation, 1/1/2011
• Cause, Timing and Location of Death in the Single Ventricle Reconstruction Trial
  Ohye RB, Schonbeck JV, Eghtesady P, Laussen PC, Pizarro C, Shrader P, Frank DU, Graham EM, Hill KD, Jacobs JP, Kanter KR, Kirsh JA, Lambert LM, Lewis AB, Ravishankar C..., American Heart Association Scientific; Circulation, 1/1/2011
• Effect of pH Strategy on Antegrade Cerebral Perfusion on Postoperative Cerebral Autoregulation
  Hoffman GM, Stuth EA, Berens RJ, Groneck JM, Tweddell JS, American Society of Anesthesiology, San Diego, CA, 1/16/2010
• Increased Recombinant Factor VIIa Usage in the Post-Aprotinin Era
  Scott JP, Punzalan R, Niebler RA, Tweddell JS, Costigan D, American Society of Anesthesiology, San Diego, CA, 1/16/2010
• The Kinetics of the Development of Ventricular Dysfunction in Patients with Hypoplastic Left Heart Syndrome
  Underkofler H, Frommelt M, Fedderly RT, Simpson PM, Mitchell ME, Tweddell JS, Gandy KL, American Association for Thoracic Surgery, 90th Annual Meeting, Toronto, Ontario, Canada, 1/3/2010
• Interstage growth velocity after the Norwood procedure can parallel infant growth through home monitoring and standardized feeding plans
  Hehir DA, Rudd N, Slicker J, Mussatto KA, Frommelt MA, Tweddell JS, Ghanayem NS, American Academy of Pediatrics, San Francisco, CA, 1/2/2010
• Routine developmental follow-up for children with congenital heart disease
  Brosig-Soto C, Olude O, Dasgupta M, Hoffman R, Bear L, Krolikowski M, Tweddell JS, Mussatto KA, American Academy of Pediatrics, San Francisco, CA, 1/1/2010
• Correlation of thromboelastography with postoperative bleeding following congenital heart surgery
  Chaplin RN, Gill JA, Brabant CP, Mitchell ME, Gandy KL, Tweddell JS, Stuth EA, Ghanayem NS, The Society of Thoracic Surgeons, 45th Annual Meeting, San Francisco, CA, 1/26/2009
• Modified pH Strategy during Antegrade Cerebral Perfusion Improves Cerebral Hemodynamics
  Hoffman GM, Groneck JM, Mussatto KA, Stuth EA, Tweddell JS, American Society of Anesthesiology, New Orleans, LA, 1/17/2009
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Lectures

• Team Cincinnati 
  2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
• Repair of Conotruncal Anomolies in Heterotaxy 
  Cleveland, OH - 1/28/2018
• Strategy for Neonatal Congenital Heart Surgery 
  Cleveland, OH - 1/27/2018
• Surgical Management of Ebstein's Anomaly 
  Phoenix, AZ - 1/22/2018
• Public Reporting of Congenital Heart Surgery Outcomes: What can New York State Teach the Rest of the Country? 
  Cohen Children�s Hospital Medical Center, New York, NY - 1/13/2018
• Case presentation by Mirella Molenschot with panel discussion� with Felix Haas 
  Wilhelmina Children's Hospital, Amsterdam, Netherlands - 1/11/2018
• Double switch operation: always the right choice 
  Wilhelmina Children's Hospital, Amsterdam, Netherlands - 1/10/2018
• PA-branch stenosis after switch: accept or attack? PRO-CON debate with Shakeel Qureshi 
  Wilhelmina Children's Hospital, Amsterdam, Netherlands - 1/9/2018
• An Inconvenient Truth 
  Rochester, MN - 1/7/2018
• The Impact of Public Reporting: The Hype and the Reality 
  Washington, DC - 1/31/2017
• Senning Operation in Anatomical Repair 
  Hamamatsu, Japan - 1/8/2017
• Treatment Strategy for Failed Fontan 
  Hamamatsu, Japan - 1/8/2017
• Surgical Preparation for Fontan 1 Atrioventricular Valve Repair 
  Hamamatsu, Japan - 1/8/2017
• Porcine Small Intestinal Submucosa May Be a Suitable Material for Norwood Arch Reconstruction 
  San Antonio, TX - 1/8/2017
• The Impact of Transparence and Public Reporting on the Congenital Heart Surgery - The Good, The Bad and The Ugly 
  Salt Lake City, UT - 1/6/2017
• Negative Consequences of Public Reporting? The Hype and the Reality 
  Portland, OR - 1/2/2017
• Valvuloplasty for Atrioventricular Valve Regurgitation among Patients with Single Ventricle Anatomy 
  Okayama, Tokyo - 1/30/2016
• The Nikaidoh Procedure for Double Outlet Right Ventricle with an Inlet to Perimembraneous Ventricular Septal Defect and Tricuspid Valve Attachment to the Outlet Septum 
  Okayama, Tokyo - 1/30/2016
• The Two Patch Technique for Repair of Atrioventricular Septal Defects 
  Okayama, Tokyo - 1/30/2016
• Competence and Certification for Congenital Heart Surgery 
  Abu Dhabi, United Arab Emirates - 1/30/2016
• Survival after the Norwood Procedure for Hypoplastic Left Heart Syndrome � How to Improve Early and Late Outcome 
  Okayama, Tokyo - 1/29/2016
• Aortic Valve Repair: I Debated Myself and I Decided Part 2 
  Phoenix, AZ - 1/24/2016
• Are There Negative Consequences to Public Reporting? 
  Atlanta, GA - 1/24/2016
• Surgical Therapy & Outcomes in Postnatal Life 
  Chicago, IL - 1/22/2016
• Surgical Track Phase II QI Focus: Communication with Team and Family Intraoperatively, Surgical Track Special Topic Area: Finer Points of Establishing Pulmonary Flow a... 
  Chicago, IL - 1/22/2016
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Other

• Early Cavopulmonary anastomosis after the Norwood procedure results in excellent Fontan outcome 
  Jaquiss RDB, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS
  1/1/2006
• Limited number of time points weakens this study 
  Tweddell JS, CTSNet Discussion Forums: Oxygen transport in critically ill infants after congenital heart operatio
  1/1/1999
• Advances in the Care of Children with Heart Disease 
  Fedderly RT, Berger S, Frommelt PC, Lewis DA, Dhala A, Pelech AN, Frommelt MA, Friedberg DZ, Thomas JP Jr, Tweddell JS, Litwin SB