
James Frederick Meschia MD (He/Him)
Vascular Neurology
Frances Bartlett Kinne, Ph.D. Professor at Mayo Clinic in Florida; Chair Emeritus, Department of Neurology, Mayo Clinic in Florida Chair, Personnel Committee, Mayo Clinic in Florida
Join to View Full Profile
4500 San Pablo Rd SJacksonville, FL 32224
Phone+1 904-953-2000
Dr. Meschia is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Summary
- James Meschia, MD, FAAN, FAHA, FANA is a Vascular Neurologist in the Cerebrovascular Division of the Department of Neurology in Mayo Clinic in Florida. He is board certified n Neurology and Vascular Neurology by the American Board of Psychiatry and Neurology.
Dr. Meschia's clinical expertise includes management of symptomatic and asymptomatic carotid disease, cerebral small vessel disease, and inherited stroke disorders, including CADASIL, CARASIL, and Fabry disease.
Dr. Meschia earned his bachelor's degree in chemistry from Columbia University in New York and his medical degree from the Johns Hopkins University School of Medicine. He completed his neurology residency at Washington University School of Medicine in St. Louis and his Vascular Neurology fellowship at Indiana University in Indianapolis. He then joined the faculty at Mayo Clinic in Florida where he founded the first accredited stroke center in the Mayo Clinic system and served as Chair for 9 years.
Dr. Meschia's research focuses on management of atherosclerotic carotid stenosis, primary prevention of stroke, and inherited stroke syndromes. He was a member of the Executive Committee of the CREST trial and is co-Principal Investigator of the CREST-2 trial of intensive medical therapy with or without carotid revascularization. He has served as chair of the Writing Group for the American Heart Association's Primary Prevention of Stroke Guidelines and Chair of the AHA Scientific Statement on inherited small vessel diseases. He currently serves as Chair of the Personnel Committee for the Mayo Clinic in Florida.
Education & Training
- Indiana University School of MedicineFellowship, Vascular Neurology, 1996 - 1997
- Washington University/B-JH/SLCH ConsortiumResidency, Neurology, 1993 - 1996
- University of ColoradoInternship, Internal Medicine, 1992 - 1993
- Johns Hopkins University School of MedicineClass of 1992
Certifications & Licensure
- FL State Medical License 1997 - 2027
- AZ State Medical License 2015 - 2025
- IA State Medical License 2018 - 2025
- MN State Medical License 2018 - 2025
- WI State Medical License 2018 - 2025
- MO State Medical License 2018 - 2020
- GA State Medical License 2010 - 2019
- American Board of Psychiatry and Neurology Neurology
- American Board of Psychiatry and Neurology Vascular Neurology
Clinical Trials
- Siblings With Ischemic Stroke Study Start of enrollment: 2000 Dec 01
- Mayo Acute Stroke Trial for Enhancing Recovery Start of enrollment: 2008 Nov 01
- Early Mobilization of Ischemic Stroke Patients Within 24-hours After Intravenous-Tissue Plasminogen Activator (IV-tPA) Start of enrollment: 2011 Jan 01
- Join now to see all
Publications & Presentations
PubMed
- Seizures in Cerebral Amyloid Angiopathy: A Systematic Review and Meta-Analysis.Brin E Freund, Md Manjurul Islam Shourav, Anteneh M Feyissa, James F Meschia, Amen Yonas
Neurology. Clinical Practice. 2025-06-01 - Lipidomic Expression Analysis in Carotid Atherosclerotic Disease: A Systematic Review.Camilo Polania-Sandoval, Seul Kee Byeon, Janelle Hartwell, Mercedes Prudencio, Leonard Petrucelli
Annals of Vascular Surgery. 2025-04-01 - Higher Rate of Reinterventions after Transfemoral Carotid Artery Stenting in Symptomatic Patients: A Retrospective Stroke Center's Cohort Study Between 2015-2024.Camila Esquetini-Vernon, James F Meschia, Josephine Huang, Camilo Polania Sandoval, Mohamed Rajab
Annals of Vascular Surgery. 2025-04-01
Journal Articles
- Ischaemic StrokeJ F Meschia, T Brott, European Journal of Neurology
Press Mentions
- ISC 2021 Session: Prognostication and Early Withdrawal of Care in Ischemic Stroke and ICHMarch 17th, 2021
- Looking Back on 2020: A Successful Year of Research at Mayo Clinic in FloridaJanuary 5th, 2021
- Blood Biomarker Measures Brain Injury in Stroke PatientsNovember 12th, 2020
- Join now to see all
Grant Support
- Carotid Revascularization and Medical Management for Asymptomatic CarotidStenosis Trial - Hemodynamics (CREST-H)COLUMBIA UNIVERSITY HEALTH SCIENCES2017–2027
- Long-Term Observational Extension of Participants in the CREST-2 Randomized Clinical TrialMAYO CLINIC JACKSONVILLE2021–2026
- Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)MAYO CLINIC JACKSONVILLE2014–2026
- The Ninds International Stroke Genetics Consortium StudyNational Institute Of Neurological Disorders And Stroke2010–2011
- Siblings With Ischemic Stroke Study (SWISS)National Institute Of Neurological Disorders And Stroke2005–2009
- Isgs: The Ischemic Stroke Genetics StudyNational Institute Of Neurological Disorders And Stroke2004–2006
- Multicentered Study Of Stroke GeneticsNational Institute Of Neurological Disorders And Stroke2004
- Isgs: The Ischemic Stroke Genetics StudyNational Institute Of Neurological Disorders And Stroke2002–2003
- Multicentered Study Of Stroke GeneticsNational Institute Of Neurological Disorders And Stroke2000–2003
External Links
- Refer a patienthttp://www.mayoclinic.org/medical-professionals/provider-relations/refer-a-patient
- Biohttps://www.mayoclinic.org/biographies/meschia-james-f-m-d/bio-20053766
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence: