JamesGordonHeckerMDPhD

PubMed

• 109 citations
  Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells.
  Shaomin Zou, Keith Scarfo, Michael H. Nantz, James G. Hecker
  International Journal of Pharmaceutics. 2010-04-15
• 6 citations
  Non-Viral Delivery of RNA Gene Therapy to the Central Nervous System.
  Ellen S Hauck, James G Hecker
  Pharmaceutics. 2022-01-11
• 38 citations
  Guideline Adherence and Outcomes in Severe Adult Traumatic Brain Injury for the CHIRAG (Collaborative Head Injury and Guidelines) Study
  Deepak Gupta, Deepak Sharma, Nithya Kannan, Suchada Prapruettham, Charles Mock
  World Neurosurgery. 2016-05-01

Journal Articles

• Anesthesiology in 2037: A Look Back  
  Hecker, JG, Anesthesiology News, 5/5/2017
• Use of a mass spectrometer in the measurement of gas solubilities in blood.  
  Hecker JG and TA Massaro, Biomedical Engineering Vol. 21:157-158
• Characterization of gene expression during stress: implications for anesthesiology and critical care.  
  Hecker JG, Seminars in Anesthesia, Perioperative Medicine and Pain 17:3:187-194
• Awake fiberoptic intubation and intravenous anesthesia in patients with a history suggestive of malignant hyperthermia.  
  Hecker JG and JL Helkowski, The American Journal of Anesthesiology 3:129-131
• Unsymmetrical hydrophobic domains improve in vivo transfection efficiency.  
  Nantz MH, Dicus CW, Hilliard B, Yellayi S, Scarfo KA, Zou S, Hecker JG, Molecular Pharmaceutics 7(3):786-94
• Heat shock proteins as biomarkers for the rapid detection of brain and spinal cord ischemia: A review and comparison to other methods.  
  Hecker JG, McGarvey M, Cell Stress & Chaperones 16(2):119-31
• Clinical Experience with Intraoperative Jugular Venous Oximetry during Pediatric Intracranial Neurosurgery.  
  Sharma D, Siriussawakul A, Dooney N, Hecker JG, Vavilala MS, Pediatric Anesthesia
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Books/Book Chapters

• Microprobe Analysis of Biological Systems. 
  Chapter: Measurement of mass loss during microanalysis: methods and preliminary results 
  Hecker JG and TE HutchinsonEditors: Hutchinson TE and AP Somylo.Academic Press, San Francisco
• Anesthesia and Uncommon Diseases. 
  Chapter: Neurologic Diseases 
  Hecker JG, Baranov D, McClung, H, Kelton, T, Scarfo, KWB Saunders
• Essence of Anesthesia. 
  Chapter: Neuroprotection 
  LA Fleisher and M RoizenElsevierEdition 3rd,
• Fundamentals of Neuroanesthesia: A Physiologic Approach to Clinical Practice. 
  Chapter: Cerebral Ischemia and Neuroprotection 
  Hecker JGEditors: KJ Ruskin, SH Rosenbaum and IJ Rampil.Oxford University Press
• Methods in Molecular Biology, Volume dedicated to synthetic RNA as a tool for cell metabolism modulation. 
  Chapter: Lipid-mediated mRNA delivery 
  Hecker JGEditors: P Rabinovich.Humana Press
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Abstracts/Posters

• Distribution, time course, in-vivo imaging, expression and inflammatory response after non-viral gene delivery to rat and primate CNS.
  Hecker JG, Hauck ES, Nantz MH, Tarantal AF, 8th Annual Meeting of the American Society of Gene Therapy, St. Louis
• In vivo imaging after non-viral RNA delivery to brain.
  Hecker JG, Integrating Molecular Imaging in Drug Discovery and Development conference, Philadelphia
• HSP70 and HSP27 in the CSF of patients undergoing TAAA procedures predict post-operative paralysis.
  Hecker JG, McGarvey M, Association of University Anesthesiologists 57th Annual Meeting, Denver
• Non Viral Gene Delivery to the Primate CNS: Biodistribution and immune response. Oral Presentation, and Chair of Session, American Society for Gene Therapy.
  Hecker JG, 11th Annual Meeting, Boston
• Elevated Heat Shock Proteins 70 and 27 are Correlated with CNS Injury in Surgical Patients Undergoing Deep Hypothermic Circulatory Arrest and Descending Thoracic Aorti...
  Hecker JG, Augostides J, Zou S, Ramachadron S, Bavaria, J, McGarvey M, World Stress Conference, Budapest, Hungary
• Non Viral Gene Delivery to the Primate CNS: A Model for Pre-Operative Neuroprotection.
  Hecker JG, Nantz MH, Tarantal AF, American Society for Gene Therapy, 10th Annual Meeting, Seattle
• Overcoming the hurdle of nonviral gene delivery to non-proliferating cells by RNA based gene transfer.
  Zou, S, Hecker JG, American Society for Gene Therapy 10th Annual Meeting, Seattle
• Non Viral Gene Delivery to the Primate CNS: A Model for Operative Neuroprotection.
  Hecker JG, Association of University Anesthesiologists 54th Annual Meeting, Chicago
• Elevated Heat Shock Proteins 70 and 27 are Correlated with CNS Injury in Surgical Patients Undergoing Deep Hypothermia Circulatory Arrest and Descending Thoracic Aorti...
  Hecker JG, Zou S, Augostides J, Ramachadron S, Thurber A, Bavaria JE, McGarvey M, Biomarkers Conference, Booth Bay, ME
• Non-Viral DNA and mRNA Gene Delivery to the CNS for Neuroprotection.
  Hecker JG, Tarantal AF, Nantz MH, European Society for Gene Therapy, Prague, Czech Republic
• Non-Viral DNA and mRNA Gene Delivery to the CNS for Neuroprotection and Following Neurotrauma.
  Hecker JG, Tarantal AF, Nantz MH, Society for Neuroscience 35th Annual Meeting, Washington, DC
• Applications: When is Short Term Expression Better?
  Hecker JG, 5th Annual National Meeting of the American Society of Gene Therapy, Boston, MA
• In-vivo time course of reporter gene expression after nucleic acid delivery to the lateral ventricle in rat brain.
  Hauck ES, Zou S, Nantz MH, Hecker JG, 8th Annual Meeting of the American Society of Gene Therapy, St. Louis
• Gene delivery to primary neuronal cells.
  Zou S, Hauck ES, Nantz MH, Hecker JG, 8th Annual Meeting of the American Society of Gene Therapy, St. Louis
• Distribution, Expression, and Inflammatory Response after Non-viral Gene Delivery to the Primate CNS: A Model for Operative Neuroprotection.
  Hecker JG, Association of University Anesthesiologists 52nd Annual Meeting, Baltimore, MD
• Non-Viral DNA and mRNA Gene Delivery to the CNS for Neuroprotection and Following Neurotrauma.
  Hecker JG, Tarantal AF, Nantz MH, Society for Neuroscience 34th Annual Meeting, San Diego, CA
• Non-Viral DNA and mRNA Gene Delivery to the CNS for Neuroprotection and Following Neurotrauma.
  Hecker JG, Tarantal AF, Nantz MH, 7th Annual Meeting of the American Society of Gene Therapy, Minneapolis, MN
• Non-viral DNA and mRNA gene delivery to the CNS pre-operatively for neuroprotection and following neurotrauma.
  Hecker JG, Association of University Anesthesiologists 51st Annual Meeting, Sacramento, CA
• Non-viral DNA and mRNA gene delivery to the CNS pre-operatively for neuroprotection and following neurotrauma.
  Hecker JG, American Society of Anesthesiologists National Meeting, San Francisco, CA
• Optimization of non-viral DNA and mRNA gene delivery to the CNS following neurotrauma and pre-operatively for neuroprotection.
  Hall LL, Massey-Anderson D, Nantz MH, Hecker JG, Society for Neuroscience 32nd Annual Meeting, Orlando, FL
• Comparative analysis of cationic lipid-mediated RNA and DNA gene delivery in non-proliferating cells.
  Hall LL, Massey D, Hecker JG, 5th Annual National Meeting of the American Society of Gene Therapy, Boston, MA
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