James W Freston MD PhD, FAGA

PubMed

• 18 citations
  Clinical Pattern of Tolvaptan-Associated Liver Injury in Trial Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD): An Analysis of Pivotal Clinical ...
  David H Alpers, James H Lewis, Christine M Hunt, James W Freston, Vicente E Torres
  American Journal of Kidney Diseases. 2023-03-01
• 21 citations
  Consensus Guidelines: Best Practices for Detection, Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chroni...
  William R. Treem, Melissa Palmer, I. Lonjon-Domanec, Daniel Seekins, Lara Dimick-Santos
  Drug Safety. 2021-02-01
• 19 citations
  Real-world safety of palbociclib in breast cancer patients in the United States: a new user cohort study.
  Daniel C. Beachler, Cynthia de Luise, Aziza Jamal-Allial, Ruihua Yin, Devon H. Taylor
  BMC Cancer. 2021-01-25

Journal Articles

• Liver Complications Following Treatment of Hematologic Malignancy with Anti‐cd22‐Calicheamicin (Inotuzumab Ozogamicin)  
  James W Freston, Laurie D DeLeve, George B McDonald, Hepatology
• Clinical and histological features of fluoroquinolone-induced liver injury  
  Eric S. Orman ES, Conjeevaram HS, Vuppalanchi R, Freston JW, Rachon J, Kleiner DE, Hayashi PH, Clinical Gastroenterology and Hepatology, 1/1/2011
• A Causality assessment in drug-induced liver disease using a structured expert opinion process: Comparison to the Roussel Unclaf causality assessment method  
  Rockey DC, Seeff, LB, Rochon J, Freston J. Chalasani N, Bonacine M, Fontana RR, Hayashi P, Hepatology, 1/1/2010
• Drugs associated with hepatotoxicity and their reporting frequency of liver adverse events in VigiBaseTM: Unified list based on International collaborative work  
  Suzuki A, Andrade RJ , Bjornsson E, Lucena IM, Lee W, Yuen N, Hunt CN, Watkins P, Freston JW, Drug Safety, 1/1/2010
• Changes of gastric histology in patients with erosive oesophagitis receiving long-term lansoprazole maintenance therapy  
  Haber M, Hunt B, Freston JW, Peura DA, Kovacs TO, Atkinson S, Hisada M, Alimentary Pharmacology & Therapeutics, 1/1/2010
• The clinical safety of long-term lansoprazole for the maintenance of healed erosive oesophagitis  
  Freston JW, Hisada M, Peura DA, Haber MM, Kovacs TO, Atkinson S, Hunt B, Aliment Pharmacol Therap, 1/1/2009
• Liver safety in patients with type 2 diabetes treated with pioglitazone: Results from a 3-year, randomized, comparator-controlled study  
  Tolman K, Freston JW, Kupfer S, Perez A, Drug Safety, 1/1/2009
• Use of pH-Impedance Testing to Evaluate Patients With Suspected Extraesophageal Manifestations of Gastroesophageal Reflux Disease  
  Malhotra A, Freston JW, Aziz K, J.Clin.Gastroenter., 1/1/2008
• Vector analysis to detect hepatotoxicity signals in drug development  
  Trost CD, Freston JW, Drug Information Journal, 1/1/2008
• Colorectal cancer screening: a retrospective study of compliance with guidelines in a university-based primary care practice  
  Mulhotra A, Freston JW, Soriano M, Aziz K, Quality in Primary Care, 1/1/2007
• Recurrent Pneumonia from severe nonacid reflux: a case report and discussion  
  Mulhotra A, Freston JW, Soriano M, Aziz K, Connecticut Medicine, 1/1/2007
• Advancing Patient Care for Chronic Hepatitis B  
  Wright TL, Avunduk C, Dienstag JL, Freston JW, Jacobson IM, Nord HJ, Sherman M, Am J Gastroenterol, 1/1/2006
• Our new president – David A Peura, MD  
  Freston JW, Yoshida CM, Gastroenterol, 1/1/2005
• Rating the severity of the medical consequences of drug-induced liver injury  
  Slavin DE, Schlichtine CL, Freston JW, Regulatory Toxicology and Pharmacology, 1/1/2005
• Approaches to the long-term management of adults with GERD: proton pump inhibitor therapy, laparascopic fundoplication or endoscopic therapy?  
  Freston JW, Triadofilopoulas G, Aliment Pharmacol Ther, 1/1/2004
• Management of GERD in children and Adults  
  Gold B, Freston JW, Pediatric Gastroenterology, 1/1/2003
• Comparative pharmacokinetics and safety of lansoprazole oral capsules and fast-disintegrating tablets in healthy subjects  
  Freston JW, Chiu YL, Mulford DJ, Ballard II ED, Aliment Pharmacol Ther, 1/1/2003
• Gastroesophageal reflux in children: pathogenesis, prevalence, diagnosis and role of proton pump inhibitors in treatment  
  Gold BD, Freston JW, Pediatr Drug, 1/1/2002
• Differences among the PPIs  
  Howden CW (editor), Freston JW, SCOPE, 1/1/2002
• Motion – All patients with GERD should be offered once-in-a-lifetime endoscopy: Arguments against the motion  
  Freston JW, Can J Gastroenterol, 1/1/2002
• Looking for Hepatotoxicity, Working up Patients, and Assessing Causality  
  Freston JW, 2/12/2001
• Attributable risk of H, pylori in peptic ulcer disease Does declining prevalence of infection in general population explain increasing frequency of non-H pylori ulcers?  
  Sugiyama T, Nishikawa K, Komatsu Y, Ishizuka J, Mizushima T, Kumagai A, Kato M, Saito N, Takeda H, Asaka M, Freston JW, Dig Dis Sci, 1/1/2001
• Should we eradicate H pylori before long-term anti-reflux therapy?  
  Freston JW, Gut, 1/1/2001
• Review article: Role of proton pump inhibitors in non-H pylori-related ulcers  
  Freston JW, Aliment Pharmacol Therap, 1/1/2001
• The evolving roles of proton pump inhibitors in long-term care of acid related disorders  
  Freston JW, Garnett W, Annals of Long-Term Care, 1/1/2001
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Books/Book Chapters

• UpToDate, Revised 
  Chapter: H. pylori-negative ulcer disease. 
  Varadarajulu S, Freston JWEditors: Rose BD.UpToDate, Wellesley, MA2005
• Focus on GERD and NSAID-related ulcers. 
  Chapter: Patient with recurrent nocturnal heartburn. 
  Page 19 - 25Freston JWEditors: Howden CW, and Peura DA.McMahon Publishing Group, New York2004
• UpToDate 
  Chapter: H. pylori-negative ulcer disease. 
  Varadarajulu S, Freston JWEditors: Rose BD.UpToDate, Wellesley, MA2002
• Helicobacter pylori and gastritis – Basic mechanisms to clinical cure 2002. 
  Chapter: Helicobacter pylori eradication is not necessary before long-term proton pump inhibitor treatment. Helicobacter pylori 
  Page 311 - 317Freston JWEditors: Hunt RH, Tytgat GNJ.Kluwer Academic Publishers, Norwell, MA2002
• Diseases of the gastroesophageal mucosa: The acid related disorders. 
  Chapter: Gastroesophageal reflux disease: Diagnosis and treatment. 
  Page 137 - 166Cymorek, JH, Freston, JWEditors: Freston JW.Humana Press Inc., Totowa, NJ2001
• Diseases of the gastroesophageal mucosa: The acid related disorders. 
  Chapter: Peptic ulcer disease: Overview and management. 
  Page 3 - 27Varadarajulu S, Freston JWEditors: Freston JW.Humana Press Inc., Totowa, NJ2001
• Diseases of the gastroesophageal mucosa: The acid-related disorders. 
  Page 1 - 199Editors: Freston JW.Humana Press Inc., Totowa, NJ2001
• CME series for primary care physicians. Part 1 
  Chapter: Medical Simulations. Management of Acid-Related Disorders. 
  Varadarajulu SS, Freston JWAlbert Einstein College of Medicine2000
• Helicobacter pylori: In: Helicobacter pylori and gastritis – Basic mechanisms to clinical cure 2000. 
  Chapter: Proton pump inhibitors do not accelerate the development of gastric atrophy in Helicobacter pylori gastritis. 
  Page 269 - 280Freston JWEditors: Hunt RH, Tytgat GNJ.Kluwer Academic Publishers, Norwell, MA2000
• The 83rd General Meeting of Japanese Society of Gastroenterology - Future Trends in Gastroenterology. 
  Chapter: Overviews of controversies in acid-related diseases: Implication for the future. 
  Page 5 - 16Freston JWEditors: Nakazawa S.Life Science Publishing, Tokyo1998
• Digestive Diseases Self-Education Program (DDSEP) A core curriculum and self-assessment in gastroenterology and hepatology. 
  Editors: Freston JW.Kendall/Hunt Publishing Co., Dubuque, IA1998
• The Toxicology Forum - Given Institute, Aspen, CO 
  Chapter: Mechanisms of induction and toxicological significance of gastric carcinoids: Relevance of rodent tumors to humans. 
  Page 729 - 736Freston JWThe Toxicology Forum, Inc., Washington, DC1998
• Helicobacter pylori - Basic mechanisms to clinical cure 1998. 
  Chapter: Helicobacter pylori: The clinical agenda. 
  Page 490 - 498Freston JWEditors: Hunt RH, Tytgat GNJ.Kluwer Academic Publishers, Norwell, MA1998
• Gastrointestinal pharmacology and therapeutics. 
  Chapter: Acid-related disease. 
  Page 21 - 78Freston JWEditors: Jacobson ED, Friedman G, McCallum RW.Lippincott Raven Publishers1997
• Gastrointestinal pharmacology and therapeutics. 
  Chapter: Helicobacter pylori induced gastric and ulceration: Epidemiology, pathophysiology and therapeutics. 
  Page 21 - 29Malfertheiner P, Freston JWEditors: Jacobson ED.Lippincott Raven Publishers1997
• Helicobacter pylori: Basic mechanisms to clinical cure 1996. 
  Chapter: Helicobacter pylori, acid, gastritis, atrophy and progression to cancer: A critical view. 
  Page 245 - 254Freston JWEditors: Hunt R, Tytgat GNJ.Kluwer Academic Publishers1996
• Critical issues in the era of proton pump inhibitors: Point and counterpoint. 
  Freston JW1995
• Proton pump inhibitors and acid-related disorders. 
  Chapter: The long-term management of peptic ulcer disease: Analysis of approaches and recommendations. 
  Page 121 - 136Porro GB, Freston JW, Lazzaroni MEditors: Hunt R.Adis International Limited, Osaka1994
• Proton pump inhibitors and acid-related disorders. 
  Chapter: The medical treatment of acute peptic ulcer disease. 
  Page 101 - 117Freston JW, Porro GBEditors: Hunt R.Adis International Limited, Osaka1994
• Do PPI effects on the cytochrome P450 system have implications to significant drug interactions? The Esophageal Mucosa. 
  Chapter: PPI effects on the cytochrome P450 system. 
  Page 460 - 464Rodrigues AD, Freston JWEditors: Giuli R, Tytgat G, Dameester T, Galmisch JP.Elsevier, Amsterdam1994
• Atlas of gastroenterology. 
  Chapter: Chapter 47: Approach to gastrointestinal problems associated with common clinical conditions. 
  Page 92 - 97Freston JW, Moore JREditors: Yamada T.JB Lippincott, Philadelphia1992
• Textbook of gastroenterology. 
  Chapter: Chapter 47: Approach to gastrointestinal problems associated with common clinical conditions. 
  Page 928 - 942Freston JW, Moore JREditors: Yamada T.JB Lippincott, Philadelphia1991
• Practical approaches to the management of dyspepsia. 
  Chapter: The patient's perspective of dyspepsia. 
  Page 7 - 10Freston JWEditors: Colin-Jones DG.The Medicine Group, Langhorne1989
• Concepts and controversies in gastroenterology. 
  Page 1 - 48Editors: Freston JW, Pounder R.Norwegian University Press, Norway1987
• Postgraduate medicine: Custom communications, Cimetidine '85 new insights from a decade of continuing research. 
  Editors: Freston JW, Isenberg JI.McGraw-Hill, New York1985
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Other

• Use and limitations of the RUCAM in hepatotoxicity adjudication. 
  Freston JW
  1/1/2006
• Method for predicting the onset or change of a medical condition. 
  DC Trost, JW Freston, J Ostroff, US Patent App. 10/968,675, 2004 - Google Patents US 20050119534A1 (19) United States (12) Patent Ap
  6/2/2005
• Digestive Diseases Self-Education Program. A core curriculum and self assessment in gastroenterology and hepatology. CD-ROM, syllabus, atlas, and exam. 
  Freston JW, A CME Program, American Gastroenterological Association
  1/1/1998
• Point and Counterpoint: Issues and Answers in Digestive Disease 
  Freston JW, CD-ROM CME Accredited Program
  1/1/1997
• Peptic Ulcer Disease (Video) 
  Freston JW, Time-Life Books
  1/1/1996
• The AGA: Second Century of Excellence (Video) 
  Freston JW
  1/1/1996
• Highlights of The World Congress of Gastroenterology -Australia, Audiotape for General Physician 
  Freston JW
  1/1/1990
• Highlights of The World Congress of Gastroenterology - Brazil, i. Audiotape for General Physician 
  Freston JW
  1/1/1986
• Management of Acute Abdominal Pain - Computerized Interactive Laser Disc 
  Freston JW, i. WICAT, New York
  1/1/1985
• Approach to Peptic Ulcers - Computerized Interactive Laser Disc 
  Freston JW, i. WICAT, New York
  1/1/1984
• Management of Upper Gastrointestinal Bleeding - Computerized Interactive Laser Disc 
  Freston JW, i. WICAT, New York
  1/1/1983
• Highlights of The World Congress of Gastroenterology - Sweden, Audiotape for General Physician 
  Freston JW
  1/1/1982
• Experimental cholelithiasis. Ph.D. Thesis 
  Freston JW, (Medicine) University of London
  1/1/1967
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