JamesAlexanderFaginMD

Endocrinology • New York, NY

Diabetes, Lipid Metabolism, Thyroid

Head, Division of Subspecialty Medicine Memorial Sloan Kettering Cancer Center

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Office
530 East 74th Street
New York, NY 10021

Education & Training

Cedars-Sinai Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1983 - 1985
University of Buenos AiresClass of 1973

Certifications & Licensure

CA State Medical License 1986 - Present
FL State Medical License 2021 - Present
NY State Medical License 2006 - 2026
NJ State Medical License 2021 - 2025
OH State Medical License 1995 - 2007
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Elected Member Association of American Physicians, 2001
Top Doctors: New York Metro Area Castle Connolly, 2014
Elected Member The American Society for Clinical Investigation, 1995

Clinical Trials

Reacquisition of Radioactive Iodine (RAI) Uptake of RAI-Refractory Metastatic Thyroid Cancers by Pretreatment With the Selective MEK Inhibitor AZD6244 Start of enrollment: 2009 Sep 01
Completed
Not Applicable
Vemurafenib Plus Copanlisib in Radioiodine-Refractory (RAIR) Thyroid Cancers Start of enrollment: 2020 Jun 26
Completed
Phase 1
Roles: Contact

Publications & Presentations

PubMed

26 citations
Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.
Eric Wang, Jose Mario Bello Pineda, Won Jun Kim, Sisi Chen, Jessie Bourcier
Cancer Cell. 2023-01-09
171 citations
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer
Thomas Wiesner, William Lee, Anna C. Obenauf, Leili Ran, Rajmohan Murali
Nature. 2015-10-15
129 citations
Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy.
Ian Ganly, Julio Cezar Ricarte Filho, Stephanie Eng, Ronald Ghossein, Luc G. T. Morris
The Journal of Clinical Endocrinology and Metabolism. 2013-03-29

Journal Articles

Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid Cancers
Steven M Larson, Sofia Haque, Duan Li, R Michael Tuttle, Mona M Sabra, Alan L Ho, Eric J Sherman, Ravinder K Grewal, James A Fagin, David G Pfister, Ronald A Ghossein, The Journal of Clinical Endocrinology and Metabolism
Radioactive Iodine-Related Clonal Hematopoiesis in Thyroid Cancer Is Common and Associated with Decreased Survival
James Fagin, MD, The Journal of Clinical Endocrinology and Metabolism
Methodology, Criteria and Characterization of Patient-Matched Thyroid Cell Lines and Patient-Derived Tumor Xenografts
James A Fagin, Stephen D Rohl, Robert C Smallridge, Stefan K Grebe, The Journal of Clinical Endocrinology and Metabolism

Lectures

Targeting Deregulated Signaling in Thyroid Cancer
ENDO 2019 - New Orleans, LA - 3/25/2019

Press Mentions

Novel Agent Nixes Radioiodine Resistance in Thyroid CancerOctober 7th, 2020
Bench to Bedside: Translating Science from the Lab to the ClinicMay 2nd, 2019
87th Annual Meeting NewsOctober 20th, 2017
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Grant Support

Oncogenic Events In Thyroid NeoplasiaNational Cancer Institute2006–2012
Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute2006–2012
A Validated Resource Of Thyroid Cancer Cell Lines For Pathway DiscoveryNational Cancer Institute2009–2010
Paracrine Igf/Gfbp Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
Paracrine Igf/Gfbp Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2006
Oncogenic Events In Thyroid NeoplasiaNational Cancer Institute1997–2006
Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute1995–2004
Biological And Physiological Sciences Review SectionCenter For Scientific Review2001–2002
Paracrine IGF/IGFBP Interactions In VivoNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2002
Molecular Pathophysiology Of Thyroid Cell GrowthNational Center For Research Resources2000–2001
N-Acetylcysteine As A Potential Treatment For Methamphetamine DependenceCenter For Scientific Review2000
Insulin LIKE Growth Factor I In Arterial Wall InjuryNational Heart, Lung, And Blood Institute1995–1996
Insulin LIKE Growth Factor I In Arterial Wall InjuryNational Heart, Lung, And Blood Institute1994
Molecular Pathophysiology Of Thyroid Cell GrowthNational Cancer Institute1989–1993
Tumor Suppressor Genes In Human Thyroid NeoplasmsNational Cancer Institute1990
Human Growth Hormone-Secreting Hybrid CellsNational Institute Of Diabetes And Digestive And Kidney Diseases1985–1986